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A case study assessing the impact of mating frequency on the reproductive performance of the Hawaiian bobtail squid Euprymna scolopes

Cecere A, Cook R, Miyashiro T

Background The symbiosis between the Hawaiian bobtail squid Euprymna scolopes and bacterium Vibrio fischeri serves as a model for investigating the molecular mechanisms that promote the initial formation of animal-bacterial symbioses. Research with this system frequently depends on freshly hatched E. scolopes,...
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Staphylococcus xylosus and Staphylococcus aureus as commensals and pathogens on murine skin

Battaglia M, Garrett‑Sinha L

Skin ulcers, skin dermatitis and skin infections are common phenomena in colonies of laboratory mice and are often found at increased prevalence in certain immunocompromised strains. While in many cases these skin conditions are mild, in other cases...
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The mesocortical dopaminergic system cannot explain hyperactivity in an animal model of attention deficit hyperactivity disorder (ADHD)‑ Spontaneously hypertensive rats (SHR)

Aydin A, Adiguzel E

Background Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neuropsychiatric disorders with morphological brain abnormalities. There is a growing body of evidence that abnormalities in the dopaminergic system may account for ADHD pathogenesis. However, it is not clear whether the dopaminergic system...
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TRPC expression in human periodontal ligament cells and the periodontal tissue of periodontitis mice: a preliminary study

Kim A, Kim A, Jeon Y, Yoo Y, Yang Y, Bak E

Background Transient receptor potential canonical (TRPC) channels are non-selective cationic channels with perme‑ ability to ­Ca2+ and ­Na+ . Despite their importance, there are currently few studies on TRPC in the periodontal ligament (PDL) and bone cells...
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Ameliorative effect of hesperidin against high dose sildenafil‑induced liver and testicular oxidative stress and altered gene expression in male rats

Laila I, Kassem S, Mohamed Diab M

Background The clinical use of sildenafil citrate (Viagra), a drug used to treat erectile dysfunction, is limited because of its many side effects on tissues. In this context, we aimed to investigate the protective effects of hesperidin, a citrus flavonoid, on hepatic...
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Exploration of the anti‑diabetic potential of hydro‑ethanolic leaf extract of Koenigia polystachya L.: an edible wild plant from Northeastern India

Kiba A, Saha D, Das B

Background Globally, medicinal plants are used to treat diseases like diabetes. The present study evaluates the possible antioxidant, acute oral toxicity, the in-vitro and in-vivo antidiabetic potential of the hydro-ethanolic leaf extract of Koenigia polystachya (HELeKP) against beta-cell damage...
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