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Current Advances in Three-Dimensional Tissue/Organ Printing

Park JH, Jang J, Lee JS, Cho DW

Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues,...
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Role of Antioxidants in Assisted Reproductive Techniques

Agarwal A, Majzoub A

Oxidative stress (OS) has been recognized as a significant cause of suboptimal assisted reproductive outcome. Many of the sperm preparation and manipulation procedures that are necessary in the in vitro...
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Recent Advances in Biosensors for Nucleic Acid and Exosome Detection

Fu Z, Lu YC, Lai JJ

Biosensors are analytical devices for biomolecule detection that compromise three essential components: recognition moiety, transducer, and signal processor. The sensor converts biomolecule recognition to detectable signals, which has been applied...
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In Vitro Diagnostic Testing for Antibiotic Allergy

Doña I, Torres MJ, Montañez , Fernández TD

Allergy to antibiotics is an important worldwide problem, with an estimated prevalence of up to 10% of the population. Reaction patterns for different antibiotics have changed in accordance with consumption...
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Study on methodology for the assessment of internal and marginal adaptation on fixed dental prosthesis

Pyo SW, Lee JJ, Han JS, Lim YJ

This article is to review various methods used to investigate internal and marginal adaptation of fixed dental prostheses, and to summarize a merit, worth, and limitation of each method, using...
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Potency and plasma protein binding of drugs in vitro—a potentially misleading pair for predicting in vivo efficacious concentrations in humans

Yim DS

In drug discovery or preclinical stages of development, potency parameters such as ICâ‚…â‚€, K(i), or K(d) in vitro have been routinely used to predict the parameters of efficacious exposure (AUC,...
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Culture of Nail Matrix Cells

Yoo JH, Eun HC, Lee YH

BACKGROUND: In vitro epidermal keratinocytes(EKs) culture systems are widely used in studying skin biology and differentiation. Recently a monolayer culture method of nail matrix cells(NMCs) has been developed. OBJECTIVE: This study...
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A review of biocompatibility of zirconia: In vitro experiment

Suh DW, Kim YK, Yi YJ

Increasing demands for zirconia material in clinics, assessment of biocompatibility of zirconia is essential. In this article, a review of in vitro studies of zirconia compatibility was performed. Zirconia showed...
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The Effect of Calcitonin Gene-Related Peptide on Hair Growth in Vitro

Suh DH, Eun HC

BACKGROUND: Calcitonin gene-related peptide(CGRP)-containing nerve fibers are widely distributed in the skin including the area around hair follicles. OBJECTIVE: This study was undertaken to investigate the effect of CGRP on normal...
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Performance of disposable endoscopic forceps according to the manufacturing techniques

Kwon CI, Kim G, Moon JP, Yun H, Ko WJ, Cho JY, Hong SP

BACKGROUND/AIMS: Recently, to lower the production costs and risk of infection, new disposable biopsy forceps made using simple manufacturing techniques have been introduced. However, the effects of the manufacturing techniques...
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Human ex vivo and in vitro disease models to study food allergy

Hung L, Obernolte , Sewald K, Eiwegger T

Food allergy is a growing global public health concern. As treatment strategies are currently limited to allergen avoidance and emergency interventions, there is an increasing demand for appropriate models of...
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Successful in vitro fertilization pregnancy and delivery after a fertility-sparing laparoscopic operation in a patient with a papillary thyroid carcinoma arising from a mature cystic teratoma

Hong K, Han AK, Kim ML, Yun BS, Jun HS, Seong SJ, Shim JY

Malignant transformation of ovarian mature cystic teratomas is rare, and papillary thyroid cancer occurs in 0.1%–0.3% of ovarian teratomas that undergo malignant transformation. We describe a case of successful in...
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Optogenetic and Chemogenetic Approaches for Studying Astrocytes and Gliotransmitters

Bang J, Kim HY, Lee H

The brain consists of heterogeneous populations of neuronal and non-neuronal cells. The revelation of their connections and interactions is fundamental to understanding normal brain functions as well as abnormal changes...
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Retrospective growth kinetics and radiosensitivity analysis of various human xenograft models

Lee JY, Kim MS, Kim EH, Chung N, Jeong YK

The purpose of this study was to delineate the various factors that affect the growth characteristics of human cancer xenografts in nude mice and to reveal the relationship between the...
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Effect of Several Growth Factors on Hair Follicle Growth in Hair Follicle Organ Culture

Kim JA, Eun HC

BACKGROUND: Factors that regulate hair matrix cell division within the hair follicles and control hair growth cycle have been poorly understood untill now. One of the main.causes seems to be...
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In vitro evaluation methods on adaptation of fixed dental prosthesis

Lee H, Lee DH, Lee KB

Clinically, the fit of fixed prosthesis is an essential element for successful restoration. The fit of prosthesis is largely classified into marginal fit and internal fit, and various methods to...
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Cryopreservation of in vitro matured oocytes after ex vivo oocyte retrieval from gynecologic cancer patients undergoing radical surgery

Park CW, Lee SH, Yang KM, Lee IH, Lim KT, Lee KH, Kim TJ

OBJECTIVE: The aim of this study was to report a case series of in vitro matured (IVM) oocyte freezing in gynecologic cancer patients undergoing radical surgery under time constraints as...
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Effects of sperm insemination on the final meiotic maturation of mouse oocytes arrested at metaphase I after in vitro maturation

Yoon J, Juhn KM, Yoon SH, Ko Y, Lim JH

OBJECTIVE: The aims of this study were to investigate whether fertilization could induce the resumption of meiosis in mouse oocytes arrested at metaphase I (MI) after in vitro maturation (IVM),...
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Morphological transformation induced by silver nanoparticles in a Balb/c 3T3 A31-1-1 mouse cell model to evaluate in vitro carcinogenic potential

Choo W, Moon B, Song S, Oh SM

Carcinogenesis is a complex process involved in genotoxic and non-genotoxic pathways. The carcinogenic potential of silver nanoparticles (AgNPs) has been predicted by examining their genotoxic effects using several in vitro...
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Enrichment and In Vitro Culture of Spermatogonial Stem Cells from Pre-Pubertal Monkey Testes

Kim YH, Kang HG, Kim BJ, Jung SE, Karmakar P, Kim SM, Hwang S, Ryu BY

Spermatogonial stem cells (SSCs) are essential for spermatogenesis throughout the lifespan of the male. However, the rarity of SSCs has raised the need for an efficient selection method, but little...
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