- Molecular perspective of iron uptake, related diseases, and treatments
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Shokrgozar N, Golafshan
- KMID: 2451050
- Blood Res.
- 2019 Mar;54(1):10-16.
- doi: 10.5045/br.2019.54.1.10
Iron deficiency anemia and anemia of chronic disorders are the most common types of anemia. Disorders of iron metabolism lead to different clinical scenarios such as iron deficiency anemia, iron... -
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- Six Cases of Iron Containing Plasma Cells
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Nah J, Chi HS
- KMID: 2039315
- Korean J Clin Pathol.
- 1997 Feb;17(1):28-33.
Iron in plasma cells has been described in patients with diseases characterized by iron overload. We observed iron-containing plasma cells in the bone marrow aspirates of 6 patients with anemia.... -
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- Regulation of Iron and Its Significance in Obesity and Complications
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Chan YK, Sung HK, Sweeney G
- KMID: 2271135
- Korean J Obes.
- 2014 Dec;23(4):222-230.
- doi: 10.7570/kjo.2014.23.4.222
Iron is an essential micronutrient with important roles in many critical physiological processes, especially as a structural component of hemoglobin responsible for oxygen transport. Iron homeostasis is tightly regulated, yet... -
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- Efficacy and safety of combined oral iron chelation therapy with deferasirox and deferiprone in a patient with beta-thalassemia major and persistent iron overload
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Alavi S, Sadeghi E, Ashenagar
- KMID: 2172829
- Blood Res.
- 2014 Mar;49(1):72-73.
- doi: 10.5045/br.2014.49.1.72
No abstract available. -
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- Associations between Lifestyle Factors and Iron Overload in Korean Adults
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Kim H, Shin C, Baik I
- KMID: 2355299
- Clin Nutr Res.
- 2016 Oct;5(4):270-278.
- doi: 10.7762/cnr.2016.5.4.270
It has been suggested that iron overload, which indicates the accumulation of iron, generates cellular reactive oxygens and causes peroxide damages to the body. Such oxidative stresses, in a broader... -
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- The Prevalence of Peripheral Iron Overload and the Presence of HFE gene (H63D) Mutation among the Korean Patients with Nonalcoholic Fatty Liver Disease
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Lee D, Jeong SH, Lee M, Cho YA, Kim JW, Park Y, Hwang JH, Kim NY, Lee DH
- KMID: 760721
- Korean J Hepatol.
- 2007 Jun;13(2):174-184.
BACKGROUNDS/AIMS: There are controversies on the role of iron overload in the mechanism of liver injury in nonalcoholic fatty liver disease (NAFLD). The aim of this study was to... -
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- Causes of Hyperferritinemia and Red Blood Cell Transfusion
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Kim MS, Kim SH
- KMID: 2435621
- Korean J Blood Transfus.
- 2018 Dec;29(3):273-281.
- doi: 10.17945/kjbt.2018.29.3.273
BACKGROUND: Ferritin is used to detect iron overload in patients with chronic red blood cell transfusions. Although ferritin reflects the amount of iron storage in the body, it may increase... -
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- Transfusional Iron Overload and Choroid Plexus Hemosiderosis in a Pediatric Patient: Brain Magnetic Resonance Imaging Findings
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Kim MS, Lee HY, Lim MK, Kang YH, Kim JH, Lee KH
- KMID: 2468058
- Investig Magn Reson Imaging.
- 2019 Dec;23(4):390-394.
- doi: 10.13104/imri.2019.23.4.390
Hemosiderosis is characterized by the deposition of excess iron in body tissues. The choroid plexus is an important part of the central nervous system that can be the primary site... -
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- Role of hepcidin in the pathophysiology and diagnosis of anemia
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D'Angelo G
- KMID: 2270720
- Blood Res.
- 2013 Mar;48(1):10-15.
- doi: 10.5045/br.2013.48.1.10
This review summarizes the central role of hepcidin in the iron homeostasis mechanism, the molecular mechanism that can alter hepcidin expression, the relationship between hepcidin and erythropoiesis, and the pathogenetic... -
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- Effects of Iron Overload during Pregnancy on Oxidative Stress in Maternal Rats
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Park MN, Lee YS
- KMID: 2268340
- Korean J Nutr.
- 2011 Feb;44(1):5-15.
- doi: 10.4163/kjn.2011.44.1.5
Although iron is an essential mineral, excess iron intake during pregnancy may increase oxidative stress in tissues. This study was conducted to investigate the effects of iron overload during pregnancy... -
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- Effect of Iron-Chelator Deferiprone on the In Vitro Growth of Staphylococci
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Kim CM, Shin SH
- KMID: 1779132
- J Korean Med Sci.
- 2009 Apr;24(2):289-295.
