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The distribution of inositol 1,4,5-trisphosphate 3-kinase in rat cerebellum

Lee HK, Ko JP, Hwang SJ, Suh YS

  • KMID: 1686671
  • Korean J Anat.
  • 1993 Mar;26(1):94-102.
No abstract available.
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Distribution of inositol 1,4,5-trisphosphate 3-kinase in the cat brain by immunohistochemical study

Kim DH, Kim H, Hwang SJ, Hong HN, Suh YS

  • KMID: 1686601
  • Korean J Anat.
  • 1993 Dec;26(4):378-389.
No abstract available.
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Immunohistochemical study of the distribution of inositol phospholipid-specific phospholipase C-? in the rat brain

Park JM, Kim H, Ko JP, Suh YS

  • KMID: 1686670
  • Korean J Anat.
  • 1993 Mar;26(1):80-93.
No abstract available.
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Immunohistochemical study of inositol phospholipid-specific phospholipase C in the rat liver and kidney

Kim DS, Hwang SJ, Kim DH, Suh YS

  • KMID: 1686672
  • Korean J Anat.
  • 1993 Mar;26(1):103-115.
No abstract available.
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The effect of kainic acid induced convulsions on the expression of inositol 1,4,5-trisphosphate receptor mRNA in the rat brain

Kim H, Ko SH, Kim CM, Rhyu IJ, Chung HS, Kim DY, Suh YS

  • KMID: 1937876
  • Korean J Anat.
  • 1998 Oct;31(5):645-654.
In this study, the effect of systemic administration of kainic acid (KA) on the expression of inositol 1,4,5-trisphosphate receptor mRNA in the rat brain was investigated with in situ hybridization...
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Determination of Urinary Myo-/Chiro-Inositol Ratios from Korean Diabetes Patients

Jung TS, Hahm JR, Kim JJ, Jung JH, Kang MY, Moon SW, Lee KW, Kim HC, Lee JD, Kim JH, Kim DR, Chung SI

Of two major forms (myo- and chiro-inositol) of inositols, only chiro-inositol enhances the activity of proteins involved in intracellular glucose metabolism. This study aims to determine the urinary myo-/chiro-inositol ratio...
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Purification of Inositol Triphosphate Kinase from Bovine Brain

Kim HH, Lee JT

Inositol 1,4,5-triphosphate(InsP,) is a second messenger for obilizing intracellular Cal'. It can be dephosphorylated by soluble and particulate forms on InsP, 5-phosphatase, or phosphorylated to produce inositol 1,3,4,5-tetrakisphosphate(InsP,) by InsP,...
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Apoptotic effect of IP6 was not enhanced by co-treatment with myo-inositol in prostate carcinoma PC3 cells

Kim HJ, Jang YM, Kim H, Kwon YH

  • KMID: 2313314
  • Nutr Res Pract.
  • 2007 Sep;1(3):195-199.
Inositol hexaphosphate (IP6) is a major constituent of most cereals, legumes, nuts, oil seeds and soybean. Previous studies reported the anticancer effect of IP6 and suggested that co-treatment of IP6...
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Calcium Signaling in Salivary Secretion

Kim JM, Lee SW, Park K

Calcium has versatile roles in diverse physiological functions. Among these functions, intracellular Ca²⁺ plays a key role during the secretion of salivary glands. In this review, we introduce the diverse...
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Differential effect of homocysteic acid and cysteic acid on changes of inositol phosphates and (Ca2+)i in rat cerebellar granule cells

Kim WK, Pae YS

  • KMID: 2071522
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):41-48.
The present study was undertaken to characterize homocysteic acid (HCA)-and cysteic acid (CA)mediated formation of inositol phosphates (InsP) in primary culture of rat cerebellar granule cells. HCA and CA stimulated InsP formation in...
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EGF-stimulated aldosterone secretion is mediated by tyrosine phosphorylation but not by phospholipase C in cultured porcine adrenal glomerulosa cells

