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Initial Response of the Korean Society for Laboratory Medicine to the COVID-19 Pandemic

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JAK2V617F-Positive Acute Myeloid Leukemia: Clinicopathological Features of Two Cases

Lee Y, Lee JY, Lee JO, Bang SM, Hwang SM

Although the JAK2V617F mutation is a common genetic basis for the BCR-ABL1-negative myeloproliferative neoplasm (MPN), it is very rarely observed in acute myeloid leukemia (AML) without antecedent MPN. While JAK2V617F...
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Secondary Germline CDKN2A Mutation Identified using Liquid Biopsy in a Patient with Esophageal Cancer

Jang H, Won D, Shin S, Park SY, Kim DJ, Lee ST, Choi JR

Liquid biopsy is a non-invasive method for tumor genotyping through detecting the circulating tumor DNA (ctDNA). Here, we describe the case of an esophageal squamous cell cancer patient in which...
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Development of Cryopreserved Red Blood Cell Panels as Biological Reference Standards for Performance Evaluation of ABO and D Blood Grouping Reagents

Cho YK, Kim S, Lim J, Ko DH, Choi SJ, Kim HO

Background: Accurate blood typing is essential for blood transfusions, and requires the constant evaluation and maintenance of ABO and D blood grouping reagents. In the present study, we developed cryopreserved...
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A Case of Catheter-Related Bloodstream Infection Caused by Tsukamurella tyrosinosolvens

Kim S, Kim TS, Park H, Park JH

The genus Tsukamurella is an aerobic actinomycete found in soil, and rarely infects humans. Herein, we report a case of catheter-related bloodstream infection caused by T. tyrosinosolvens. An 8-year-old girl...
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Age-Specific Reference Values of Anti-Müllerian Hormone in Korean Women with Normal Menstruation: Time Trend and Clinical Suitability (2015–2021)

Kim HJ, Park JY, Han MS

Anti-Müllerian hormone (AMH) levels can be affected by various factors, including age, lifestyle, and test method. This study aimed to review the time trend of AMH levels and the clinical...
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Identification of a de novo ANK1 Variant in a Patient with Hereditary Spherocytosis on Multi-gene Panel Testing

Yoon SJ, Cho EH, Woo HY, Park H, Jung HL, Kwon MJ

Hereditary spherocytosis (HS) is caused by defects in red blood cell membrane components encoded by SPTA1, SPTB, ANK1, SLC4A1, and EPB42. The low sensitivity and specificity of conventional tests such...
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Analytical and Clinical Assessment of Prostate Specific Antigen Using an HISCL-5000 Chemiluminescence Immunoassay

Han J, Jekarl DW, Lee S, Kim M, Kim Y

Background: Prostate cancer (PCa) is the leading cause of cancer-related death worldwide. Prostate specific antigen (PSA) is a useful biomarker that can be screened for the diagnosis and prognosis of...
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A Case of Bacteremia Caused by Pantoea ananatis in a Patient Receiving Home Parenteral Nutrition

Lee J, Park JH, Kim TS, Park H

Pantoea ananatis is a Gram-negative, rod-shaped, non-spore-forming, motile bacterium that belongs to the family Erwiniaceae of the order Enterobacterales. In this study, we report the first Korean case of bacteremia...
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Comparison of Automated and Manual Gating of Lymphocyte Subsets in Hematopoietic Stem Cell Transplantation Recipients

Lee H, Kim J, Lee J, Jung J, Oh EJ

Background: Lymphocyte subset analysis is essential to evaluate the engraftment status in hematopoietic stem cell transplantation (HSCT). Automated gating tools are widely used for flow cytometry analysis. Unlike healthy individuals,...
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Validation of Hematology Rapid Reporting System for Complete Blood Cell Count with Differential

Lee J, Yoon SY, Park JY, Kim J

Background: Complete blood cell count (CBC) test, peripheral blood smears (PBS), and automatic hematology analyzers are used to screen patients with high-risk hematology malignancies. In this study, the workflow of...
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Evaluation of Copeptin for Diagnosing Non-ST Segment Elevation Acute Myocardial Infarction in Patients with Chest pain and Mild Troponin I Elevation

Kim J, Kim J, Lim J, Kim SY, Kwon GC, Koo SH

Background: Although troponin assays improve the detection of acute myocardial infarction (AMI), troponin elevation is observed in various non-ischemic conditions. Studies have proposed that, when used in combination with a...
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Identification of Candida auris and Closely Related Species Using a New Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, the ASTA MicroIDSys System

Ma T, In YH, Byun SA, Lee GY, Choi MJ, Lee SY, Won EJ, Choi HJ, Choi HW, Kee SJ, Kim SH, Shin MG, Shin JH

Candida auris is a multidrug-resistant fungal pathogen emerging worldwide that is closely related to the C. haemulonii species complex. The ASTA MicroIDSys (ASTA, Korea) is a new matrix-assisted laser desorption/ionization...
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