- Transition Substitution of Desired Bases in Human Pluripotent Stem Cells with Base Editors: A Step-by-Step Guide
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Park JC, Kim KT, Jang HK, Cha HJ
- KMID: 2542835
- Int J Stem Cells.
- 2023 May;16(2):234-243.
- doi: 10.15283/ijsc22171
The recent advances in human pluripotent stem cells (hPSCs) enable to precisely edit the desired bases in hPSCs to be used for the establishment of isogenic disease models and autologous... -
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- Regenerative Effect of Adipose Derived Mesenchymal Stem Cells on Ganglion Cells in the Hypoxic Organotypic Retina Culture
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Dov MB, Krief B, Benhamou M, Klein A, Schwartz S, Loewenstein A, Barak A, Barzelay A
- KMID: 2542836
- Int J Stem Cells.
- 2023 May;16(2):244-249.
- doi: 10.15283/ijsc22041
Background and Objectives: To examine whether ischemic retinal ganglion cells (RGCs) will be salvaged from cell death by human adipose-derived mesenchymal stem cells (ADSCs) in an organotypic retina model. Methods and... -
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- The Role of SDF-1α-CXCR4/CXCR7 in Migration of Human Periodontal Ligament Stem Cells
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Xu J, Yang F, Luo S, Gao Y, Huang D, Zhang L
- KMID: 2542831
- Int J Stem Cells.
- 2023 May;16(2):180-190.
- doi: 10.15283/ijsc22053
Background and Objectives: Regenerative endodontic procedures (REPs) are a research hotspot in the endodontic field. One of the biggest problems of REPs is that it is difficult to realize regeneration... -
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- The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor
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Shang Z, Feng H, Xia L
- KMID: 2542827
- Int J Stem Cells.
- 2023 May;16(2):135-144.
- doi: 10.15283/ijsc22106
Background and Objectives: Melanocyte (MC), derived from neural crest stem cell (NCSC), are involved in the pro-duction of melanin. The mechanism by which NCSC differentiates to MC remains unclear. N6-methyladenosine... -
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- Exosomes from Tension Force-Applied Periodontal Ligament Cells Promote Mesenchymal Stem Cell Recruitment by Altering microRNA Profiles
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Chang M, Chen Q, Wang B, Zhang Z, Han G
- KMID: 2542833
- Int J Stem Cells.
- 2023 May;16(2):202-214.
- doi: 10.15283/ijsc21170
Background and Objectives: To investigate the role of exosomes from periodontal ligament cells (PDLCs) in bone marrow mesenchymal stem cell (BMSC) migration. Methods and Results: Human PDLCs were applied cyclic tension... -
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- Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
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Lee M, Seok J, Saha SK, Cho S, Jeong Y, Gil M, Kim A, Shin HY, Bae H, Do JT, Kim YB, Cho SG
- KMID: 2542834
- Int J Stem Cells.
- 2023 May;16(2):215-233.
- doi: 10.15283/ijsc22188
Background and Objectives: MYC, also known as an oncogenic reprogramming factor, is a multifunctional transcription factor that maintains induced pluripotent stem cells (iPSCs). Although MYC is frequently upregulated in various... -
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- Strategic Application of Epigenetic Regulators for Efficient Neuronal Reprogramming of Human Fibroblasts
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Fernandes GS, Singh RD, De D, Kim KK
- KMID: 2542829
- Int J Stem Cells.
- 2023 May;16(2):156-167.
- doi: 10.15283/ijsc22183
Background and Objectives: Cellular reprogramming in regenerative medicine holds great promise for treating patients with neurological disorders. In this regard, small molecule-mediated cellular conversion has attracted special attention because of... -
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- The Essential Function of miR-5739 in Embryonic Muscle Development
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Lee JH, Kim MS, Lee Js, Lee DH, Park C, Lee DH, Kim EY, Chung HM
- KMID: 2542828
- Int J Stem Cells.
- 2023 May;16(2):145-155.
- doi: 10.15283/ijsc22187
Background and Objectives: Embryologically, mesodermal development is closely related to the development of various organs such as muscles, blood vessels, and hearts, which are the main organs that make up... -
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- Cyclic Phytosphingosine-1-Phosphate Primed Mesenchymal Stem Cells Ameliorate LPS-Induced Acute Lung Injury in Mice
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Park Y, Jang J, Lee J, Baek H, Park J, Cha SR, Lee SB, Na S, Kwon JW, Hong SH, Yang SR
- KMID: 2542832
- Int J Stem Cells.
- 2023 May;16(2):191-201.
- doi: 10.15283/ijsc23001
Background and Objectives: O-cyclic phytosphingosine-1-phosphate (cP1P) is a synthetic chemical and has a structure like sphingosine-1-phosphate (S1P). S1P is known to promote cell migration, invasion, proliferation, and anti-apoptosis through hippocampal... -
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- The Calcineurin-Drp1-Mediated Mitochondrial Fragmentation is Aligned with the Differentiation of c-Kit Cardiac Progenitor Cells
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Rahman A, Li Y, Ismail NI, Chan TK, Li Y, Xu D, Zhou H, Ong SB
- KMID: 2542826
- Int J Stem Cells.
- 2023 May;16(2):123-134.
- doi: 10.15283/ijsc22141
Objective: The heart contains a pool of c-kit+ progenitor cells which is believed to be able to regenerate. The differentiation of these progenitor cells is reliant on different physiological cues.... -
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- Therapeutic Effect of Three-Dimensional Cultured Adipose-Derived Stem Cell-Conditioned Medium in Renal Ischemia-Reperfusion Injury
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Kim YS, Aum J, Kim BH, Jang MJ, Suh J, Suh N, You D
- KMID: 2542830
- Int J Stem Cells.
- 2023 May;16(2):168-179.
- doi: 10.15283/ijsc22137
Background and Objectives: We evaluated the effect of adipose-derived stem cell-derived conditioned medium (ADSC-CM) on the renal function of rats with renal ischemia-reperfusion injury (IRI)-induced acute kidney injury. Methods and Results:... -
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