- Effects of Topical Application of Halofuginone on Wound Healing
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Shin DJ, Kim DW, Lee SJ, Kim JC
- KMID: 1863715
- Korean J Dermatol.
- 2000 Mar;38(3):305-313.
BACKGROUND: During normal wound healing the formation of scars and fibrous tissue occurs, which consists largely of collagen fibril, but excessive fibrosis and scar formation become clinical problems. Collagen remodelling during scar... -
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- Anti-inflammatory and Anti-pruritic Effects of Portulaca oleracea L. Extract Using In Vitro and In Vivo Inflammation Model: LPS-treated Raw264.7 Cells, Keratinocytes, NC/Nga Mice and Hairless SKH-1 Mice
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- KMID: 2299502
- Korean J Asthma Allergy Clin Immunol.
- 2011 Sep;31(3):199-206.
BACKGROUND: Portulaca oleracea L. is known to have detoxification and antibacterial effects. Inflammatory responses in LPS-treated Raw264.7 cells include the secretions of NO, PGE2 and numerous cytokines. Atopic dermatitis is... -
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- The Studies on the Factors Related to Normal Hair Growth During Postnatal Growth Periods in C57BL/6N, Hairless and Alopecia Areata Mice Model
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Lee MW, Oh CH, Kwon J, Song CH, Lee CH
- KMID: 2283200
- Korean J Phys Anthropol.
- 2005 Mar;18(1):13-27.
We have examined the factors related to hair growth regulation during postnatal growth periods in C57BL/6N, hairless and alopecia areata mice model. We first studied the number, localization and granulation... -
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- Aspectual Comparison of the Skin Changes in Hairless Mice According to the Aging Type
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Choi KH, Kim YC, Kim BH
- KMID: 2312063
- Lab Anim Res.
- 2010 Jun;26(2):173-180.
The purpose of this study was to compare the skin changes in female SKH-1 hairless mice between UVB irradiated photo-aged group and endogenous aged group. The UVB irradiation and endogenous... -
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- Early diagnosis of radiodermatitis using lactate dehydrogenase isozymes in hairless mice (SKH1-hr)
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Cho SK, Kim WD
- KMID: 1431407
- Lab Anim Res.
- 2012 Dec;28(4):239-244.
- doi: 10.5625/lar.2012.28.4.239
In this study, we evaluate a method for the early diagnosis of radiodermatitis for use in the prevention and therapy of this condition. Hairless mice (SKH1-hr) were used to study... -
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- Dietary effect of green tea extract on hydration improvement and metabolism of free amino acid generation in epidermis of UV-irradiated hairless mice
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Choi S, Shin J, Lee B, Cho Y
- KMID: 2357129
- J Nutr Health.
- 2016 Oct;49(5):269-276.
- doi: 10.4163/jnh.2016.49.5.269
PURPOSE: Ultraviolet (UV) irradiation decreases epidermal hydration, which is maintained by reduction of natural moisturizing factors (NMFs). Among various NMFs, free amino acids (AA) are major constituents generated by filaggrin... -
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- The Effect of Alpha Hydroxy Acids (Glycolic and Lactic acid) on Hairless Mouse Skin
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Kim SJ, Park JH, Park K, Lee SC, Chun IK, Won YH
- KMID: 2360348
- Ann Dermatol.
- 1997 Oct;9(4):253-257.
- doi: 10.5021/ad.1997.9.4.253
BACKGROUND: Alpha hydroxy acid containing products are now widely used as cosmetics or skin protectives because it is believed to have a favorable effect against the aging process of skin. OBJECTIVE:... -
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- Barrier Rcovery after Topically Applied Desoxymethasone Ontment, Vaseline and Hydrobase on Benzalkonium Chloride-irritated Hairless Mice Skin
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Ahn SK, Choi EH, Shaojun J, Hwang SM, Lee SH
- KMID: 2303423
- Korean J Dermatol.
- 1998 Oct;36(5):820-826.
BACKGROUND: Topical irritants disrupt the cutaneous permeability barrier through the removal of stratum comeum lipids. This perturbation of barrier integrity stimulates a variety of homeostatic repair responses that ultimately result... -
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- The Effect of High Dose Systemic Steroid and its Long-term Usage on the Skin Barrier of Hairless Mice
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Lee JW, Bak H, Ahn SK, Choi EH, Lee SH
- KMID: 2302913
- Korean J Dermatol.
- 2004 Mar;42(3):281-289.
BACKGROUND: Prolonged exposure of topical and systemic corticosteroid to skin can result in well-recognized cutaneous abnormalities including cutaneous atrophy, easy bruisibility, increased skin fragility, and increased risk of infection. Skin... -
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- Dietary effect of green tea extract on epidermal levels of skin pH related factors, lactate dehydrogenase protein expression and activity in UV-irradiated hairless mice
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Lee B, Kim J, Hwang J, Cho Y
- KMID: 2209843
- J Nutr Health.
- 2016 Apr;49(2):63-71.
