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The Effect of Glycopyrrolate and Neostigmine Mixture on the Heart Rates

Chung SS, Jeong CY, Im WM

  • KMID: 1932802
  • Korean J Anesthesiol.
  • 1983 Dec;16(4):301-305.
When antagonism to neuromuscular block is needed, glycopyrrolate is the new anticholinergic drug emplyed to counteract the muscarinic action of neostigmine. To know the effect on heart rate after an...
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Effects of Neostigmine on Tracheal Smooth Muscle Contraction in Rabbits

Kim TH, Shim JY, Park HJ, Kwon OK

BACKGROUND: Neostigmine, a cholinesterase inhibitor, is known to reverse the neuromuscular blocking action induced by nondepolarizing muscle relaxants at the end of general anesthesia. Some authors, however, reported that neostigmine...
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Peripheral Effect of Neostigmine and L-NAME on Acute Arthritis in the Rat

Park SJ, Lym HJ, Jang SH, Yoon SM

BACKGROUND: The spinal administration of neostigmine has been shown to produce analgesia, but this analgesia is limited by adverse effects. This study was designed to determine whether intra-articular neostigmine results...
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The Effects of Atropine and Glycopyrrolate mixed to Neostigmine on Heart Rate in Anesthetized Pediatric Patients

Lee KS, Park DP

Fourty pediatric patients anesthetized with halothane-nitrous oxide-oxygen, who received pancronium for the maintenance of muscular relaxation, were divided into two groups. On anesthesia, in group l, atropine(20ug/kg) and neostigmin(40ug/kg), and...
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The Change of Heart Rate following the mixed injection of Atropine and Neostigmine for Non-Depolarizing Neuromuscular Blocking Agent-Pancuronium

Kim KW, Oh YS, Kim KS, Kim BD, Kim SD, Kwon MI

  • KMID: 2357509
  • Korean J Anesthesiol.
  • 1979 Dec;12(4):348-354.
Around the time of recovery from general anesthesia we usually use atropine and neostigmine to counteract the effect of muscle relaxant that is remaining in the body. We used...
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The Effects of Atropine and Neostigmine on Heart Rate

Jin HY, Choi BK

  • KMID: 2349621
  • Korean J Anesthesiol.
  • 1984 Jun;17(2):96-101.
To confirm the effects of atropine and neostigmine on heart rate in balanced anesthesia with tramadol (Tridol) two groups of patients who were included in class I by A.S.A. classification...
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The Effect of Recovery from Vecuronium following Neostigmine Administration in Children and Adult during Halothane Anesthesia

Oh BH, Kwak HS

To determine Whether neoatigmine had different effecta in pediatric patients and adults during vecuronium neuromuscalar blockade, the rate of recovery following neostigmine admimistration was compared in children (n=10, group I)...
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The Effects of Intrathecal Neostigmine on Postoperative Analgesia in Patients Undergoing Total Knee Replacement

Cho SY, Kim KS, Oh MK

BACKGROUND: Intrathecal neostigmine causes analgesia in dose-dependent pattern. This study was designed to examine postoperative analgesia with intrathecal neostigmine in a randomized, blinded trial with tetracaine as the active control...
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Action of Atropine and Glycopyrrolate on the Muscarinic Effect of Neostigmine

Koo BH, Yune GJ, Choi SJ

  • KMID: 2349529
  • Korean J Anesthesiol.
  • 1984 Mar;17(1):53-58.
Sixty patients anesthetized with nitrous oxide-oxygen-halothane, who received pancuronium for the maintenance of muscular relaxation were divided into three group of twenty each. Ath the end of anesthesia, the patients...
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The Divided Doses of Neostigmine for the Rapid Recovery at Profound Muscle Relaxation of Pancuronium in Rabbits

