- Molecular Mechanism of Reactive Oxygen Species-dependent ASK1 Activation in Innate Immunity
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Yamauchi S, Noguchi T, Ichijo H
- KMID: 2054252
- Immune Netw.
- 2008 Mar;8(1):1-6.
- doi: 10.4110/in.2008.8.1.1
Apoptosis signal-regulating kinase 1 (ASK1), a mitogen- activated protein kinase kinase kinase, plays pivotal roles in stress responses. In addition, ASK1 has emerged as a key regulator of immune responses... -
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- Dyrk1A Positively Stimulates ASK1-JNK Signaling Pathway during Apoptotic Cell Death
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Choi HK, Chung KC
- KMID: 2165344
- Exp Neurobiol.
- 2011 Mar;20(1):35-44.
- doi: 10.5607/en.2011.20.1.35
Dual-specificity tyrosine (Y)-phosphorylation-regulated protein kinase 1A (Dyrk1A) is the mammalian homologue of Drosophila melanogaster minibrain and its human gene is mapped to the Down syndrome critical region of chromosome 21.... -
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- ASK1 is Involved in EBV LMP1-induced NF-kappaB Activation
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Song YJ
- KMID: 1434774
- J Bacteriol Virol.
- 2012 Mar;42(1):63-68.
- doi: 10.4167/jbv.2012.42.1.63
Epstein-Barr virus (EBV) latent infection transforms B lymphocytes into proliferating lymphoblastoid cell lines (LCLs). EBV latent infection membrane protein 1 (LMP1) is required for EBV-mediated B lymphocyte transformation, and LMP1-induced... -
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- Apoptosis signal-regulating kinase 1 (ASK1) is linked to neural stem cell differentiation after ischemic brain injury
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Song J, Cho KJ, Cheon SY, Kim SH, Park KA, Lee WT, Lee JE
- KMID: 2154288
- Exp Mol Med.
- 2013 Dec;45(12):e69.
Neural stem cells (NSCs) have been suggested as a groundbreaking solution for stroke patients because they have the potential for self-renewal and differentiation into neurons. The differentiation of NSCs into... -
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- Involvement of miR-Let7A in inflammatory response and cell survival/apoptosis regulated by resveratrol in THP-1 macrophage
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Song J, Jun M, Ahn MR, Kim OY
- KMID: 2390139
- Nutr Res Pract.
- 2016 Aug;10(4):377-384.
- doi: 10.4162/nrp.2016.10.4.377
BACKGROUND/OBJECTIVES: Resveratrol, a natural polyphenol, has multiple functions in cellular responses including apoptosis, survival, and differentiation. It also participates in the regulation of inflammatory response and oxidative stress. MicroRNA-Let-7A (miR-Let7A),... -
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