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Therapeutic Strategies in Malformations of Cortical Development: Overview

Ko TS

  • KMID: 1816471
  • J Korean Epilepsy Soc.
  • 2000 Dec;4(2):94-100.
No abstract available.
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Malformations of cortical development: genetic mechanisms and diagnostic approach

Lee J

Malformations of cortical development are rare congenital anomalies of the cerebral cortex, wherein patients present with intractable epilepsy and various degrees of developmental delay. Cases show a spectrum of anomalous...
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Classification of Malformations of Cortical Development Clinical Features and Imaging Findings

Kim SH

  • KMID: 1816470
  • J Korean Epilepsy Soc.
  • 2000 Dec;4(2):87-93.
No abstract available.
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Bilateral Cerebellar Cortical Dysplasia without Other Malformations: A Case Report

Oh JS, Ahn KJ, Kim JY, Lee SJ, Park JM

Recent advances in MRI have revealed congenital brain malformations and subtle developmental abnormalities of the cerebral and cerebellar cortical architecture. Typical cerebellar cortical dysplasia as a newly categorized cerebellar malformation,...
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Electrobehavioral and Pathological Characteristics in Cerebral Cortical Dysplasia Induced by External Irradiation in the Rat

Choi HY

  • KMID: 1547687
  • J Korean Neurosurg Soc.
  • 2000 Jul;29(7):861-867.
No abstract available.
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Molecular genetic decoding of malformations of cortical development

Lim JS, Lee JH

Malformations of cortical development (MCD) cover a broad spectrum of developmental disorders which cause the various clinical manifestations including epilepsy, developmental delay, and intellectual disability. MCD have been clinically classified...
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A Case of Tuberous Sclerosis with Hemimegalencephaly

Lee YJ, Lee EH, Jung MH, Yum MS, Ko TS

  • KMID: 2329434
  • J Korean Child Neurol Soc.
  • 2009 Nov;17(2):231-236.
Hemimegalencephaly and tuberous sclerosis complex are distinct and rare conditions which are characterized by malformations of cortical developments. Hemimegalencephaly is a cerebral malformation of unknown pathophysiology characterized by asymmetry of...
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Normal and Disordered Formation of the Cerebral Cortex : Normal Embryology, Related Molecules, Types of Migration, Migration Disorders

Lee JY

The expansion and folding of the cerebral cortex occur during brain development and are critical factors that influence cognitive ability and sensorimotor skills. The disruption of cortical growth and folding...
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Focal Cortical Dysplasia in Pediatric Epilepsy

Choi SA, Kim KJ

Focal cortical dysplasia (FCD) is the most common cause of intractable focal epilepsy in children undergoing epilepsy surgery. In these patients, seizures usually develop in early childhood and are often...
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Bilateral Frontal Polymicrogyria: An Autopsy Case Report

Chun YK, Choi JS, Chi JG

Bilateral frontal polymicrogyria is a recently recognized syndrome characterized by symmetric polymicrogyria of both frontal lobes that presents with delayed motor and language development, spastic quadriparesis, and variable mental retardation....
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Cortical Dysplasia of Brain: 2 Autopsy Cases

Kwon TJ, Kim YH, Kim DH

  • KMID: 2082668
  • Korean J Leg Med.
  • 2006 Oct;30(2):123-128.
Cortical dysplasia is used to designate any cerebral developmental malformation, and encompass a spectrum of pathologic changes from mild cortical disruption to more severe pattern of cortical dyslamination with large...
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A Case of Neurofibromatosis Type 1 with Cortical Dysplasia

Lee JS, Kim SH, Kim HM, Park SY, Lee JH, Chae JH, Kim KJ, Hwang YS, Kim IO

  • KMID: 2329330
  • J Korean Child Neurol Soc.
  • 2005 Nov;13(2):276-281.
Neurofibromatosis type 1(NF1) is the most common neurocutaneous syndrome which has an autosomal dominant pattern of inheritance. The NF1 gene is located on chromosome 17q11.2 and encodes for neurofibromin known...
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A case of schizencephaly with heterotopic gray matter that was only manifested a seizure attack

Shin SH, Kim JH, Yang IK

  • KMID: 1691977
  • J Korean Neuropsychiatr Assoc.
  • 1991 Jul;30(4):782-786.
No abstract available.
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Epilepsy : Surgical Treatment

Hong SC

Interest in epilepsy surgery is getting more and more increased with the development of computer-EEG and neuroimaging technique. There is a definite subgroup of intractable epilepsy patients who can be...
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Rolandic Cortical Dysplasia: Case Report

Kim HI, Jung CK, Choi HY, Palmini A, Lee MC, Lee JC

  • KMID: 1954678
  • J Korean Neurosurg Soc.
  • 1994 Jun;23(6):700-706.
The advent of MRI enables us to make an in-vivo diagnosis of cortical dysplastic lesions which are highly epileptogenic and show the variety of seizure patterns. Authors report a case...
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The Surgical and Cognitive Outcomes of Focal Cortical Dysplasia

Choi SA, Kim KJ

Focal cortical dysplasia (FCD) is the major cause of intractable focal epilepsy in childhood leading to epilepsy surgery. The overall seizure freedom after surgery ranges between 50–75% at 2 years...
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Pathological Classification of Focal Cortical Dysplasia (FCD) : Personal Comments for Well Understanding FCD Classification

Kim SH, Choi J

In 2011, the International League against Epilepsy (ILAE) proposed a first international consensus of the classification of focal cortical dysplasia (FCD). This FCD classification had been widely used in worldwide....
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Disorganized Foliation of Unilateral Cerebellar Hemisphere as Cerebellar Cortical Dysplasia in Patients with Recurrent Seizures: A Case Report

Baek HJ

We present a rare case of abnormal foliation for one cerebellar hemisphere on MR imaging, showing vertically-oriented folia. Foliation of contralateral cerebellar hemisphere and other structures in the posterior fossa...
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Surgical Experience of Cortical Dysplasia in Patient with Intractable Epilepsy

Shin HS, Lee CS, Hwang YS, Kim SJ, Kim HD, Park SK

  • KMID: 1549041
  • J Korean Neurosurg Soc.
  • 1998 Oct;27(10):1440-1444.
Cortical dysplasia is a rare developmental disorder developed from a defect of neuronal migration. It is characterized by disruption of the normal cortical lamination by abnormal large nerve cells and...
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Role of Apoptosis in Development of Experimental Rat Cerebral Cortical Dysplasia

Lee YJ, Chung CK

  • KMID: 2181951
  • J Korean Epilepsy Soc.
  • 2003 Dec;7(2):101-107.
Microgyria is one type of cortical dysplasia with dyslaminations and anomalous cell densities, which could be produced experimentally. In a normal rat cortical development, overproduced neuroblasts gradually die by apoptosis....
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