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The Efficacy and Safety of Leflunomide in the Treatment of Rheumatoid Arthritis

Choe JY

No abstract available.
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Drug Hypersensitivity Syndrome Induced by Leflunomide

Kim HW, Park HC, Kim JE, Ko JY, Ro YS

  • KMID: 2247252
  • Korean J Dermatol.
  • 2013 Mar;51(3):226-227.
No abstract available.
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Cryptococcal Tenosynovitis of the Hand in a Patient with Rheumatiod Arthritis: A Case Report

Kim JH, Shin DJ, Byun YS, Kim SW, Kim TE

  • KMID: 2323442
  • J Korean Soc Surg Hand.
  • 2011 Dec;16(4):251-254.
Cryptococcosis is a fungal infection caused by Cryptococcus neoformans which is frequently occurred in the immunosuppressed host. Any organ or tissue may become infected, however, tendon sheath infection is extremely...
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Valproate-induced Hyperammonemic Encephalopathy: A Case Report

Yoo JY, Yang HS

Valproate is widely used because of broad spectrum of action, but it can produce an encephalopathy resulting from hyperammonemia even at the therapeutic range of valproate and is called as...
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A Case of Epilepsy Exhibiting a Severe, Dose-Dependent, Memory Deficit after Zonisamide Administration

Lee JM, Seo JG, Kim SY, Hwang YH, Lee HW, Suh CK, Kwon SH, Park SP

  • KMID: 2181933
  • J Korean Epilepsy Soc.
  • 2008 Jun;12(1):52-54.
Zonisamide (ZNS) has been proven as a safe, effective, and well-tolerated antiepileptic drug. We report an epilepsy patient who had a severe, dose-dependent, memory deficit after ZNS administration. A 65-year-old...
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A Case of Combining Intravenous Immunoglobulin and Leflunomide for BK Nephropathy

Cho SY, Bae JM, Nam WJ, Kim JG, Kim SH, Oh DJ, Yu SH

  • KMID: 2263746
  • Korean J Med.
  • 2011 Oct;81(4):512-516.
BK virus nephropathy has emerged as an important cause of renal allograft dysfunction. It affects 1-10% of renal transplant patients and results in significant graft dysfunction in more than 50%...
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A Case of Pneumocystis Jirovecii Pneumonia in a Patient with Rheumatoid Arthritis

Choi EY, Kim JO, Kim YS, Yoon HJ, Jun JB, Sung YK

We report a 67-year-old woman who developed Pneumocystis jirovecii pneumonia (PJP) as a complication of treatment with immunosuppressant, such as methotrexate and leflunomide, for rheumatoid arthritis. She had mild fever...
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Streptococcus salivarius pneumonia with pulmonary nocardiosis in a rheumatoid arthritis patient treated with immunosuppressants

Jeong I, Heo EY, Lee JS, Kim HR, Lee EY, Kim YW, Yang SC

  • KMID: 2305815
  • Korean J Med.
  • 2009 Jul;77(1):128-132.
Streptococcus salivarius is a Gram-positive organism that belongs to the viridians group of streptococci. It is a relatively non-virulent bacterium that is part of the normal flora. It is rarely...
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New drugs for Rheumatoid arthritis

Seo YI

  • KMID: 2257380
  • Korean J Med.
  • 2009 Jan;76(1):12-17.
Since the late 1990s, based on scientific advancement and biotechnological improvement, many effective drugs such as leflunomide and biologic agents for rheumatoid arthritis (RA) have been developed. These include TNF-alpha...
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Primary Cryptococcal Tenosynovitis in a Patient with Rheumatoid Arthritis

Seo AY, Han SW, Kwon KT, Kwak EK, Lee MJ, Kang SH

Here, we report a case of primary cryptococcal tenosynovitis and arthritis caused by worsened cellulitis in a patient with rheumatoid arthritis (RA) who had been taking methotrexate and leflunomide. The...
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Leflunomide Treatment in BK Virus Associated Nephropathy after Renal Transplantation

