- Therapeutic Drug Monitoring of Mycophenolic Acid
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Yun YM, Kim JQ
- KMID: 2040474
- J Lab Med Qual Assur.
- 2008 Dec;30(2):243-247.
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- Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year
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Rhu J, Lee KW, Park JB, Kim SJ
- KMID: 2430587
- J Korean Soc Transplant.
- 2018 Dec;32(4):75-83.
- doi: 10.4285/jkstn.2018.32.4.75
BACKGROUND: This study was designed to analyze the clinical usefulness of mycophenolic acid trough concentration monitoring in kidney transplantation patients who were maintained with cyclosporine. METHODS: The data of patients who... -
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- IgG4-related Disease Controlled by a Low-dose Steroid and Mycophenolic Acid
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Kim JE, Cha JJ, Kim SW, Hong YA, Ko GJ, Kwon YJ
- KMID: 2268926
- Korean J Med.
- 2015 Dec;89(6):690-694.
- doi: 10.3904/kjm.2015.89.6.690
IgG4-related disease (IgG4-RD) is a group of fibro-inflammatory diseases affecting multiple organ systems, pathologically characterized by tissue infiltration with abundant IgG4-positive cells. We here report a case of IgG4-RD that... -
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- Mycophenolic Acid Induced Apoptosis in Human Jurkat Cells viathe Generation of Reactive Oxygen Species
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Lee DK, Lee HK, Choi SJ, Chung SY
- KMID: 1476276
- J Korean Surg Soc.
- 2008 Sep;75(3):149-155.
PURPOSE: Mycophenolic acid (MPA) is the active agent of mycophenolate mofetil (MMF), which is an immunosuppressive drug. MPA is a selective inhibitor of inosine monophosphate dehydrogenase. The aim of this... -
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- Effect of Cyclosporine, Mycophenolic Acid, and Rapamycin on the Proliferation of Rat Aortic Vascular Smooth Muscle Cells: in Vitro Study
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Moon JI, Kim YS, Kim EH, Kwon MS, Kim SI, Park K
- KMID: 2144935
- J Korean Soc Transplant.
- 1998 Nov;12(2):183-190.
Proliferative and obliterative arteriopathy resulting ischemic end organ dysfunction is the main histologic feature of chronic rejection after organ transplantation. This vascular narrowing and intimal hyperplasia produced by chronic rejection... -
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- Effects of Heme Oxygenase-1 Expression in Mycophenolic Acid Induced Apoptosis of Jurkat Cell Lines
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Lee HK, Choi SJ
- KMID: 2211964
- J Korean Surg Soc.
- 2010 Jun;78(6):343-349.
- doi: 10.4174/jkss.2010.78.6.343
PURPOSE: This study demonstrates that pharmacologic induction of heme oygenase-1 (HO-1) along with catalytic activation significantly modulated apoptosis of Jurkat cells induced by mycophenolic acid (MPA). METHODS: Cells were cultured with... -
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- Effects of Mycophenolic Acid on Oleic Acid- induced Rat Vascular Smooth Muscle Cell Proliferation
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Ahn HJ, Park J, Song JS, Ju MK, Kim MS, Ha H, Song KH, Kim YS
- KMID: 2211048
- J Korean Surg Soc.
- 2007 Mar;72(3):171-176.
PURPOSE: Vascular smooth muscle cell (VSMC) proliferation plays an important role in the development and progression of chronic allograft vasculopathy. Mycophenolic acid (MPA) inhibits various mesenchymal cell proliferation, and reactive... -
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- Mycophenolate Mofetil Overdose Induced Ventricular Tachycardia in a Patient with Systemic Lupus Erythematosus
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Kim JH, Chung H, Lee KA, Kim HR, Lee SH
- KMID: 2462832
- Korean J Med.
- 2019 Oct;94(5):455-458.
- doi: 10.3904/kjm.2019.94.5.455
Mycophenolate mofetil (MMF) is an immunosuppressive agent used to treat severe lupus, including lupus nephritis. Common adverse effects of MMF include gastrointestinal and hematological manifestations; however, cardiac toxicity in association... -
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- Treatment of Primary Glomerulonephritis
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Ihm CG
- KMID: 2267901
- Korean J Med.
- 2013 Jan;84(1):13-18.
Much progress has been made in the elucidation of potential pathogenetic mechanisms of glomerulonephritis such as anti-PLA2R autoantibody in membranous nephropathy and under-galactosylated IgA1 in IgA nephropathy as well as... -
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- Mycophenolic Acid Induced Apoptotic Signal Transduction in Molt-4 T-cells
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Choi SJ, Chung SY, Kim SK
- KMID: 2004711
- J Korean Surg Soc.
- 2002 Jan;62(1):8-17.
PURPOSE: Mycophenolic acid (MPA), a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH), is the active metabolite of the immunosuppressive drug, mycophenolate mofetil (MMF). MMF is used to prevent an immune-... -
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- Application of mycophenolate mofetil for immune-mediated hemolytic anemia in two dogs
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Park HJ, Lee DY, Song KH
- KMID: 1435836
- Korean J Vet Res.
- 2012 Sep;52(3):209-211.
