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The Effect of Adriamycin on Ionic Currents in Single Cardiac Myocytes of the Rabbit

Sohn S

  • KMID: 1662027
  • J Korean Pediatr Soc.
  • 1995 Aug;38(8):1093-1106.
No abstract available.
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Depression of L-type Ca2+ and transient outward K+ currents in endotoxin-treated rat cardiac myocytes

Park KS, Lee BS, Kong ID, Lee JW

  • KMID: 2071566
  • Korean J Physiol Pharmacol.
  • 1999 Dec;3(6):623-630.
Decreased cardiac contractility occurs in endotoxicosis, but little is known about the ionic mechanism responsible for myocardial dysfunction. In this study, we examined the changes in Ca2+ and K+ currents in cardiac myocytes...
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Effect of beta-amyloid Peptide on Fine Structure of Cardiac Myocytes in Culture

Sung EK, Lee YS, Sung HK, Park JH, Kim JY, Song IH, Lee YC

  • KMID: 2224560
  • Korean J Anat.
  • 2000 Aug;33(4):497-510.
Several predetermined concentrations of beta-amyloid peptide, (betaA) were administered to the rat cardiac myocyte cultures for three days to determine the effects of betaA. Stainings with congo red and crystal...
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Identification of a Calcium-activated Potassium Channel Gene Expressed in Rat Cardiac Myocytes

Park IS, Jeon HK, Kim NS, Ahn YM, Park CS, Lee HB

  • KMID: 2335491
  • J Korean Pediatr Soc.
  • 2000 Jul;43(7):905-912.
PURPOSE: Calcium-activated potassium channels(KCa) may be involved in the transient outward current of the first phase of cardiac action potential. But it is still not clear whether cardiac myocytes express any Kca....
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Ultrastructural changes in the cardiac myocyte and the extracellular space in different duration of ischemia

Kim HD, Rah BJ, Chang CH

  • KMID: 1686732
  • Korean J Anat.
  • 1992 Mar;25(1):91-103.
No abstract available.
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The Characteristics of Spontaneous Action Potential of Cardiac Myocytes in Rabbit Pulmonary Veins

Choi KJ, Kim WT, Nam GB, Song JK, Kim JJ, Park SW, Park SJ, Park CH, Kim YH, Choi YS, Leem CH

BACKGROUND AND OBJECTIVES: Atrial fibrillation is one of the most prevalent arrhythmia with clinical significance. Recently, some subset of paroxysmal atrial fibrillation was reported to be originated from a focal,...
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Regulation of Mg2+ release in guinea pig heart and isolated ventricular myocytes by alpha1-adrenergic stimulation

Kang HS, Chang SE, Kim JS

  • KMID: 2285190
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):717-730.
Mg2+ is the fourth most abundant cation in cellular organisms. Although the biological chemistry and the physiological roles of the magnesium ion were well known, the regulation of intracellular Mg2+ in mammalian cells...
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Stretch-activated K+ Channels in Rat Atrial Myocytes

Youm JB

  • KMID: 1607519
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):341-348.
Mechanical stimuli to the cardiac myocytes initiate many biochemical and physiological events. Stretch-activated cation channels have been suggested to mediate these events. In this study, cell-attached and inside-out excised-patch clamp...
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Protective Effect of Probucol against Adriamycin-Induced Apoptosis in Cultured Rat Cardiac Myocytes

Lee SJ, Lee DS, Jung YW

  • KMID: 2207532
  • J Korean Pediatr Soc.
  • 2000 Jun;43(6):746-754.
PURPOSE: In adriamycin(ADR)-induced cardiomyopathy, several different mechanisms are suggested. However, little information is available regarding the role of apoptosis. In the present study, we examined the induction of apoptosis on...
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Effects of bradykinin on intracellular calcium transients in cardiac myocytes

Park CO, Kim YM, Han JH, Allen DG, Hong SG

  • KMID: 2071565
  • Korean J Physiol Pharmacol.
  • 1999 Dec;3(6):615-621.
In spite many evidences has supported the cardioprotective effect of bradykinin, its direct effects at the cell level are still under question. We investigated the both effects of bradykinin (BK) on Ca2+-related ionic...
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Role of Plasmalogen-derived Lysolipids onthe Pathophysiology of Myocardial Ischemia

