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Comparative Viral Metagenomics of Environmental Samples from Korea

Kim MS, Whon TW, Bae JW

The introduction of metagenomics into the field of virology has facilitated the exploration of viral communities in various natural habitats. Understanding the viral ecology of a variety of sample types...
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Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era

Kim M, Lee KH, Yoon SW, Kim BS, Chun J, Yi H

Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the...
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Oral Metagenomic Analysis Techniques

Chung SK

The modern era of microbial genome analysis began in earnest in the 2000s with the generalization of metagenomics and gene sequencing techniques. Studying complex microbial community such as oral cavity...
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Application of Metagenomic Techniques: Understanding the Unrevealed Human Microbiota and Explaining the in Clinical Infectious Diseases

Kim W

Uncultured microorganisms comprise the majority of the planet's biological diversity. In many environments, as many as 99% of the microorganisms cannot be cultured by standard techniques, and the uncultured fraction...
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Bioprospecting Potential of the Soil Metagenome: Novel Enzymes and Bioactivities

Lee MH, Lee SW

The microbial diversity in soil ecosystems is higher than in any other microbial ecosystem. The majority of soil microorganisms has not been characterized, because the dominant members have not been...
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Microbiome Research in Atopic Dermatitis

Kim MH

Atopic dermatitis (AD) is a representative allergic disease that is accompanied with high disease prevalence and considerable socioeconomic burden. While the pathophysiology is largely unknown, the role of microbes in...
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Statistical Analysis of Metagenomics Data

Calle ML

Understanding the role of the microbiome in human health and how it can be modulated is becoming increasingly relevant for preventive medicine and for the medical management of chronic diseases....
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Evaluation of 16S rRNA Databases for Taxonomic Assignments Using a Mock Community

Park SC, Won S

Taxonomic identification is fundamental to all microbiology studies. Particularly in metagenomics, which identifies the composition of microorganisms using thousands of sequences, its importance is even greater. Identification is inevitably affected...
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Our Genome and Our other Genome: Understanding humans as Symbionts with Microbes

Kim HS

One of the most significant discoveries in life sciences and medicine in recent years is that we humans are symbionts with a large number of microbes. These microbes reside on...
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Human microbiome studies in Korea

Choi S, Cho SH, Yi H

During the second half of the 2000s, the significant impact of human microbiome on human diseases and health conditions was found. Since the Human Microbiome Project, many microbiome studies have...
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Human Resistome Study with Metagenomic Sequencing Data

Shin JH, Rho M

With the introduction of synthetic antibiotics, many lives including humans and animals have been saved against bacterial infection. An increasing level of antibiotics use, however, raises serious problems of multi-drug...
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An Advanced Understanding of Uterine Microbial Ecology Associated with Metritis in Dairy Cows

Jeon SJ, Galvão KN

Metritis, the inflammation of the uterus caused by polymicrobial infections, is a prevalent and costly disease to the dairy industry as it decreases milk yield, survival, and the welfare of...
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Microbiome of the upper airway focusing on chronic rhinosinusitis and allergic rhinitis

Hong SN, Park P, Cho SH, Kim DY

The human microbiome is a collection of microbial species and their associated genomes that live on and in the body. Recent advances in molecular biology methods have revolutionized microbiome analysis...
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Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood

Park JY, Choi J, Lee Y, Lee JE, Lee EH, Kwon HJ, Yang J, Jeong BR, Kim YK, Han PL

Emerging evidence has suggested that the gut microbiota contribute to brain dysfunction, including pathological symptoms of Alzheimer disease (AD). Microbiota secrete membrane vesicles, also called extracellular vesicles (EVs), which contain...
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Human Population Admixture in Asia

Xu S

Genetic admixture in human, the result of inter-marriage among people from different well-differentiated populations, has been extensively studied in the New World, where European colonization brought contact between peoples of...
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MitGEN: Single Nucleotide Polymorphism DB Browser for Human Mitochondrial Genome

Park HS, Lee SU

  • KMID: 2053082
  • Genomics Inform.
  • 2004 Sep;2(3):147-148.
Recently completed mitochondrial genome databses from public resources provide us with a better understanding of individual mitochondrial genomes for population genomics. By determining the substitution rate of the genomic sequences,...
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Lung Microbiome Analysis in Steroid-NaÑ—ve Asthma Patients by Using Whole Sputum

Jung JW, Choi JC, Shin JW, Kim JY, Park IW, Choi BW, Park HW, Cho SH, Kim K, Kang HR

BACKGROUND: Although recent metagenomic approaches have characterized the distinguished microbial compositions in airways of asthmatics, these results did not reach a consensus due to the small sample size, non-standardization of...
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Understanding Disease Susceptibility through Population Genomics

Han S, Lee J, Kim S

Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression...
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Peri-implant disease: what we know and what we need to know

Valente NA, Andreana S

Peri-implant disease is a serious problem that plagues today's dentistry, both in terms of therapy and epidemiology. With the expansion of the practice of implantology and an increasing number of...
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Current Status and Future Promise of the Human Microbiome

Kim BS, Jeon YS, Chun J

  • KMID: 2315410
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2013 Jun;16(2):71-79.
The human-associated microbiota is diverse, varies between individuals and body sites, and is important in human health. Microbes in human body play an essential role in immunity, health, and disease....
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