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Investigation of experimental acute ischemic myocardium with a microdialysis apparatus

Park SD, Kim SM

  • KMID: 1686154
  • Korean J Thorac Cardiovasc Surg.
  • 1993 Jun;26(6):441-451.
No abstract available.
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Real-time Estimation of Mannitol-Induced Blood-Brain-Barrier Disruption by Microdialysis

Yoon SH, Cho KH, Cho KG, Ahn YM, Ahn YH

  • KMID: 1955349
  • J Korean Neurosurg Soc.
  • 1996 Sep;25(9):1761-1767.
We have done a study for the real-time changes of blood-brain-barrier disruption(BBBD) with brain cortical microdialysis induced by intra-carotid mannitol infusion and of cortical blood flow with laser Doppler flowmetry....
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In Vivo Microdialysis Measures of Extracellular Norepinephrine in the Rat Amygdala during Sleep-wakefulness

Park SP

Norepinephrine (NE)-containing locus ceruleus (LC) has been known to participate in the regulation of the sleep-wake cycle according to the differential firing rate. The aim of this study was to...
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Nitric Oxide Synthase Inhibition Alters Extracellular Glutamate Concentration after Global Cerebral Ischemia

Kil HY, Cho BJ, Piantadosi CA

No abstract available.
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Detection of Ammino Acids Using Microdialysis Technique and Changes of Amino Acid Concentrations in Experimentally Induced Nasal Allergy Model

Roh HJ, Suh JC, Lee HS, Goh EK, Chon KM

  • KMID: 2276389
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Apr;48(4):476-481.
BACKGROUND AND OBJECTIVES: The basic principle of microdialysis is to mimic the function of a capillary blood vessel by perfusing physiologic liquid implanted into the target tissue. Amino acids are...
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Characterization of Norepinephrine Release in Rat Posterior Hypothalamus Using in vivo Brain Microdialysis

Sung KW, Kim SY, Kim ON, Lee SB

  • KMID: 1614852
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):9-14.
In the present study, we used the microdialysis technique combined with high performance liquid chromatography (HPLC) and electrochemical detection to measure the extracellular levels of norepinephrine (NE) in the posterior...
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The Changes of Neurotransmitters in Central Sensitization after Peripheral Nerve Injury in Rats

Lee KY, Sohn SK, Kim DH

  • KMID: 2189865
  • J Korean Orthop Assoc.
  • 1998 Feb;33(1):168-176.
There has been much interest in the involvement of wind-up in the hyperalgesia and allodynia of chronic pain syndrome. For investigating the hehaviorml parallels of this wind-up phenomenon, it was...
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The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Kim DY, Chae JW, Lim CH, Heo BH, Park KS, Lee HG, Choi JI, Yoon MH, Kim WM

BACKGROUND: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action....
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Effect of Hypoxia-Ischemia on Striatal Monoamine Metabolism in Neonatal Rat Brains

Jee YH, Kim HG, Park WS, Chang YP

  • KMID: 1606964
  • J Korean Pediatr Soc.
  • 2003 Aug;46(8):789-794.
PURPOSE: We intended to evaluate the effect of hypoxia-ischemia on extracellular striatal monoamine metabolism in neonatal rat brains by in vivo microdialysis. METHODS: The right common carotid arteries of five or...
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Significance of Bioelectrical Impedance Change after Ischemia and Reperfusion Injury in Liver and What it Causes?

Yun SS

PURPOSE: Ischemia and reperfusion (I/R) injury is a major cause of hepatic failure after liver surgery, but there is no direct method to monitor it in real-time (like an ECG...
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The Effects of Repeated Toluene Exposure on Amino Acid Neurotransmitters in the Rat Brain

Kim HK, Baeck SK, Ryu SJ, Kim IS

  • KMID: 2228770
  • Korean J Crit Care Med.
  • 1998 Jun;13(1):33-42.
Introduction: It was aimed to investigate the effect of chronic toluene exposure on amino acid neurotransmitters in the rat brain, corpus striatum. METHODS: Twenty four male Sprague-Dawley rats were divided...
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Changes in Concentration of Extracellular Aspartate and Glutamate During Cortical Spreading Depression in the Rat Cerebral Cortex

