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Spot Hydrogen Breath Test: A Great Hockey Player Plays Where the Puck Is Going to Be

Lee TH

  • KMID: 2546963
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):407-408.
  • doi: 10.5056/jnm23136
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Deciphering the Immune Complexity of Esophageal Achalasia

Chung H

  • KMID: 2546962
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):405-406.
  • doi: 10.5056/jnm23141
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Multiple Sclerosis Is Associated With Achalasia and Diffuse Esophageal Spasm

Kim Y, Shibli F, Fu Y, Song G, Fass R

  • KMID: 2546972
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):478-485.
  • doi: 10.5056/jnm22173
Background/Aims Multiple sclerosis (MS) is an inflammatory disease characterized by the demyelination of primarily the central nervous system. Diffuse esophageal spasm (DES) and achalasia are disorders of esophageal peristalsis and esophagogastric...
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Constipation in Patients With Chronic Kidney Disease

Cha RR, Park SY, Camilleri M, the Constipation Research Group of Korean Society of Neurogastroenterology and Motility

  • KMID: 2546966
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):428-435.
  • doi: 10.5056/jnm23133
Constipation is a frequent symptom in patients with chronic kidney disease (CKD). This review outlines the mechanisms and management of constipation in patients with CKD from a physician’s perspective. Common...
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Spot Hydrogen Breath Test for Predicting Response to Low Fermentable Oligo-, Di-, Mono-saccharides, and Polyols Dietary Advice in Patients With Bloating

Somvanapanich P, Pitisuttithum P, Sirimongkolkasem J, Rattanachaisit P, Jangsirikul S, Patcharatrakul T, Gonlachanvit S

  • KMID: 2546975
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):513-519.
  • doi: 10.5056/jnm22214
Background/Aims An increase in postprandial intestinal gas plays a role in bloating symptoms. We aim to study the utility of spot breath hydrogen (H 2 ) level in predicting the response...
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The Effect of Curcumin on the Gut-Brain Axis: Therapeutic Implications

Enayati A, Soghi A, Butler AE, Rizzo M, Sahebkar A

  • KMID: 2546964
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):409-418.
  • doi: 10.5056/jnm23065
The gut-brain axis describes the bidirectional communication between the gut, the enteric nervous system, and the central nervous system. The gut-brain axis has attracted increasing attention owing to its regulatory...
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Modern Achalasia: Diagnosis, Classification, and Treatment

Pesce M, Pagliaro M, Sarnelli G, Sweis R

  • KMID: 2546965
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):419-427.
  • doi: 10.5056/jnm23125
Achalasia is a major esophageal motor disorder featured by the altered relaxation of the esophagogastric junction in the absence of effective peristaltic activity. As a consequence of the esophageal outflow...
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Revisiting the Role of Esophageal Mucosal Dilated Intercellular Spaces in the Diagnosis and Pathophysiology of Heartburn

Gorgulu V, Ergun P, Kipcak S, Doganavsargil B, Sifrim D, Bor S

  • KMID: 2546967
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):436-445.
  • doi: 10.5056/jnm22142
Background/Aims Dilated intercellular spaces (DISs) facilitate the diffusion of noxious agents into the deep layers of the esophageal epithelium. The role of DIS in heartburn pathogenesis is still controversial. Therefore, we...
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Non-cardiac Chest Pain in Japan: Prevalence, Impact, and Consultation Behavior - A Population-based Study

Chen J, Oshima T, Kondo T, Tomita T, Fukui H, Shinzaki S, Miwa H

  • KMID: 2546968
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):446-454.
  • doi: 10.5056/jnm22184
Background/Aims Non-cardiac chest pain (NCCP) is defined as recurring angina-like retrosternal chest pain of non-cardiac origin. Information about the epidemiology of NCCP in Japan is lacking. We aim to determine the...
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Achalasia and Hiatal Hernia: A Rare Association and a Therapeutic Challenge