Kim KS, Na DJ, Jun JH, Shin WJ

BACKGROUND: The reversal of neuromuscular blocker might be accelerated if the anticholinesterase was administered in divided doses. This study has been conducted to evaluate the correct ratio of divided doses...
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Intravenous Neostigmine Test for Diagnosis of Ocular Myasthenia Gravis

Kim DI, Lee BJ, Kim SJ

PURPOSE: In the present study, we evaluated the validity of intravenous neostigmine administration combined with alternate prism cover test (APCT) measurement as a confirmatory diagnostic method for confusing cases of...
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The Effects of Atropine and Neostigmine on Heart Rate and Electrocardiogram in Anesthetized Patients

Hwang YH, Ahn KY, Kim IK, Kim YS, Park DH, Kim WS

  • KMID: 2357568
  • Korean J Anesthesiol.
  • 1979 Jun;12(2):140-144.
Four modes of administrating atropine and neostigmine to reverse pancuronium block were studied in thirty-eight anesthetized patients, with special reference to their effects on heart rate and electrocardiogram. At the...
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The Time of Neostigmine Antagonism for the Rapid Recovery of Profound Muscle Relaxation in Rabbits

Kim YK, Hwang SE, Kim KS, Chon SU

BACKGROUND: A question was whether it was preferable to give the reversal agent when profound block was present or wait for some spontaneous recovery before antagonizing the block. This study...
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A Case of Prolonged Paresis following GaIIamine on Reoperation Patient

Lee SJ, Choi YS, Kim YH, Shin JS

  • KMID: 2357951
  • Korean J Anesthesiol.
  • 1975 Jun;8(1):97-99.
The authors have experience of a case of prolonged paresis following administration of galamine triethiodide to a patient undergoing reoperation. The muscular weakness continued for 20 hours, necessitating artificial ventilation...
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Reversal of Neuromuscular Blockade with Neostigmine Does not Increase the Incidence of Postoperative Nausea and Vomiting

Lee BH

BACKGROUND: Postoperative nausea and vomiting (PONV) are still very common complications after general anesthesia. Some studies have reported that reversal of neuromuscular block by neostigmine is an important factor contributing...
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The Effects of Temperature Changes on the Acetylcholine and Neostigmine Induced Contraction of Rabbit Trcheal Smooth Muscle

Kwon OK, Kim CS, Ryu KH

BACKGROUND: The body temperature of a patient changes changes during general anesthesia and cholinesterase inhibitor is usually administered at the end of general anesthesia to reverse the neuromuscular blocker effect....
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Effect of Doxapram on the Recovery from Vecuronium and Atracurium Neuromuscualr Block

Park MH, Moon KH, Lee MA

The purpose of this study is to investigate the effects of doxapram on the rates of spontaneous and neostigmine-induced recovery from neuromuscular block with vecuronium and atracurium. Following intravenous...
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The antagonistic effect of neostigmine on rocuronium-, clindamycin-, or both-induced neuromuscular blocking in the rat phrenic nerve-hemidiaphragm

Kim SS, Lee SI, Chung CJ, Lee SC

BACKGROUND: Neostigmine augments clindamycin-induced neuromuscular block and antagonizes rocuronium-induced neuromuscular block; however, it remains unclear whether neostigmine enhances the neuromuscular blocking (NMB) that is caused by combinations of rocuronium and...
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Analgesic Effect of Epidural Fentanyl-Neostigmine after Radical Subtotal Gastrectomy

Kim SY, Yoon MH, Kim SJ, Chung ST

BACKGROUND: This study evaluated the efficacy of an epidural single dose of neostigmine combined with fentanyl to provide postoperative analgesia after radical subtotal gastrectomy. METHODS: Fifty two adults patients with...
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Interaction between Neostigmine and Morphine in the Neuropathic Pain Model

Hwang JH, Kim YK, Han SM, Lee DM

BACKGROUND: Spinally administered neostigmine, but not morphine, has been well known to reverse the mechanical allodynia in human and animal studies. The efficacy of morphine in neuropathic pain state is...
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