- Growth Inhibition of Leukemic Cells by C-myb Antisense Oligos: Use of Simulational Target Site Search and Enhanced Delivery of Antisense Oligos by Cationic Liposomes
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Moon IJ, Park JG
- KMID: 2083373
- Korean J Hematol.
- 1999 May;34(2):241-251.
BACKGROUND: Aberrant expression of c-myb gene is often detected in transformed leukemic cells. Inhibition of c-myb expression by antisense oligos was shown to inhibit growth of normal as well as... -
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- Effective Delivery of Exogenous Compounds to the Optic Nerve by Intravitreal Injection of Liposome
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Lee J, Goh U, Park JH, Park SW, Heo H
- KMID: 2422072
- Korean J Ophthalmol.
- 2018 Oct;32(5):417-423.
- doi: 10.3341/kjo.2017.0128
PURPOSE: To improve the treatment efficiency of optic nerve diseases by delivering therapeutic materials to the optic nerve directly. METHODS: We tried to optimize liposomal composition to deliver a payload to... -
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- Concentration of Tobramycin in the Cornea and Sclera After Subconjunctival Injection of Negatively-charged Liposome Encapsulated Tobramycin in Rabbits
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Han SH, Kim EK, Kim HB, Kim HL
- KMID: 2122892
- J Korean Ophthalmol Soc.
- 1989 Feb;30(1):17-22.
Bacterial keratitis is a common ophthalmic disease. Recently, topical and subconjunctival therapy were equally effective in reducing the number of viable bacteria in experimental corneal ulcers. Subconjunctival injection produced high... -
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- The Concentration of Tobramycin in Cornea and Sclera After Subconjunctival Injection of Liposome-encapsulated Tobramycin in Rabbits
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Kim EK, Kim HB, Lee SC
- KMID: 2122861
- J Korean Ophthalmol Soc.
- 1988 Oct;29(5):809-813.
The authers investigated the effct of liposome encapsulation on the pharmacokinetics of tobramycin after subconjuctival in jnjection in rabbits. Tobramycin was encapsulated into neutral liposomes of phosphatidylcholine and cholesterol. The... -
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- Liposomes as Acitivators of Lipophilic Platinum (2 ) Complexes
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Han IS, Lee YJ
- KMID: 2175291
- J Korean Cancer Assoc.
- 1999 Feb;31(1):180-187.
PURPOSE: The goal of this study is to understand the activation processes that take place within the liposomal formulation of lipophilic diaminocyclohexane platinum (DACH-Pt) complexes, to identify the activated species... -
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- Development and Application of Cell-penetrating Peptides
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Yi H
- KMID: 2286271
- J Bacteriol Virol.
- 2013 Sep;43(3):177-185.
- doi: 10.4167/jbv.2013.43.3.177
Intracellular transduction of hydrophilic macromolecules has been problematic owing to the biochemical restriction imposed by lipid bilayer of the cytoplasmic membrane. Several technologies have been developed to improve the intracellular... -
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- Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy
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Park YM, Lee SJ, Kim YS, Lee MH, Cha GS, Jung ID, Kang TH, Han HD
- KMID: 1493611
- Immune Netw.
- 2013 Oct;13(5):177-183.
- doi: 10.4110/in.2013.13.5.177
Development of nano-sized carriers including nanoparticles, nanoemulsions or liposomes holds great potential for advanced delivery systems for cancer immunotherapy, as such nanostructures can be used to more effectively manipulate or... -
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- Macrophage Depletion by Clodronate Liposomes Suppresses Neointimal Formation After Carotid Artery Injury in Apolipoprotein E-Deficient Mice
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Hong SJ, Ahn TH, Shim WJ, Park SM, Choi JI, Park JS, Lim SY, Lim DS, Park CG, Seo HS
- KMID: 2225785
- Korean Circ J.
- 2008 May;38(5):244-249.
- doi: 10.4070/kcj.2008.38.5.244
BACKGROUND AND OBJECTIVES: Clodronate liposomes deplete phagocytic cells, thereby suppressing inflammation after vascular injury. We compared the effect of clodronate liposomes on macrophage depletion and neointimal formation in apolipoprotein E-deficient... -
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- Purification of Band 3 from the Human Erythrocyte Membrane and its Incorporation into Liposome
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Kim JR, Kim JH, Lee KY
- KMID: 2373862
- Yeungnam Univ J Med.
- 1986 Dec;3(1):41-48.
- doi: 10.12701/yujm.1986.3.1.41
Band 3, the predominant 95,000 dalton anion transport protein, is the major intrinsic glycoprotein of the human erythrocyte membrane. This anion carrier exists as a dimer and binds the cytoskeletons... -
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- The antibacterial effect of fatty acids on Helicobacter pylori infection
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Jung SW, Lee SW
- KMID: 2373769
- Korean J Intern Med.
- 2016 Jan;31(1):30-35.