A 5-year-old castrated male Shih-tzu dog and a 9-year-old intact female Schnauzer dog were presented with anorexia and depression. These 2 dogs were diagnosed based on which criteria as primary... -
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- Intra-individual variability of mycophenolic acid concentration according to renal function in liver transplant recipients receiving mycophenolate monotherapy
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Hwang S, Song GW, Jung DH, Park GC, Ahn CS, Moon DB, Ha TY, Kim KH, Lee SG
- KMID: 2371562
- Ann Hepatobiliary Pancreat Surg.
- 2017 Feb;21(1):11-16.
- doi: 10.14701/ahbps.2017.21.1.11
BACKGROUNDS/AIMS: Mycophenolate mofetil (MMF) has wide inter- and intra-individual variability of mycophenolic acid (MPA) after liver transplantation (LT). On this study, we aimed to analyse the intra-individual variability of MPA... -
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- Effects of Mycophenolic Acid and Rapamycin on Toll-like Receptor Expression in Hypoxic Human Proximal Tubular Epithelial Cells
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Lee D, Park J, Kim YS, Jeong HJ
- KMID: 2324139
- J Korean Soc Transplant.
- 2009 Jun;23(1):15-21.
BACKGROUND: Toll like receptor (TLR), an element of innate immunity, is upregulated by Ischemia/reperfusion (IR) injury and may be involved in adaptive immune response. Immunosuppressive agents may increase or attenuate... -
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- Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis
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Choi SJ, Lee HK, Kim NH, Chung SY
- KMID: 1445743
- J Korean Surg Soc.
- 2011 Oct;81(4):235-241.
- doi: 10.4174/jkss.2011.81.4.235
PURPOSE: This study demonstrated that apoptosis induced by mycophenolic acid (MPA) is mediated by mitochondrial membrane potential transition (MPT) changes in Jurkat cells. METHODS: Cell viability and MPT changes were measured... -
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- Oral Ulceration an Overlooked Complication of Mycophenolate Mofetil in a Renal Transplant Recipient
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Ahn SH, Min SK, Min SI, Kim SY, Kim SJ, Ha J
- KMID: 2324204
- J Korean Soc Transplant.
- 2011 Jun;25(2):113-115.
Mycophenolate mofetil (MMF) is being widely used as a maintenance imunosuppressive therapy in renal transplant patients. Myelotoxicity and gastrointestinal symptoms are the well-known adverse effects of this immunosuppressant. However, there... -
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- A Case of Disseminated Crytococcosis in a Patient with Systemic Lupus Erythematosus
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Jung HR, Kwon HH, Choe JY
- KMID: 2201972
- J Korean Rheum Assoc.
- 2010 Jun;17(2):194-199.
- doi: 10.4078/jkra.2010.17.2.194
Disseminated cryptococcosis mainly occurs in immunocompromised patients. It enters the body through the respiratory tract and spreads to the lungs, skin, liver and lymphoid organs. Among cryptococcosis, cryptococcal meningitis is... -
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- Effect of Mycophenolic Acid and Rapamycin on the Proliferation and Collagen Synthesis of the Vascular Smooth Muscle Cell of Rat
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Park J, Kim MS, Ha H, Huh KH, Kang SW, Kim HJ, Seo J, Moon JI, Kim YS, Park K
- KMID: 2003626
- J Korean Soc Transplant.
- 2003 Jun;17(1):1-6.
PURPOSE: Vascular smooth muscle cell (VSMC) proliferation and extracellular matrix protein accumulation play important roles in chronic allograft vasculopathy. Mycophenolic acid (MPA) or rapamycin (RPM) was reported to inhibit VSMC... -
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- The neuroprotective effect of mycophenolic acid via anti-apoptosis in perinatal hypoxic-ischemic brain injury
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Kim JY, Yang SH, Cha SH, Kim JY, Jang YC, Park KK, Kim JK, Chung HL, Seo ES, Kim WT
- KMID: 2278466
- Korean J Pediatr.
- 2007 Jul;50(7):686-693.
- doi: 10.3345/kjp.2007.50.7.686
PURPOSE: Mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), is a potent inhibitor of inosine-monophosphate dehydrogenase (IMPDH), a new immunosuppressive drug used. It was reported that MPA protected... -
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- Mechanisms Involved in the Inhibitory Effects of Mycophenolic Acid on the PDGF-induced Proliferation of Vascular Smooth Muscle Cells
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Park J, Ha H, Kim MS, Huh KH, Kim YS
- KMID: 2254308
- Korean J Nephrol.
- 2004 Jul;23(4):567-576.
BACKGROUND: Vascular smooth muscle cell (VSMC) proliferation plays an important role in the development and progression of chronic allograft vasculopathy as in atherosclerosis. We already reported that mycophenolic acid (MPA)... -
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- The use of immunosuppression in autoimmune hepatitis: A current literature review
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Cropley A, Weltman M
- KMID: 2412109
- Clin Mol Hepatol.
- 2017 Mar;23(1):22-26.
- doi: 10.3350/cmh.2016.0089
Autoimmune hepatitis (AIH) is an organ specific autoimmune condition which can manifest at any age of life. The heterogeneous nature of this condition means that great variation can be seen... -
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