- doi: 10.3346/jkms.2009.24.2.289
The standard iron-chelator deferoxamine is known to prevent the growth of coagulase-negative staphylococci (CoNS) which are major pathogens in iron-overloaded patients. However, we found that deferoxamine rather promotes the growth... -
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- Clinical evaluation of hemochromatosis with end-stage renal disease
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Choi BD, Joo HW, Kang KP, Park MS, Kim MG, Kim SH, Park WD
- KMID: 1522649
- Korean J Med.
- 2007 Feb;72(2):237-241.
Hemochromatosis is almost always a consequence of treatment for anemia in long term hemodialysis patients who have undergone frequent blood transfusions and iron therapy. Clinically, iron overload may be a... -
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- Korean Guideline for Iron Chelation Therapy in Transfusion-Induced Iron Overload
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Jang JH, Lee JH, Yoon SS, Jo DY, Kim HJ, Chung J, Lee JW
- KMID: 1777651
- J Korean Med Sci.
- 2013 Nov;28(11):1563-1572.
- doi: 10.3346/jkms.2013.28.11.1563
Many Korean patients with transfusion-induced iron overload experience serious clinical sequelae, including organ damage, and require lifelong chelation therapy. However, due to a lack of compliance and/or unavailability of an... -
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- MR Imaging Findings of the Pituitary Gland in Patients with Transfusional Hemochromatosis: Two Case Reports
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Yoon CD, Song CJ, Shin BS, Oh KJ, Cho DY
- KMID: 1834431
- J Korean Radiol Soc.
- 2007 Jun;56(6):523-525.
- doi: 10.3348/jkrs.2007.56.6.523
Hemochromatosis is a disorder caused by excessive iron deposition in parenchymal cells that leads to cellular damage and organ dysfunction. The excessive iron overload of secondary hemochromatosis is associated with... -
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- Endocrinopathy in Hemochromatosis Patients Multi-Transfused for Aplastic Anemia
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Kwon HJ, Joo SW, Kook JH, Rha JY, Kook H, Woo YJ, Hwang TJ
- KMID: 2072492
- Korean J Pediatr Hematol Oncol.
- 2001 Oct;8(2):181-188.
PURPOSE: Chronic blood transfusions result in excessive iron deposition leading to eventual tissue damage and impaired function of organs, such as the liver, spleen, pancreas, skin, thyroid, and heart.... -
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- A Case of Hemochromatosis
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Oh JE, Lim JY, Kim SY, Choi YW, Myung KB, Seong YA, Choi HY
- KMID: 2248109
- Korean J Dermatol.
- 2008 Jul;46(7):937-940.
Hemochromatosis is a disorder of iron metabolism leading to irreversible damage to various organs due to progressive tissue iron overload. It is characterized by liver cirrhosis, heart failure, diabetes and... -
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- Deferiprone Related Arthropathy in 11-Year-Old Boy with Hereditary Spherocytosis
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Seo YK, Han JK, Suh WS, Park KB
- KMID: 2470422
- Soonchunhyang Med Sci.
- 2019 Dec;25(2):155-158.
- doi: 10.0000/sms.2019.25.2.155
Regular transfusion therapy in children with intractable hematologic disorder results in hemosiderosis. It causes several organ damages such as liver, heart, and endocrine system and increases risk of infection. Thus,... -
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- Hemoglobin Andrew-Minneapolis: Hemolytic Erythrocytosis and Severe Iron Overload in Toxic Liver Cirrhosis
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Zur B, Stoffel-Wagner B, Ludwig M
- KMID: 2434490
- Ann Lab Med.
- 2012 Nov;32(6):450-451.
No abstract available. -
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- Efficacy and safety of deferiprone (Ferriprox), an oral iron-chelating agent, in pediatric patients
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Won SC, Han DK, Seo JJ, Chung NG, Park SK, Park KB, Kook H, Lyu CJ
- KMID: 2252088
- Korean J Hematol.
- 2010 Mar;45(1):58-61.
- doi: 10.5045/kjh.2010.45.1.58
BACKGROUND: Iron overload is a predictable and life-threatening complication in patients dependent on the regular transfusion of RBCs. The aims of this study were to investigate the efficacy and safety... -
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- Relationship between liver iron concentration determined by R2-MRI, serum ferritin, and liver enzymes in patients with thalassemia intermedia
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Al-Momen H, Jasim SK, Hassan QA, Ali HH
- KMID: 2429306
- Blood Res.
- 2018 Dec;53(4):314-319.
- doi: 10.5045/br.2018.53.4.314
BACKGROUND: Iron overload is a risk factor affecting all patients with thalassemia intermedia (TI). We aimed to determine whether there is a relationship of serum ferritin (SF) and alanine aminotransferase... -
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