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A case report of adult acute biphenotypic leukemia-hand mirror variant

Choi SJ, Seo EJ, Chi HS, Kim SH

  • KMID: 2225928
  • Korean J Clin Pathol.
  • 2000 Apr;20(2):137-141.
A case of acute biphenotypic leukemia with mixed blast morphology and combined myeloid and T-lymphoid features is reported. The leukemic cells consisted of small to medium sized hand mirror shaped...
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A case of biphenotypic acute leukemia with expression of the AML1-ETO gene rearrangement

Seo JH, Lee HW, Lim JE, Chung JW, Choi JR, Yang WI, Min YH

  • KMID: 2257629
  • Korean J Med.
  • 2009 May;76(5):617-621.
Biphenotypic acute leukemia (BAL) is a subtype of acute leukemia that expresses two different immunophenotypic lineages, most commonly myeloid and either B- or T-lymphoid lineages. This entity has been defined...
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A case of bullous pyoderma gangrenosum associated with refractory acute biphenotypic leukemia

Kang HJ, Lee JL, Lee KH, Hyun MS, Shin DH, Park JW, Cho HS

  • KMID: 1984900
  • Korean J Med.
  • 2004 Feb;66(2):200-203.
Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated acute leukemia. We report a case of pyoderma gangrenosum associated refractory acute biphenotypic leukemia wherein the malignant cells show a...
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Relapse of Biphenotypic Acute Leukemia as a Breast Mass

Shin HC

In acute leukemia, leukemic infiltration of the breast is extremely rare. We report a case of biphenotypic acute leukemia (BAL) that presented as a breast mass. A 30-year-old woman presented...
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Concomitant transformation of monoclonal gammopathy of undetermined significance to multiple myeloma and of essential thrombocythemia to acute biphenotypic leukemia 37 years after initial diagnosis

Niscola P, Catalano G, Fratoni S, Scaramucci L, de Fabritiis P, Caravita T

No abstract available.
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A Case of Transient Pancytopenia Preceding Childhood Acute Leukemia

Hur M, Lee DS, Cho HI, Shin S, Ahn HS, Shin HY

  • KMID: 2031023
  • Korean J Clin Pathol.
  • 1999 Oct;19(5):500-503.
Transient pancytopenia preceding acute lymphoblastic leukemia is an infrequent but well-known event, especially in childhood. We report a case of childhood acute leukemia preceded by transient pancytopenia and hepatitis. A...
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Biphenotypic Acute Leukemia with BCR-ABL mRNA Transcript b3a2 Type: A Case Report with Review of the Literature

Choi HW, Shin MG, Kim HJ, Lee IK, Yun JH, Kim HR, Kim YK, Yun HK, Cho D, Kee SJ, Shin JH, Suh SP, Ryang DW

Biphenotypic acute leukemia (BAL) is a subtype of leukemia of ambiguous lineage in the World Health Organization classification system. About one third of the cases have the Philadelphia chromosome, and...
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t(9;22) with 5'ABL1 Deletion and t(6;19) in Biphenotypic Acute Leukemia

Kim JE, Seo YH, Park PH, Kim KH, Song YH, Park SH, Seo EJ, Ahn JY

Biphenotypic acute leukemia (BAL) is a rare type of leukemia, comprises 4% of all acute leukemias. It is more common in adults and the clinical features, as related to marrow...
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Biphenotypic acute leukemia or acute leukemia of ambiguous lineage in childhood: clinical characteristics and outcome

Lee HG, Baek HJ, Kim HS, Park SM, Hwang TJ, Kook H

BACKGROUND: Acute leukemia (AL), not clearly assigned to myeloid, B-lymphoid, or T-lymphoid lineage, is classified as either biphenotypic acute leukemia (BAL) based on the European Group for Immunological Classification of...
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Tuberculous Lymphadenitis in Patients with Myelogenous Leukemia

Lee CS, Song JS, Choe PG, Cho JH, Bang JW, Park KH, Park WB, Kim HB, Kim NJ, Yoon SS, Park S, Kim BK, Oh MD, Choe KW

  • KMID: 2054318
  • Infect Chemother.
  • 2006 Oct;38(5):266-270.
During the neutropenic phase, leukemia patients receiving chemotherapy are prone to bacterial and, fungal infections; occasionally mycobacterial, viral and protozoal organisms may also cause infections. Mycobacterium tuberculosis infection was reported...
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Expression of Granulocyte Colony-Stimulating Factor Receptor (G-CSFR) and Clinical Correlates in Acute Leukemia

