- IL-4/IL-13 Cytokine and Receptor in Asthma
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Yang ES
- KMID: 2314355
- Pediatr Allergy Respir Dis.
- 2005 Mar;15(1):1-11.
Asthma is a chronic allergic inflammatory disease of lung. The initiation and progression of asthma is dependent on the cytokines interleukin (IL) -4 and IL-13 acting through related receptor complexes.... -
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- Studies on the Role of Interleukin-4 and Interleukin-13 in the Pathogenesis of Minimal Change Nephrotic Syndrome
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Cho BS
- KMID: 1989743
- Korean J Nephrol.
- 2001 May;20(3):375-380.
Minmal change nephrotic syndrome(MCNS) has been often associated with elevated IgE levels and referred to involve immune dysfunction. We have reported that MCNS may be a T-cell disorder involving abnormal... -
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- Role of IL-23 and Th17 Cells in Airway Inflammation in Asthma
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Nakajima H, Hirose K
- KMID: 1456191
- Immune Netw.
- 2010 Feb;10(1):1-4.
- doi: 10.4110/in.2010.10.1.1
Asthma is characterized by chronic airway inflammation with intense eosinophil and lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness. Accumulating evidence indicates that antigen-specific Th2 cells and their cytokines such as... -
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- The Role of Type 2 Innate Lymphoid Cells in Allergic Diseases
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- KMID: 2299449
- Korean J Asthma Allergy Clin Immunol.
- 2012 Dec;32(4):207-212.
Innate lymphoid cells have recently been identified to be a cell population that has morphology typical of lymphocytes but lacks rearranged antigen receptors. It can be classified into RORgammat innate... -
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- The Role of Cytokines in Allergy
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Lee CH
- KMID: 2131694
- J Rhinol.
- 1998 May;5(1):5-10.
Several pathophysiologic features of allergic inflammation, such as T(H) differentiation, the regulation of IgE, eosinophilia, mast cell proliferation, and cellular recruitment, are regulated by various cytokines. It has been of... -
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- A Study of the Expression of Cytokines and p53 in Nasal Polyps
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Ju MS, Kim CN, Hong YS
- KMID: 2131739
- J Rhinol.
- 1999 Nov;6(2):91-98.
BACKGROUND AND OBJECTIVES: Nasal polyps are a condition of uncertain etiology. Cytokines are thought to play a role in nasal polyps in vitro, but in vivo studies on the patterns... -
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- Production of Interleukin-5, Interleukin-13 and Interferon-gamma in Peripheral Blood CD8+T Cells from Children with Wheezing
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Lee MH, Moon S, Jang JH, Chung MS, Kim E, Yoon JS, Kim HH, Lee JS
- KMID: 2314888
- Pediatr Allergy Respir Dis.
- 2008 Sep;18(3):228-235.
PURPOSE: Our objective was to investigate the role of CD8+T cells in pathogenesis of wheezing in children with atopic nature. METHODS: Twelve atopic wheezers, 8 nonatopic wheezers, 8 disease controls and... -
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- Differential Expressions of IL-3 and FcepsilonRI in the Peripheral Blood Mononuclear Cells and Lesional Skin of Patients with Extrinsic Atopic Dermatitis and Intrinsic Atopic Dermatitis
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Jin S, Noh S, Bae BG, Park CO, Lee KH
- KMID: 1451617
- Korean J Dermatol.
- 2011 Jun;49(6):491-498.
BACKGROUND: A small subgroup of atopic dermatitis (AD) patients show low total and allergen-specific immunoglobulin (IgE) levels. This subgroup has been termed 'intrinsic' AD (IAD) as compared to its counterpart... -
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- Characterization of Th2 Cytokines, IL-5, IL-10 and IL-13, in Otitis Media with Effusion: Comparison of Allergy and Non Allergy
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Jung MK, Lee CH, Kim SW, Chang KH, Yeo SW
- KMID: 2276009
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Jun;46(6):459-463.
BACKGROUND AND OBJECTIVES: While it has been reasonably well demonstrated that allergy is a risk factor for patients of otitis media with effusion (OME), the causal mechanism is not well... -
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- Responses of Pro-Inflammatory and Anti-Inflammatory Cytokines with Clonidine Premedication in Patients Undergoing Spinal Surgery
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Kim MH, Kim JS, Ahn HJ
- KMID: 2237622
- Korean J Anesthesiol.
- 1998 Dec;35(6):1080-1088.
- doi: 10.4097/kjae.1998.35.6.1080
BACKGROUND: As immune mediators, cytokines are thought to regulate many biological functions. Changes in cytokine response were found in stressful conditions including surgery. Our aim was to study the effects... -
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- Expression of mRNA of GATA-3 and T-bet in the peripheral blood mononuclear cells of atopic asthmatics
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Jee YK, Kim YS, Park JS, Lee KY
- KMID: 2252688
- Korean J Med.
