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Biopolymeric In Situ Hydrogels for Tissue Engineering and Bioimaging Applications

Sontyana A, Mathew AP, Cho KH, Uthaman S, Park IK

BACKGROUND: Biopolymeric in situ hydrogels play a crucial role in the regenerative repair and replacement of infected or injured tissue. They possess excellent biodegradability and biocompatibility in the biological system,...
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Injectable Hydrogels for Regenerative Medicine

Kim BS, Cho CS

No abstract available.
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Electrostatically Interactive Injectable Hydrogels for Drug Delivery

Seo JY, Lee B, Kang TW, Noh JH, Kim MJ, Ji YB, Ju HJ, Min BH, Kim MS

BACKGROUND: Several injectable hydrogels have been developed extensively for a broad range of biomedical applications. Injectable hydrogels forming in situ through the change in external stimuli have the distinct properties...
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In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative Medicine

Park KM, Park KD

BACKGROUND: Polymeric hydrogels are extensively used as promising biomaterials in a broad range of biomedical applications, including tissue engineering, regenerative medicine, and drug delivery. These materials have advantages such as...
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Bone Morphogenetic Protein-2 Sustained Delivery by Hydrogels with Microspheres Repairs Rabbit Mandibular Defects

Song WY, Liu GM, Li J, Luo YG

Mandible defect is a difficult issue in dental surgery owing to limited therapeutic options. Recombinant human bone morphogenetic protein-2 (rhBMP2) is osteoinductive in bone regeneration. This article prepared chitosan/collagen hydrogels...
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Advances in the design of macroporous polymer scaffolds for potential applications in dentistry

Bencherif , Braschler , Renaud P

  • KMID: 2329644
  • J Periodontal Implant Sci.
  • 2013 Dec;43(6):251-261.
A paradigm shift is taking place in medicine and dentistry from using synthetic implants and tissue grafts to a tissue engineering approach that uses degradable porous three-dimensional (3D) material hydrogels...
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Click Chemistry-Based Injectable Hydrogels and Bioprinting Inks for Tissue Engineering Applications

Gopinathan J, Noh I

BACKGROUND: The tissue engineering and regenerative medicine approach require biomaterials which are biocompatible, easily reproducible in less time, biodegradable and should be able to generate complex three-dimensional (3D) structures to...
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Atelocollagen-based Hydrogels Crosslinked with Oxidised Polysaccharides as Cell Encapsulation Matrix for Engineered Bioactive Stromal Tissue

Luca A, Butnaru M, Maier SS, Knieling L, Bredetean , Verestiuc , Dimitriu D, Popa M

Tissue stroma is responsible for extracellular matrix (ECM) formation and secretion of factors that coordinate the behaviour of the surrounding cells through the microenvironment created. It's inability to spontaneously regenerate...
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Synthetic Hydrogels with Stiffness Gradients for Durotaxis Study and Tissue Engineering Scaffolds

Whang M, Kim J

Migration of cells along the right direction is of paramount importance in a number of in vivo circumstances such as immune response, embryonic developments, morphogenesis, and healing of wounds and...
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BONE REGENERATION WITH INJECTABLE MPEG-PCL DIBLOCK COPOLYMER AND BONE MARROW MESENCHYMAL STEM CELL

Jeong YM, Lee TH, Park JK, Kim W, Shin JH, Lee ES, Rim JS, Jang HS

  • KMID: 2005090
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2010 Jan;32(1):9-15.
AIM OF THE STUDY: As an injectable scaffold, MPEG-PCL diblock copolymer was applied in bone tissue engineering. In vivo bone formation was evaluated by soft X-ray, histology based on the...
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The Alginate Layer for Improving Doxorubicin Release and Radiolabeling Stability of Chitosan Hydrogels

Kwon JI, Lee CM, Jeong HS, Oh PS, Hwang H, Lim ST, Sohn MH, Jeong HJ

PURPOSE: Chitosan hydrogels (CSH) formed through ionic interaction with an anionic molecule are suitable as a drug carrier and a tissue engineering scaffold. However, the initial burst release of drugs...
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Alginate-Hyaluronic Acid-Collagen Composite Hydrogel Favorable for the Culture of Chondrocytes and Their Phenotype Maintenance

Mahapatra , Jin GZ, Kim HW

Articular cartilage has limited regeneration capacity, thus significant challenge has been made to restore the functions. The development of hydrogels that can encapsulate and multiply cells, and then effectively maintain...
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Fabrication of Microchannels and Evaluation of Guided Vascularization in Biomimetic Hydrogels

Lee J, Lee SH, Lee BK, Park SH, Cho YS, Park Y

BACKGROUND: The fabrication of microchannels in hydrogel can facilitate the perfusion of nutrients and oxygen, which leads to guidance cues for vasculogenesis. Microchannel patterning in biomimetic hydrogels is a challenging...
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Effects of Type I Collagen Concentration in Hydrogel on the Growth and Phenotypic Expression of Rat Chondrocytes

Jin GZ, Kim HW

It is controversial whether type I collagen itself can maintain and improve chondrogenic phenotype of chondrocytes in a three-dimensional (3D) environment. In this study, we examined the effect of type...
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Microfluidic Spinning of the Fibrous Alginate Scaffolds for Modulation of the Degradation Profile

Mun CH, Hwang JY, Lee SH

In tissue engineering, alginate has been an attractive material due to its biocompatibility and ability to form hydrogels, unless its uncontrollable degradation could be an undesirable feature. Here, we developed...
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Comparison of Angiogenic Activities of Three Neuropeptides, Substance P, Secretoneurin, and Neuropeptide Y Using Myocardial Infarction

Lee J, Song M, Kim J, Park Y

BACKGROUND: The interplay between neurogenesis and angiogenesis is crucial during the development mediated by neuro-angiogenic morphogens. In particular, the angiogenic activity of neuropeptides and their role in tissue regeneration have...
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Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

Ugi S, Maegawa H, Morino K, Nishio Y, Sato T, Okada S, Kikkawa Y, Watanabe T, Nakajima H, Kashiwagi

BACKGROUND: Management of postprandial hyperglycemia is a key aspect in diabetes treatment. We developed a novel system to measure glucose area under the curve (AUC) using minimally invasive interstitial fluid...
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Synthesis and Biocompatibility Characterizations of in Situ Chondroitin Sulfate–Gelatin Hydrogel for Tissue Engineering

Bang S, Jung UW, Noh I

Novel hydrogel composed of both chondroitin sulfate (CS) and gelatin was developed for better cellular interaction through two step double crosslinking of N-(3-diethylpropyl)-N-ethylcarbodiimide hydrochloride (EDC) chemistries and then click chemistry....
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Hard tissue regeneration using bone substitutes: an update on innovations in materials

Sarkar SK, Lee BT

Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches...
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Combined Skin Moisturization of Liposomal Serine Incorporated in Hydrogels Prepared with Carbopol ETD 2020, Rhesperse RM 100 and Hyaluronic Acid

Kim H, Ro J, Barua S, Hwang DS, Na SJ, Lee HS, Jeong JH, Woo S, Kim H, Hong B, Yun G, Kim JH, Yoon YH, Park MG, Kim J, Sohn UD, Lee J

We investigated the combined moisturizing effect of liposomal serine and a cosmeceutical base selected in this study. Serine is a major amino acid consisting of natural moisturizing factors and keratin,...
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