Son YK, Oh JS, Oh HJ, Shin YH, Kim JK, Jeong HJ

  • KMID: 1465941
  • Korean J Nephrol.
  • 2009 May;28(3):211-218.
PURPOSE:BK virus associated nephropathy (BKVAN) affects 1-10% of kidney transplant (KT) patients and it produces a progressive destruction of allograft. Reducing immunosuppression is the only way to save the graft,...
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Zonisamide Changes Unilateral Cortical Excitability in Focal Epilepsy Patients

Joo EY, Kim HJ, Lim YH, Ji KH, Hong SB

BACKGROUND AND PURPOSE: To evaluate changes in cortical excitability induced by zonisamide (ZNS) in focal epilepsy patients. METHODS: Twenty-four drug-nasmall yi, Ukrainianve focal epilepsy patients (15 males; overall mean age 29.8...
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A Case of Interstitial Pneumonitis in a Patient with Rheumatoid Arthritis Treated with Leflunomide

Shin AY, Kim SS, Kim KH, Ju IN, Ko HJ

  • KMID: 2319182
  • Tuberc Respir Dis.
  • 2009 Jun;66(6):477-481.
Leflunomide, a disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis has been available in Korea since 2003. Leflunomide-associated interstitial pneumonitis has been appearing recently. A 25-year-old woman with...
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Ganciclovir and Leflunomide Combination Therapy for a Patient with Cytomegalovirus Pneumonia after Unrelated Allogenic Stem Cell Transplantation

Lim JH, Lee YN, Ryu YS, Kim HJ, Kim KH, Kim SH, Kim HJ, Lee SC, Bae SB, Kim CK, Lee KT, Park SK, Won JH, Hong DS, Park HS, Park JS, Lee YK

Cytomegalovirus (CMV) infection is an important cause of morbidity and mortality among transplant recipients. The first line standard therapy for CMV pneumonia is treatment with a combination of ganciclovir and...
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Pharmacotherapy for obesity

Kim KK

Due to its serious comorbidities and high prevalence, obesity is one of the heaviest burdens for public health. Although diet, exercise and behavioral modification are the first-line treatment for obesity,...
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New antiepileptic drugs. II. Clinical use

Lee BI

No abstract available.
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Polyomavirus Disease in Kidney Transplantation

Hwang YH, Ahn C, Kwon OJ, Kim SI, Kim YL, Choi YJ

  • KMID: 2201912
  • J Korean Soc Transplant.
  • 2008 Jun;22(1):13-20.
Polyomavirus disease is a re-emerging infectious complication in renal transplantation. It manifests as symptomless renal dysfunction and progresses to graft loss unless the prompt diagnosis and intervention are initiated. A...
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Hepatotoxicity of Combination Treatment with Leflunomide and Methotrexate in RA Patients

Chang JH, Jung ES, Lee JH, Yoon BY, Lee CH, Lee YW

OBJECTIVE: Leflunomide is the newest disease-modifying anti-rheumatic drug (DMARD) that is known to have an equivalent clinical efficacy and tolerability to methotrexate (MTX). Previous studies reported that a co-treatment with...
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Changes in the Metabolic Parameters and Positive and Negative Syndrome Scale (PANSS) Scores of Patients with Schizophrenia 8 Weeks after Switching to Paliperidone

Jeong TY, Choi YM, Kim B, Lee DW, Gim MS, Park JH

  • KMID: 2250298
  • Korean J Biol Psychiatry.
  • 2012 May;19(2):84-90.
OBJECTIVES: The purpose of this study was to examine the changes in metabolic parameters and Positive and Negative Syndrome Scale (PANSS) scores of patients previously treated with atypical antipsychotic drugs...
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The target concentration of remifentanil to suppress the hemodynamic response to endotracheal intubation during inhalational induction with desflurane

Lee J, Jung CW

BACKGROUND: Anesthesia induction with desflurane is troublesome because of the frequent sympathetic hyperactivity during desflurane administration. We thought that a low concentration of desflurane combined with a target-controlled infusion (TCI)...
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