Tutuian G, Leandri C, Tutuian R, Scialom S, Leconte M, Dohan A, Coriat R, Chaussade S, Barret M

  • KMID: 2546969
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):455-459.
  • doi: 10.5056/jnm22151
Background/Aims Achalasia and hiatal hernia are rarely associated. The aim of the current study is to explore the clinical and manometric findings in patients with achalasia and hiatal hernia, and to...
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Distinct Effects of Non-absorbed Agents Rifaximin and Berberine on the Microbiota-Gut-Brain Axis in Dysbiosis-induced Visceral Hypersensitivity in Rats

Zhang J, Zhang C, Zhang T, Zhang L, Duan L

  • KMID: 2546976
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):520-531.
  • doi: 10.5056/jnm22182
Background/Aims Irritable bowel syndrome (IBS) is accepted as a disorder of gut-brain interactions. Berberine and rifaximin are non-absorbed antibiotics and have been confirmed effective for IBS treatment, but there is still...
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Imbalance of Innate and Adaptive Immunity in Esophageal Achalasia

Yao L, Liu Z, Chen W, Xu J, Xu X, Xu J, Ma L, Li X, Li Q, Zhou P

  • KMID: 2546973
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):486-500.
  • doi: 10.5056/jnm21246
Background/Aims Previous studies reveal that immune-mediated neuroinflammation plays a key role in the etiology of esophageal achalasia. However, the understanding of leucocyte phenotype and proportion is limited. This study aim to...
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A Higher Manometric Esophageal Length to Height Ratio in Achalasia Explains the Lower Prevalence of Hiatal Hernia

Coss-Adame E, Furuzawa-Carballeda J, Perez-Ortiz AC, López-Ruiz A, Valdovinos MA, Sánchez-Gómez J, Peralta-Figueroa J, Olvera-Prado H, López-Verdugo F, Narváez-Chávez S, Santés-Jasso , Aguilar-León D, Torres-Villalobos G

  • KMID: 2546974
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):501-512.
  • doi: 10.5056/jnm22139
Background/Aims The evidence suggests that a shorter esophageal length (EL) in gastroesophageal reflux disease (GERD) patients is associated with the presence of hiatal hernia (HH). However, there are no reports of...
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Real-world Prescription Patterns and Patient Satisfaction Regarding Maintenance Therapy of Gastroesophageal Reflux Disease: An Observational, Cross-sectional, Multicenter Study

Huh CW, Son NH, Youn YH, Jung DH, Kim MK, Gong EJ, Huh KC, Kim SY, Park MI, Lee JY, Kwon JG, Kim JH, Shin CM, Jung KW, Hong SJ, Kim HM, Choi SC, Jung HK, Kim HJ, Lee KJ

  • KMID: 2546971
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):470-477.
  • doi: 10.5056/jnm23088
Background/Aims Gastroesophageal reflux disease (GERD) is a common chronic gastrointestinal disorder that typically requires long-term maintenance therapy. However, little is known about patient preferences and satisfaction and real-world prescription patterns regarding...
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On-demand Versus Continuous Maintenance Treatment With a Proton Pump Inhibitor for Mild Gastroesophageal Reflux Disease: A Prospective Randomized Multicenter Study

Jung DH, Youn YH, Jung HK, Kim SY, Huh CW, Shin CM, Oh JH, Huh KC, Park MI, Choi SC, Kim KB, Park SY, Kwon JG, Cho YK, Park JH, Shin JE, Gong EJ, Kim JH, Hong SJ, Kim HJ, Jee SR, Lee JY, Jung KW, Kim HM, Lee KJ

  • KMID: 2546970
  • J Neurogastroenterol Motil.
  • 2023 Oct;29(4):460-469.
  • doi: 10.5056/jnm23130
Background/Aims It remains unclear which maintenance treatment modality is most appropriate for mild gastroesophageal reflux disease (GERD). We aimed to compare on-demand treatment with continuous treatment using a proton pump inhibitor (PPI)...
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