- doi: 10.4163/jnh.2016.49.2.63
PURPOSE: Skin pH, an indicator of skin health, is maintained by various organic factors, which include lactate, free amino acid (FAA), and free fatty acid (FFA). As skin ages or... -
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- The Effect of Solvents Polarity on the Skin Barrier in Hairless Mice
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Choi TJ, Yoon DH, Kim HO, Kim CW
- KMID: 2085947
- Korean J Dermatol.
- 1997 Aug;35(4):660-666.
BACKGROUND: The stratom corneum lipids, responsible for the epidermal water bar rier, consist mainly of ceramides, cholesterol and free fatty acids. However, little has been studied about the effects of... -
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- Safety Evaluation of Stamp Type Digital Microneedle Devices in Hairless Mice
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Park KY, Jang WS, Lim YY, Ahn JH, Lee SJ, Kim CW, Kim SE, Kim BJ, Kim MN
- KMID: 2265970
- Ann Dermatol.
- 2013 Feb;25(1):46-53.
- doi: 10.5021/ad.2013.25.1.46
BACKGROUND: Microneedles provide a minimally invasive means to transport molecules into the skin. A number of specific strategies have been employed to use microneedles for transdermal delivery. OBJECTIVE: The purpose of... -
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- Oral Administration of Glycine and Leucine Dipeptides Improves Skin Hydration and Elasticity in UVB-Irradiated Hairless Mice
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Park JI, Lee JE, Shin HJ, Song S, Lee WK, Hwang JS
- KMID: 2389385
- Biomol Ther.
- 2017 Sep;25(5):528-534.
- doi: 10.4062/biomolther.2017.089
Placenta is a special organ that contains many nutrients such as growth factors, minerals, and bioactive peptides. Dipeptides of glycine and leucine are major components of porcine placenta extracts (PPE)... -
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- Folliculitis after Tanning Oil Application
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Lee SY, Ji JH, Bak H, Ahn SK
- KMID: 2088080
- Korean J Dermatol.
- 2010 Sep;48(9):780-782.
Folliculitis is an inflammatory disease that has various causes. It has been widely reported to be caused by exposure to industrial oil such as cutting oil and diesel oil. A... -
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- The Study on the Ultraviolet-B Blocking Effect of Sunscreens in the Epidermal Langerhans Cells of Hairless Mice
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Won YH, Yoo YE, Lee SC, Kim YP, Chun IK
- KMID: 2361355
- Ann Dermatol.
- 1995 Oct;7(4):288-294.
- doi: 10.5021/ad.1995.7.4.288
BACKGROUND: Sunscreens have been used widely to prevent the photosensitive skin diseases, skin cancer, and skin aging. However, no sunscreen blocks all kinds of effects caused by ultraviolet light(UVL), and... -
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- The Effect of Topical Application of Heparin with Microneedling on Skin Flap Survival
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Yang E, Kim SW
- KMID: 1920338
- J Korean Soc Plast Reconstr Surg.
- 2009 May;36(3):254-261.
PURPOSE: The objective of this study is to evaluate the heparin effect for a viability of random-pattern dorsal flap in hairless mouse. METHODS: A caudally-based random dorsal flap, measuring 1.5 x... -
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- The Effects of Topical Glycolic Acid on the Expression of Epidermal Cytokines and Epidermal Calcium Gradient of Hairless Mice
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Ko JY, Jeong SK, Lee SH, Lee CW
- KMID: 2302914
- Korean J Dermatol.
- 2004 Mar;42(3):290-299.
BACKGROUND: Although the topical application of glycolic acid (GA) could possibly exert some effects on the normal epidermal permeability function, the exact effects and its mechanism of action have not... -
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- The Effect of Ultraviolet B Irradiation on the Skin Barrier Function in Hairless Mice
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Yoon DH, Kim HO, Kim TY, Kim CW, Song KY
- KMID: 2085799
- Korean J Dermatol.
- 1995 Aug;33(4):669-678.
BACKGROUND: Stratum corneum lipids serve as a water retainer as well as permeability barrier by forming a multi-lamellae structure in the stratum corneum. The major constituent of these lipids, ceramides,... -
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- Photoprotective Effect of Various Sunscreens Against Ultraviolet B - induced Chronic Skin Damage
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Choi HJ, Hann SK, Park YK
- KMID: 2115930
- Korean J Dermatol.
- 1995 Feb;33(1):8-18.
BACKGROUND: Chronic exposure to ultraviolet radiation(UVE) nduces photoaging characterized by dry, deeply wrinkled, inelastic, leathery, and irregulaity pigmented skin. UVR also induces solar keratosis and carcinoma, and is a contributing... -
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- Water-Impermeable Occlusion Effect to Intercorneocyte Lipid Layers in Hairless Mice
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Jiang S, Youl S, Lee SH
- KMID: 2360400
- Ann Dermatol.
- 1997 Apr;9(2):116-125.
- doi: 10.5021/ad.1997.9.2.116
BACKGROUND: Stratum corneum lipids are arranged as intercellular membrane bilayers presumed to mediate the epidermal permeability barrier. Acute disruption in barrier function will initiate epidermal lipid synthesis, which can be... -
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