Song JH, Park YK, Chung YG, Chung HS, Suh JK, Lee KC, Lee HK

  • KMID: 2018871
  • J Korean Neurosurg Soc.
  • 1996 Feb;25(2):242-251.
The author has examined the effect of cortical spreading depression(CSD) on the changes in extracellular concetration of aspartate and glutamate in the neocortex of anesthetized rats using microdialysis and high...
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The Time Course of the Changes in Lactate Produced by Incisions in the Rat

Cha YD, Lee HS, Han JU, Jung JK, Lee CS, Shin SH, Lim HK, Kim TJ

BACKGROUND: It is well known that the level of lactate increases in wounds, which is not necessarily caused by a limitation of oxygen delivery, so may not primarily indicate ischemia....
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Combination of In Vivo [¹²³I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Park SH, Song YS, Moon BS, Lee BC, Park HS, Kim SE

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [¹²³I]FP-CIT assesses changes in synaptic DA availability when endogenous...
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Effect of Hyperglycemia on Glutamate , Glycine and Aspartate Concentrations during Peri-ischemic Periods in the Rabbit Hippocampus

Choi KT

Hyperglycemia has repeatedly been shown to exacerbate the neurologic injury produced by episodes of global cerebral ischemia. Under hypoxic conditions, glucose may be metabolized to glutamate, a known neurotoxin which...
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Impaired Cation Transport May Lead to Bioelectrical Impedance Changes during Hepatic Ischemia

Cui ML, Ahn HS, Kim JY, Lee DS, Kim HJ, Yun SS

PURPOSE: Ischemia and reperfusion (I/R) injury is a major cause of hepatic failure after liver surgery, but there is no direct method to monitor it in real-time (like an electrocardiogram...
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Monoaminergic Activity by Drugs Acting on Adrenergic alpha2-receptors in Rat Hippocampus and Primary Visual Cortex

Kim HG, Lee YC, Paik KC, Lim MH, Kim HW, Kang BJ

  • KMID: 2286867
  • Korean J Psychopharmacol.
  • 2004 Sep;15(3):371-379.
OBJECTIVE: The aim of the this study was to compare the effects of clonidine (a alpha2-adrenoceptor and imidazoline receptor agonist), yohimbine (a selective alpha2-adrenoceptor antagonist) and idazoxan (a alpha2-adrenoceptor and...
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Effects of High Fat Diet on Lipolysis in Skeletal Muscle and Adipose Tissue in Rats

Kim CH, Chung YE, Lee SJ, Park JY, Hong SK, Kim HK, Suh KI, Lee KU

  • KMID: 1767980
  • J Korean Diabetes Assoc.
  • 2000 Dec;24(6):641-651.
BACKGROUND: It has been hypothesized that increased fat oxidation reduces glucose utilization in skeletal muscle, and is responsible for the insulin resistance associated with obesity or high-fat feeding. In contrast,...
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Effect of serotonin uptake inhibitors on serotonin metabolism in the hypothalamus of freely moving rats

Song YS, Yoon SN, Jung DS, Yoo SH, Ryu HK, Kim HG

  • KMID: 1581021
  • Korean J Physiol Pharmacol.
  • 2000 Dec;4(6):439-444.
Tricyclic antidepressant clomipramine or selective serotonin reuptake inhibitors (SSRIs) have been commonly used for the treatment of premature ejaculation. In the present study, we analyzed the concentrations of serotonin and 5-hydroxyindoleacetic acid (5-HIAA)...
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Comparison of the Dopamine Response in the Rat Prefrontal Cortex Induced by Irregular and Regular Electrical Stimuli

Chung YC, Moon SG, Eun HB, Hwang IK, Lim CW, Han JH

  • KMID: 2037058
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):239-245.
OBJECTIVE: In general, it is known that repetitive regular stimuli induce tolerance and repetitive irregular stimuli induce sensitization. We sought to determine the dopamine response in the rat prefrontal cortex...
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