- Measuring Glutathione Regeneration Capacity in Stem Cells
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Kim J, Gong YX, Jeong EM
- KMID: 2545234
- Int J Stem Cells.
- 2023 Aug;16(3):356-362.
- doi: 10.15283/ijsc23047
Glutathione (GSH) is a chief cellular antioxidant, affecting stem cell functions. The cellular GSH level is dynamically altered by the redox buffering system and transcription factors, including NRF2. Additionally, GSH... -
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- Extracellular Vesicles Derived from Mesenchymal Stem Cells as Cell-Free Therapy for Intrauterine Adhesion
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Li C, Hu Y
- KMID: 2545226
- Int J Stem Cells.
- 2023 Aug;16(3):260-268.
- doi: 10.15283/ijsc21177
Intrauterine adhesion (IUA) can occur after trauma to the basal layer of the endometrium, contributing to severe complications in females, such as infertility and amenorrhea. To date, the proposed therapeutic... -
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- Applications of Bioinspired Platforms for Enhancing Immunomodulatory Function of Mesenchymal Stromal Cells
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Kim OH, Jeon TJ, So YI, Shin YK, Lee HJ
- KMID: 2545225
- Int J Stem Cells.
- 2023 Aug;16(3):251-259.
- doi: 10.15283/ijsc22211
Mesenchymal stromal cells (MSCs) have attracted scientific and medical interest due to their self-renewing properties, pluripotency, and paracrine function. However, one of the main limitations to the clinical application of... -
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- Parathyroid Hormone-Related Protein Promotes the Proliferation of Patient-Derived Glioblastoma Stem Cells via Activating cAMP/PKA Signaling Pathway
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Guo Z, Huang T, Liu Y, Liu C
- KMID: 2545231
- Int J Stem Cells.
- 2023 Aug;16(3):315-325.
- doi: 10.15283/ijsc22097
Background and Objectives: Glioblastoma (GBM) is an aggressive primary brain tumor characterized by its hetero-geneity and high recurrence and lethality rates. Glioblastoma stem cells (GSCs) play a crucial role in... -
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- Peripheral Neuron-Organoid Interaction Induces Colonic Epithelial Differentiation via Non-Synaptic Substance P Secretion
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Che YH, Choi IY, Song CE, Park C, Lim SK, Kim JH, Sung SH, Park JH, Lee S, Kim YJ
- KMID: 2545227
- Int J Stem Cells.
- 2023 Aug;16(3):269-280.
- doi: 10.15283/ijsc23026
Background and Objectives: The colonic epithelial layer is a complex structure consisting of multiple cell types that regulate various aspects of colonic physiology, yet the mechanisms underlying epithelial cell differentiation... -
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- Notch Is Not Involved in Physioxia-Mediated Stem Cell Maintenance in Midbrain Neural Stem Cells
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Herrmann A, Meyer AK, Braunschweig L, Wagenfuehr L, Markert F, Kolitsch D, Vukicevic V, Hartmann C, Siebert M, Ehrhart-Bornstein M, Hermann A, Storch A
- KMID: 2545229
- Int J Stem Cells.
- 2023 Aug;16(3):293-303.
- doi: 10.15283/ijsc22168
Background and Objectives: The physiological oxygen tension in fetal brains (∼3%, physioxia) is beneficial for the maintenance of neural stem cells (NSCs). Sensitivity to oxygen varies between NSCs from different... -
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- Hypoxia Differentially Affects Chondrogenic Differentiation of Progenitor Cells from Different Origins
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Hammad M, Veyssiere A, Leclercq S, Patron V, Baugé C, Boumédiene K
- KMID: 2545230
- Int J Stem Cells.
- 2023 Aug;16(3):304-314.
- doi: 10.15283/ijsc21242
Background and Objectives: Ear cartilage malformations are commonly encountered problems in reconstructive surgery, since cartilage has low self-regenerating capacity. Malformations that impose psychological and social burden on one’s life are... -
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- Dissection of Cellular Communication between Human Primary Osteoblasts and Bone Marrow Mesenchymal Stem Cells in Osteoarthritis at Single-Cell Resolution
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Liu Y, Chen Y, Li XH, Cao C, Zhang HX, Zhou C, Chen Y, Gong Y, Yang JX, Cheng L, Chen XD, Shen H, Xiao HM, Tan LJ, Deng HW
- KMID: 2545233
- Int J Stem Cells.
- 2023 Aug;16(3):342-355.
- doi: 10.15283/ijsc22101
Background and Objectives: Osteoblasts are derived from bone marrow mesenchymal stem cells (BMMSCs) and play important role in bone remodeling. While our previous studies have investigated the cell subtypes and heterogeneity... -
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- Wedelolactone Promotes the Chondrogenic Differentiation of Mesenchymal Stem Cells by Suppressing EZH2
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Qin W, Yang L, Chen X, Ye S, Liu A, Chen D, Hu K
- KMID: 2545232
- Int J Stem Cells.
- 2023 Aug;16(3):326-341.
- doi: 10.15283/ijsc22046
Background and Objectives: Osteoarthritis (OA) is a degenerative disease that leads to the progressive destruction of articular cartilage. Current clinical therapeutic strategies are moderately effective at relieving OA-associated pain but cannot... -
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- Effect of Xenogeneic Substances on the Glycan Profiles and Electrophysiological Properties of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
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Kim YG, Yun JH, Park JW, Seong D, Lee Sh, Park KD, Lee HA, Park M
- KMID: 2545228
- Int J Stem Cells.
- 2023 Aug;16(3):281-292.
- doi: 10.15283/ijsc22158
Background and Objectives: Human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte (CM) hold great promise as a cellular source of CM for cardiac function restoration in ischemic heart disease. However, the use... -
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