Kim SY, Park DJ, Lee HK

We examined the effect of EGF and angiotensin II (AII) on the formation of inositol phosphates and aldosterone secretion, and observed the role of tyrosine phosphorylation in EGF or...
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TonEBP and SMIT expression in human placenta

Shin JA, Kwon HM, Han KH, Lee HY

Tonicity-responsive enhancer binding protein (TonEBP) is a signal transcription factor of transporters such as sodium-myo-inositol cotransporter (SMIT), aldose reductase. TonEBP has a variety of functions such as control of intracellular...
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Inositol 5'-phosphatase, SHIP1 interacts with phospholipase C-gamma1 and modulates EGF-induced PLC activity

Song M, Kim MJ, Ha S, Park JB, Ryu SH, Suh PG

  • KMID: 1056227
  • Exp Mol Med.
  • 2005 Jun;37(3):161-168.
Phospholipase C-gamma1, containing two SH2 and one SH3 domains which participate in the interaction between signaling molecules, plays a significant role in the growth factor-induced signal transduction. However, the role...
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The Relationship between Change of Lymphocyte Inositol Monophosphatase mRNA Level by Lithium and Clinical Course in Bipolar Affective Disorder

Kim SH, Lee MS, Lee JH

  • KMID: 2142164
  • J Korean Soc Biol Psychiatry.
  • 2001 Jun;8(1):96-105.
OBJECTIVE: Lithium inhibits the action of inositol monophosphatase(IMPase) in phosphoinositide(PI) signal transduction system at therapeutically relevant concentration. The depletion of inositol by lithium itself cannt explain the lithium's therapeutic effect....
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The effect of Ni2+ on the intracellular Ca2+ increase of the mouse early 2-cell embryos

Yoon SY, Lee EM, Bae IH

  • KMID: 2304560
  • Korean J Fertil Steril.
  • 2003 Dec;30(4):269-280.
OBJECTIVE: We reported the overcoming effect of Ni2+ on the in vitro 2-cell block of mouse embryos. In this study, we aim to investigate whether Ni2+ should induce intracellular Ca2+...
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The Affinity of Calmodulin-Affigel for Inositol Triphosphate Kinase From Bovine Brain

Lim SW, Kim JH

The one event on signaling mechanism is the cleavage by adenyl cyclase of ATP into second messenger, cyclic AMP. The other transfer system of inositol metabolism, it is widely recognized...
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Effects of Inositol 1,4,5-triphosphate on Osteoclast Differentiation in RANKL-induced Osteoclastogenesis

Son A, Kim MS, Jo H, Byun HM, Shin DM

The receptor activator of NF-kappaB ligand (RANKL) signal is an activator of tumor necrosis factor receptor-associated factor 6 (TRAF6), which leads to the activation of NF-kappaB and other signal transduction...
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Effect of Inositol-phosphatase on Fc Receptor-mediated Phagocytosis of Macrophages

Kim JH

BACKGROUND: Fc receptor-mediated phagocytosis is a complex process involving the activation of kinases and phosphatases. FcgammaRIIB has been known to transduces inhibitory signals through an immunoreceptor tyrosine-based inhibitory motif (ITIM)...
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Signal Transduction Mechanisms Mediating Surfactant Phospholipid Secretion in Isolated Type II Cell

Park SS

  • KMID: 2317983
  • Tuberc Respir Dis.
  • 1996 Apr;43(2):123-127.
Secretion of surfactant phospholipid can be stimulated by a variety of agonists acting via at least three different signal transduction mechanisms. These include the adenylate cyclase system with activation of...
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The clinical study to evaluate the safety and efficacy of D-chiro-inositol in patients with type 2 diabetes

Ku BJ, Kim HJ, Park KS

  • KMID: 2256471
  • Korean J Med.
  • 2007 Jan;72(1):29-36.
BACKGROUND: D-chiro-inositol (DCI) is a postreceptor signaling molecule of insulin action. Blood and urine levels of DCI were decreased in diabetic animals. Treatment of DCI improves insulin resistance and normalizes...
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