Pio LH, Kim JH

  • KMID: 1883693
  • Chonnam Med J.
  • 2007 Dec;43(3):168-176.
To clarify the role of plasmalogen-derived lysolipids on pathophysiology of myocardial ischemia, effects of the lysolipids on the regulation of ATP-sensitive K+ channel (K(ATP) channel) activities were examined in enzymatically...
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Expression of Connexin 43 in the Myocardium in Sudden Unexplained Nocturnal Death Syndrome

Huh GY, Ahn JW, Kim EY

Sudden unexplained nocturnal death syndrome (SUNDS) occurs predominantly in Southeast Asian people including Koreans. SUNDS is problematic for forensic pathologists because the diagnosis depends on the "exclusion of diagnosis." Moreover,...
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Effect of prostaglandins D2, E2 and I2 on the regulation of KATP channel activity in rat cardiac myocytes

Ju JM, Nah SY, Kim JH

  • KMID: 2071552
  • Korean J Physiol Pharmacol.
  • 1999 Oct;3(5):507-512.
Contribution of prostaglandins D2, E2 and I2 (PGD2, PGE2 and PGI2) on the regulation of ATP-sensitive K+ channel (KATP channel) was investigated in isolated single rat ventricular cardiac myocytes using the patch clamp...
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Long Noncoding RNA MHRT Protects Cardiomyocytes against H2O2-Induced Apoptosis

Zhang J, Gao C, Meng M, Tang H

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. The exploration of new biomarkers with high sensitivity and specificity for early diagnosis of AMI therefore becomes...
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Death and Survival of Cardiomyocytes in Acute Ischemia

Lee SH, Kim YD

Ischemia is the most common and important cause of injury to cardiomyocytes. Acute ischemia causes profound derangement of the cellular energetics and metabolism, and this ultimately leads to cell death....
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Mitochondrial Dynamics in the Heart as a Novel Therapeutic Target for Cardioprotection

Hwang SJ, Kim W

Traditionally, mitochondria have been regarded solely as energy generators for cells; however, accumulating data have demonstrated that these complex organelles play a variety of roles within the cardiomyocyte that extend...
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Metabolic Crosstalk between the Heart and Fat

Ferrero KM, Koch WJ

It is now recognized that the heart can behave as a true endocrine organ, which can modulate the function of other tissues. Emerging evidence has shown that visceral fat is...
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Influence of Nitric Oxide Donor on the Regulation of ATP-sensitive K+ Channel Activity in Cardiac Myocytes

Ju JM, Shin DH, Lee WS, Park HW, Cho JG, Kim JH

  • KMID: 2116759
  • Chonnam Med J.
  • 2002 Jun;38(2):135-145.
It was investigated that effects of nitric oxide donors on the ATP-sensitive K+ channel (KATP channel) in isolated mouse ventricular cardiac myocytes using patch clamp techniques. In perforated whole-cell patches,...
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Effects of PGI2 on the ATP-sensitive Potassium Channel Activity in the Isolated Rat Cardiac Myocytes

Ju JM, Choi DS, Piao LH, Kim JH

  • KMID: 1613959
  • Chonnam Med J.
  • 2003 Sep;39(3):162-170.
It was examined that the effects of PGI2 on the ATP-sensitive potassium channel (KATP channel) activity in the rat myocardium using patch clamp and action potential measurement techniques. PGI2, doses...
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Ultrastructural Injury and Its Mechanism of Cultured Cardiac Myocytes under Anoxia-Reoxygenation

Park JH, Kim JY, Jeong SR, Lee YC

  • KMID: 1530059
  • Korean J Anat.
  • 1998 Apr;31(2):225-240.
Abrupt reoxygenation (or reperfusion) after anoxia (or ischemia)-induced injury resulted in the loss of contractile property, destruction of cell organelles, and ultimately, cell death in cardiac myocytes. This phenomenon has...
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