- doi: 10.3904/kjim.2016.31.1.30
Eradication of Helicobacter pylori is recommended for the management of various gastric diseases, including peptic ulcers and mucosa-associated lymphoid tissue lymphoma. Because of the increasing prevalence of antibiotic resistance, the... -
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- Comparison of Antioxidant Activities of Some Flavonoids
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Jung HG, Jung MA, Song DU, Ahn BW, Yang SY
- KMID: 1807457
- Chonnam Med J.
- 2000 Jun;36(2):159-166.
This study was aimed to evaluate the relative antioxidant activities of some common flavonoids such as quercetin, rutin, catechin, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG). The antioxidant activities were... -
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- Development of Covalently Closed c-myb Antisense Oligonucleotides for Growth Inhibition of Leukemic Cells
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Moon IM, Park JG
- KMID: 2175232
- J Korean Cancer Assoc.
- 1999 Apr;31(2):348-359.
PURPOSE: Aberrant expression of the c-myb gene is often detected in transformed leukemic cells. Inhibition of c-myb expression by antisense oligos could be an effective way to abort rapid growth... -
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- The Effect of Subconjunctival Injection of Liposome Encapsulated Cytarabine on Proliferation of Fibroblasts
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Seong GJ, Hong YJ, Park SJ
- KMID: 1949975
- J Korean Ophthalmol Soc.
- 1992 Sep;33(9):885-891.
To know the effect of subconjunctival injection of liposome encapsulated cytarabine on proliferation of conjunctival fibroblasts, the conjunctiva was isolated at 180 degrees from the injection site 3 days after... -
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- Effective Inhibition of Cancer Cell Growth by a Novel Tripartite Transfection Complex Containing Ribbon Antisense Molecules to hTR
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Park JG
- KMID: 1804566
- Cancer Res Treat.
- 2004 Oct;36(5):308-314.
PURPOSE: In the present study, ribbon antisense to the hTR RNA, a component of the telomerase complex, was employed to inhibit telomerase activity and cancer cell growth. MATERIALS AND METHODS:... -
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- Effects of Chlorhexidine digluconate on Rotational Rate of n- (9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes
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Jang HO, Kim DW, Kim BI, Sim HG, Lee YH, Lee JH, Bae JH, Bae MK, Kwon TH, Yun I
- KMID: 1611230
- Korean J Physiol Pharmacol.
- 2004 Apr;8(2):83-88.
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids... -
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- The Synergistic Cell Killing Effects by the Transduction of the w-p53 Gene and 5-FU Administration in Colon Cancer Cell Lines
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Kim HJ, Lee SC, Lee IK, Kang WK, Oh ST, Chang SK
- KMID: 2096476
- J Korean Surg Soc.
- 2007 Dec;73(6):481-489.
PURPOSE: It is known that the wild-type p53 (w-p53) gene has several functions such as suppression of tumor cell growth, control of the cell cycle, stabilization of the genes and... -
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- Current Pharmacologic Approaches in Painful Bladder Research: An Update
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Andersson , Birder L
- KMID: 2400890
- Int Neurourol J.
- 2017 Dec;21(4):235-242.
- doi: 10.5213/inj.1735022.511
The symptoms of interstitial cystitis (IC)/bladder pain syndrome (BPS) may have multiple causes and involve many contributing factors. Traditional treatments (intravesical instillations) have had a primary focus on the bladder... -
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- Anticancer effect of liposome incorporated with methotrexate and antibody against tumor specific surface antigen of rat hepatoma
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Shin YS, Paik EM, Ahn YH, Kim BS, Kim YS
- KMID: 1097015
- Yonsei Med J.
- 1989 Sep;30(3):246-255.
- doi: 10.3349/ymj.1989.30.3.246
antibody against tumor specific surface membrane protein was produced by immunizing a New Zealand White rabbit with antigen (66 kDa) prepared from the plasma membrane of rat hepatoma induced... -
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- Effects of Nocodazole on Fine Structures in Co-cultured Vascular Endothelial Cells and Cancer Cell Lines
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Kim JY, Song IH, Lee JY, Sung EK, Lee Y
- KMID: 2040091
- Korean J Anat.
- 1999 Aug;32(4):459-474.
Endothelial cells were isolated from the aortic intima of Sprague-Dawley species, rat. These cells and each cancer cell line (HeLa, Hep G2, A549, L929 and NIH/3T3 cells) were co-cultivated in... -
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- Molecular Imaging of Biological Gene Delivery Vehicles for Targeted Cancer Therapy: Beyond Viral Vectors
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Min JJ, Nguyen VH, Gambhir SS
- KMID: 2051961
- Nucl Med Mol Imaging.
- 2010 Apr;44(1):15-24.
Cancer persists as one of the most devastating diseases in the world. Problems including metastasis and tumor resistance to chemotherapy and radiotherapy have seriously limited the therapeutic effects of present... -
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