- Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes
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Lee EY, Hwang S, Lee YH, Lee SH, Lee YM, Kang HP, Han E, Lee W, Lee BW, Kang ES, Cha BS, Lee HC
- KMID: 2427119
- Yonsei Med J.
- 2017 Mar;58(2):312-318.
- doi: 10.3349/ymj.2017.58.2.312
PURPOSE: Metformin can reduce diabetes-related complications and mortality. However, its use is limited because of potential lactic acidosis-associated adverse effects, particularly in renal impairment patients. We aimed to investigate the... -
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- What is the Clinical Significance of Initial Lactate Measurement Compared to Carboxyhemoglobin Measurement in Carbon Monoxide Poisoning?
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Hwang SG, Jin SC, Choi WI, Jeon JC, Kim TK
- KMID: 2394397
- J Korean Soc Emerg Med.
- 2017 Oct;28(5):484-492.
- doi: 10.0000/jksem.2017.28.5.484
PURPOSE: This study was performed to compare clinical significance between lactate and carboxyhemoglobin (COHb) in a patient with carbon monoxide (CO) poisoning. METHODS: We conducted a 13-year retrospective study on CO... -
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- The First Korean case of combined oxidative phosphorylation deficiency-17 diagnosed by clinical and molecular investigation
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Kim YA, Kim YM, Lee YJ, Cheon CK
- KMID: 2398890
- Korean J Pediatr.
- 2017 Dec;60(12):408-412.
- doi: 10.3345/kjp.2017.60.12.408
Combined oxidative phosphorylation deficiency-17 (COXPD-17) is very rare and is caused by homozygous or compound heterozygous mutations in the ELAC2 gene on chromosome 17p12. The ELAC2 gene functions as a... -
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- Anti-Diabetic Effect of Cotreatment with Quercetin and Resveratrol in Streptozotocin-Induced Diabetic Rats
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Yang DK, Kang HS
- KMID: 2429052
- Biomol Ther.
- 2018 Mar;26(2):130-138.
- doi: 10.4062/biomolther.2017.254
Quercetin and resveratrol are known to have beneficial effects on the diabetes and diabetic complication, however, the effects of combined treatment of these compounds on diabetes are not fully revealed.... -
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- Clinical Application of the Quick Sepsis-Related Organ Failure Assessment Score at Intensive Care Unit Admission in Patients with Bacteremia: A Single-Center Experience of Korea
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Na HJ, Jeong ES, Kim I, Kim WY, Lee K
- KMID: 2391184
- Korean J Crit Care Med.
- 2017 Aug;32(3):247-255.
- doi: 10.4266/kjccm.2017.00241
BACKGROUND: We evaluated the clinical usefulness of the quick Sepsis-Related Organ Failure Assessment (qSOFA) score (based on the 2016 definition of sepsis) at intensive care unit admission in Korean patients... -
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- Prognostic Value of Blood Lactate for Mortality of Acutely Poisoned Patients in Emergency Department
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Kim HR, Kang MJ, Kim YH, Lee JH, Cho KW, Hwang SY, Lee DW
- KMID: 2328235
- J Korean Soc Clin Toxicol.
- 2016 Jun;14(1):16-25.
PURPOSE: Patients suffering from acute poisoning by different substances often visit the emergency department (ED) and receive various prognoses according to the toxic material and patients' condition. Hyperlactatemia, which is... -
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- Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits
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Bárcena-Varela S, MartÃnez-de-Tejada G, Martin L, Schuerholz T, Gil-Royo A, Fukuoka S, Goldmann T, Droemann D, Correa W, Gutsmann T, Brandenburg K, Heinbockel L
- KMID: 2386965
- Exp Mol Med.
- 2017 Jun;49(6):e345.
- doi: 10.1038/emm.2017.75
Sepsis, which is induced by severe bacterial infections, is a major cause of death worldwide, and therapies combating the disease are urgently needed. Because many drugs have failed in clinical... -
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- Korean Shock Society septic shock registry: a preliminary report
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Shin TG, Hwang SY, Kang GH, Kim WY, Ryoo SM, Kim K, Jo YH, Chung SP, Joo YS, Beom JH, Choi SH, Yoon YH, Kwon WY, Lim TH, Han KS, Choi HS, Suh GJ
- KMID: 2401243
- Clin Exp Emerg Med.
- 2017 Sep;4(3):146-153.
- doi: 10.15441/ceem.17.204
OBJECTIVE: To evaluate the clinical characteristics, therapeutic interventions, and outcomes of patients with septic shock admitted to the emergency department (ED). METHODS: This study was a preliminary, descriptive analysis of a... -
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