- 2004 Jan;66(1):67-74.
BACKGROUND: It is well known that the expression of Th2 cytokines are up-regulated in the atopic asthma. The study was to investigate the expression of transcription factors, such as GATA-3,... -
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- Analysis of Intraocular Cytokines According to Progression of Diabetic Retinopathy and Macular Edema in Diabetic Patients
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Sin BH, Kim JY, Park JY, Park SP
- KMID: 2216943
- J Korean Ophthalmol Soc.
- 2013 Apr;54(4):618-626.
- doi: 10.3341/jkos.2013.54.4.618
PURPOSE: To investigate the relationship between the aqueous concentrations of cytokines, chemokine, VEGF and the severity of diabetic retinopathy and diabetic macular edema. METHODS: Sixty eyes with diabetic retinopathy and diabetic... -
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- Comparative Analysis of Human Epidermal and Peripheral Blood gammadelta T Cell Cytokine Profiles
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Kim K, Han J, Lee TR, Shin DW, Chang H, Cho AR, Choi SJ, Jo SJ, Kwon O
- KMID: 2368150
- Ann Dermatol.
- 2014 Jun;26(3):308-313.
BACKGROUND: Human epidermal gammadelta T cells are known to play crucial roles in the defense and homeostasis of the skin. However, their precise mechanism of action in skin inflammation remains... -
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- The effect of IL-13 on adhesion of eosinophils to vascular endothelial cells
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Song SH, Kim KH, Moon HS, Song JS, Park SH
- KMID: 2286075
- J Asthma Allergy Clin Immunol.
- 1999 Feb;19(1):31-41.
BACKGROUND: Infiltration of eosinophils and activated T cells into the airway is a characteristic feature of allergic inflammation such as asthma. IL-4 has been shown to mediate adhesion of eosinophils and T... -
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- IL-13 And IL-5 in Induced Sputum in Patients with Eosinophilic Bronchitis and Asthma: an Association with Airway Hyperresponsiveness
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- KMID: 2299669
- Korean J Asthma Allergy Clin Immunol.
- 2005 Sep;25(3):210-216.
BACKGROUND: Experimental studies on asthma have indicated that IL-13 induces airway hyperreactivity (AHR). However, it remains unproven that IL-13 is responsible for AHR of asthmatics. Eosinophilic bronchitis (EB) shows normal... -
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- Serum Eotaxin and Interleukin-13 Level in Patients with Allergic Rhinitis
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Lee KC
- KMID: 2131796
- J Rhinol.
- 2002 Nov;9(1, 2):24-29.
BACKGROUND AND OBJECTIVES: Eosinophils play a central role in the development of allergic diseases, including asthma, nasal allergy, and atopic dermatitis. Eosinophil migration in vivo is regulated by many cytokines... -
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- No evidence of association between interleukin-13 gene polymorphism in aspirin intolerant chronic urticaria
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Palikhe NS, Kim SH, Choi GS, Ye YM, Park HS
- KMID: 2133797
- Allergy Asthma Immunol Res.
- 2009 Oct;1(1):36-40.
- doi: 10.4168/aair.2009.1.1.36
Aspirin-intolerant chronic urticaria (AICU) is a common condition among the chronic urticaria population, but the genetic mechanism is not yet understood. In this study, the genotypes and haplotypes of three... -
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- Emerging Endotypes of Chronic Rhinosinusitis and Its Application to Precision Medicine
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Kim DW, Cho SH
- KMID: 2378192
- Allergy Asthma Immunol Res.
- 2017 Jul;9(4):299-306.
- doi: 10.4168/aair.2017.9.4.299
Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease with various underlying pathophysiologic mechanisms which translate to endotypes, in contrast to clinical phenotypes or histological subtypes. Defining endotypes can help clinicians... -
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- STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation
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Krishnamurthy P, Kaplan MH
- KMID: 2349881
- Immune Netw.
- 2016 Aug;16(4):201-210.
- doi: 10.4110/in.2016.16.4.201
Allergic inflammation requires the orchestration of altered gene expression in the target tissue and in the infiltrating immune cells. The transcription factor STAT6 is critical in activating cytokine gene expression... -
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- Interleukin-13 Increases Podocyte Apoptosis in Cultured Human Podocytes
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Lee KH, Oh JY, Seong SB, Ha TS, Shin JI
- KMID: 2435351
- Child Kidney Dis.
- 2018 Apr;22(1):22-27.
- doi: 10.3339/jkspn.2018.22.1.22
PURPOSE: Podocytes are important architectures that maintain the crucial roles of glomerular filtration barrier functions. Despite this structural importance, however, the mechanisms of the changes in podocytes that can be... -
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