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Intestinal mastocytosis and goblet cell hyperplasia in BALB/c and C3H mice infected with Neodiplostomum seoulense

Chai JY, Kim TK, Cho WH, Seo M, Kook J, Guk SM, Lee SH

Mucosal mast cell (MMC) and goblet cell (GC) responses were observed in the small intestine of two strains of mice (BALB/c and C3H) infected with Neodiplostamum seoulense, and their roles...
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Susceptibility of several strains of mice to Echinostoma hortense infection

Lee KJ, Park SK, Im JA, Kim SK, Kim GH, Kim GY, Yang EJ, Ryang YS

Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed...
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Viscerotropic growth pattern of Leishmania tropica in BALB/c mice is suggestive of a murine model for human viscerotropic leishmaniasis

Mahmoudzadeh-Niknam H, Kiaei SS, Iravani D

Leishmania (L.) tropica is a causative agent of cutaneous leishmaniasis, and occasionally of visceral or viscerotropic leishmaniasis in humans. Murine models of Leishmania infection have been proven to be useful...
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Leishmania tropica infection, in comparison to Leishmania major, induces lower delayed type hypersensitivity in BALB/c mice

Mahmoudzadeh-Niknam H, Kiaei SS, Iravani D

Leishmania tropica and L. major are etiologic agents of human cutaneous leishmaniasis. Delayed type hypersensitivity (DTH) is an immunologic response that has been frequently used as a correlate for protection...
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Thymic epithelial cells of severe combined immunodeficiency (SCID) mice

Lee I, Yu E, Ikehara S

To characterize thymic epithelial cells of SCID (severe combined immunodeficiency) mice in comparison with those of Balb C mice, we did an immunohistochemical study using cortical and medullary epithelial cell...
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Genotype and animal infectivity of a human isolate of Cryptosporidium parvum in the Republic of Korea

Guk SM, Yong TS, Park SJ, Park JH, Chai JY

Cryptosporidium parvum oocysts were isolated from a child suffering from acute gastroenteritis and successfully passaged in a calf and mice (designated hereafter SNU-H1) in the Republic of Korea; its molecular...
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Antibody Responses in Sera of Different Mouse Strains Experimentally Infected with Neodiplostomum seoulense

Han ET, Chen JH, Chai JY

To examine humoral immune responses in the host, we measured serum antibody levels in different strains of mice (ICR, BALB/c, and C3H) experimentally infected with Neodiplostomum seoulense. Specific IgG antibody...
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Effects of iNOS inhibitor on IFN-gamma production and apoptosis of splenocytes in genetically different strains of mice infected with Toxoplasma gondii

Kang KM, Lee GS, Lee JH, Choi IW, Shin DW, Lee YH

To evaluate the role of nitric oxide (NO) in IFN-gamma production and apoptosis of splenocytes in genetically different strains of mice with toxoplasmosis, BALB/c (a toxoplasmosis resistant strain) and C57BL/6...
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Experimental Murine Fascioliasis Derives Early Immune Suppression with Increased Levels of TGF-beta and IL-4

Chung JY, Bae YA, Yun DH, Yang HJ, Kong Y

  • KMID: 1792122
  • Korean J Parasitol.
  • 2012 Dec;50(4):301-308.
In fascioliasis, T-helper 2 (Th2) responses predominate, while little is known regarding early immune phenomenon. We herein analyzed early immunophenotype changes of BALB/c, C57BL/6, and C3H/He mice experimentally infected with...
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Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinoma cells

Cho KH, Lee HS, Ku SK

The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a...
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The Route of Leishmania tropica Infection Determines Disease Outcome and Protection against Leishmania major in BALB/c Mice

Mahmoudzadeh-Niknam H, Khalili G, Abrishami , Najafy A, Khaze V

Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. The...
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Immunohistochemical Study of the Pancreatic Endocrine Cells in the BALB/c mice: An Unique Distributional Pattern of Glucagon

Ku SK, Lee HS, Lee JH

  • KMID: 1095117
  • J Vet Sci.
  • 2002 Sep;3(3):167-173.
The regional distribution and relative frequency of insulin-, glucagon-, somatostatin- and pancreatic polypeptide (PP)-producing endocrine cells in the pancreas of BALB/c mouse were investigated by immunohistochemical method. The pancreas of...
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Comparison of carbohydrate moieties of sparganum proteins of the snake, mouse and those of adult worm

Yang HJ

The carbohydrate moieties of larval sparganum proteins in two different species, the snakes, Elaphe rufodorsata, the Balb/c mouse and those of the adult worm, Spirometra erinacei, were compared using five...
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Effect of Pyrimethamine on DNA Synthesis of Germ Cells in Mice Testis

Lee SK, Lee JS, Kim KA, Cho JS

  • KMID: 1662201
  • Korean J Urol.
  • 1995 Apr;36(4):386-391.
Pyrimethamine(PYR) produces reversible infertility in mice. The antifertility effect of PYR is due to its antifolate action. PYR causes male infertility in Balb C mice in a dose dependent manner....
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Depressed Neuronal Growth Associated Protein (GAP)-43 Expression in the Small Intestines of Mice Experimentally Infected with Neodiplostomum seoulense

Pyo KH, Kang EY, Jung BK, Moon JH, Chai JY, Shin EH

Neodiplostomum seoulense (Digenea: Neodiplostomidae) is an intestinal trematode that can cause severe mucosal pathology in the small intestines of mice and even mortality of the infected mice within 28 days...
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Towards developing a diagnostic regimen for the treatment follow-up of Trypanosoma brucei gambiense

Mbati PA, Hirumi K, Inoue N, Situakibanza NH, Hirumi H

BALB/c mice infected with a high virulent strain of Trypanosoma brucei gambiense IL3707 were treated intraperitoneally (ip) with either Melarsoprol (Mel-B) or PSG(+) buffer as controls. The mice were subsequently...
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Gene Expression Profiles in Genetically Different Mice Infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU

Ismail HA, Quan JH, Wei Z, Choi IW, Cha GH, Shin DW, Lee YH, Song CJ

Toxoplasma gondii can modulate host cell gene expression; however, determining gene expression levels in intermediate hosts after T. gondii infection is not known much. We selected 5 genes (ALDH1A2, BEX2,...
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Aureobasidium-Derived Soluble Branched (1,3-1,6) beta-Glucan (Sophy beta-glucan) Enhances Natural Killer Activity in Leishmania amazonensis-Infected Mice

Yatawara L, Wickramasinghe S, Nagataki M, Takamoto M, Nomura H, Ikeue Y, Watanabe Y, Agatsuma T

The beta-glucans derived from yeast cell walls have been reported for having many immunomodulatory activities in vivo and in vitro. In this study, Aureobasidium-derived soluble branched (1,3-1,6) beta-glucan (Sophy beta-glucan)...
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Identification of novel Leishmania major antigens that elicit IgG2a response in resistant and susceptible mice

Mohammadi , Zeinali M, Ardestani , Kariminia

Experimental murine models with high, intermediate and low levels of genetically based susceptibility to Leishmania major infection reproduce almost entire spectrum of clinical manifestations of the human disease. There are...
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Establishment of BALB/c mice model infected with Helicobacter pylori

Jin DZ, Jung HC, Kim JM, Kim JS, Song IS, Kim CY

  • KMID: 760335
  • Korean J Intern Med.
  • 1999 Jul;14(2):55-63.
OBJECTIVES: Considering the geographic differences in the prevalence of virulence factors such as CagA or VacA of H. pylori isolated from Korean adults compared with those from western...
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