Yoon SY, Bae SY, Seo JH, Kim BS, Kim YK, Lee KN, Rheem I

  • KMID: 1515015
  • Korean J Hematol.
  • 2003 Nov;38(4):246-252.
BACKGROUND: Granulocyte colony-stimulating factor (G-CSF) is commonly used to reduce leukopenic period during treatment of malignancy including acute leukemia. Leukemic blasts expressing granulocyte colony-stimulating factor receptor (G-CSFR) were reported and...
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Clinical Characteristics of Biphenotypic Acute Leukemia in Childhood: A Single Institutional Experience

Lee MJ, Seo JJ, Park CJ, Chi HS, Moon HN, Ghim TT

  • KMID: 2278264
  • Korean J Pediatr Hematol Oncol.
  • 2003 Apr;10(1):49-57.
PURPOSE: The diagnostic criteria of the biphenotypic acute leukemia (BAL) are based on the number and degree of the specificity of the immunological markers expressed on the leukemic blasts. The...
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Analysis of Discrepancies Between G-banding and FISH in Hematologic Abnormalities

Lee DY, See CJ, Hwang CD, Cho HI, Lee DS

  • KMID: 2089678
  • Korean J Clin Pathol.
  • 2001 Dec;21(6):445-450.
BACKGROUND: The effective treatment of hematologic malignancies depends upon application of different therapeutic strategies by selecting patients known as the high risk group and the detection of malignant cells that...
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Generation and Qualification of Functionally Active Leukemia-derived DCs from Malignant Blasts in Acute Leukemia

Baek S, Jung CW, Kim MJ, Kim K, Ahn JS, Lee H

BACKGROUND: Dendritic cells (DCs) are increasingly being utilized for anti-cancer immunotherapy. Acute myeloid leukemia (AML) blasts are able to generate leukemia-derived DC. Advances in culture techniques and AML-DC characterization justify...
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Growth Patterns in Patients with Acute Leukemia after Allogeneic Stem Cell Transplantation

Chueh HW, Lee SH, Yoo KH, Sung KW, Koo HH

  • KMID: 2168929
  • Clin Pediatr Hematol Oncol.
  • 2011 Apr;18(1):19-26.
BACKGROUND: Growth of the children who received allogeneic stem cell transplantation (allo-SCT) is known to be impaired. We analyzed the patterns of growth in long-term survivors of acute leukemia who...
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Mixed-phenotype acute leukemia treated with decitabine

Lee JY, Lee SM, Lee JY, Kim KH, Choi MY, Lee WS

No abstract available.
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Clinical Significance of Co-expression of Aberrant Antigens in Acute Leukemia

Jeong SH, Lee HW, Kang SY, Ahn MS, Hwang YH, Choi JH, Kim HC, Cho SR, Park JS

BACKGROUND: Acute leukemias co-expressing myeloid and lymphoid antigens but does not meet the criteria for biphenotypic acute leukemia (BAL) is common, however its clinical significance is not fully defined. METHODS: In...
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Hematological Significance of Southern Blot Test for bcr-abl Rearrangement and the Breakpoints within Major bcr in Chronic Myelogenous Leukemia

Park SS, Lee YK, Cho SI, Cho HI

  • KMID: 1907541
  • J Clin Pathol Qual Control.
  • 1997 Dec;19(2):261-271.
BACKGROUND: Bcr-abl rearrangement is the molecular hallmark of chronic myelogenous leukemia, of which analysis is the standard test for the diagnosis of chronic myelogenous leukemia (CML). Southern blot analysis is...
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Cytogenetically Unrelated Clones in Hematologic Malignancies

Cho S, Huh J, Seong C, Chung W

  • KMID: 2305442
  • Korean J Lab Med.
  • 2004 Jun;24(3):189-193.
BACKGROUND: The origin of hematologic malignancies has been known to be monoclonal. In most cases, the same or obviously related chromosomal abnormliaties are found and cytogenetically unrelated clones are uncommon....
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Relationship between In Vitro Chemosensitivity assessed with MTT Assay and Clinical Outcomes in 103 Patients with Acute Leukemia

Jun KR, Jang S, Chi HS, Lee KH, Lee JH, Choi SJ, Seo JJ, Moon HN, Im HJ, Park CJ

BACKGROUND: Cellular drug resistance is supposed to play a major role in chemotherapy failure or relapse. The purpose of this study was to analyze the relationship between in vitro...
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