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A Case of Invasive Mole Initially Presenting with Symptoms of Brain Metastasis

Chung TY, Ryu HS, Chang KH, Lee EJ, Joo HJ, Ahn YH, Oh KS, Kim JW

  • KMID: 1675684
  • Korean J Gynecol Oncol Colposc.
  • 1996 Jun;7(2):152-157.
Invasive mole is a malignant form of hydatidiform mole and can be seen occasionally. It invades the myometrium, adjacent structures and metastasizes distantly. It can initially appear with symptoms of...
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A Case of Invasive Mole with Uterine Rupture Presenting as a Hemoperitoneum

Kim JY, Kim KH, Shin BS, Ahn KH, Lee JS, Yoon MS

  • KMID: 1615592
  • Korean J Gynecol Oncol Colposc.
  • 2003 Mar;14(1):61-65.
Invasive mole is defined as the invasion of molar villi into myometrium or the metastasis on several organs from hydatidiform mole. It is not understood accurately, because this disease is...
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Telomerase Activity in Gestational Trophoblastic Disease

Bae SN, Jung JK, Choi EA, Kim JS, Kim DJ, Ahn HY, Kim SJ

  • KMID: 2269580
  • Korean J Obstet Gynecol.
  • 1998 Jun;41(6):1704-1708.
The purpose of this study was to evaluate the significance of telomerase activity in gestational trophoblastic disease and the association of telomerase activity in complete hydatidiform mole and subsequent development...
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10 Year's Expreience on Gestational Trophoblastic Disease

Chyu EH, Yoo GS, Kim WG, Park UD

  • KMID: 1675677
  • Korean J Gynecol Oncol Colposc.
  • 1996 Jun;7(2):84-92.
For the clinical analysis and evaluation on the patients with gestational trophoblastic disease(GTD), a study was done retrospectively on 114 patients with GTD(60 in Hydatidiform mole, 10 in invasive mole,...
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Metastatic gestational trophoblastic neoplasm presenting as spontaneous renal and cerebral hemorrhage with low titer of HCG: A case report of an unusual case

Moon HH, Kim SM, Moon JH, Kang WD, Choi HS

  • KMID: 2393152
  • Korean J Obstet Gynecol.
  • 2012 Oct;55(10):766-771.
Gestational trophoblastic neoplasm includes tumor spectrum of four entities: hydatidiform mole (complete and partial), invasive mole, choriocarcinoma and placental site trophoblastic tumor. The hydatidiform mole is usually benign, but it...
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An Immunohistochemical Study on the Localization and Intensity of Human Chorionic Gonadotropin, Human Placental Lactogen and Pregnancy Specific Beta-1 Glycoprotein in Gestational Trophoblastic Neoplasms by Immunoperocidase Method

Lee MK, Han WS, Kim OK

Fourty-six cases of gestational trophoblastic neoplasms (32 cases of hydatidiform mole; 4 cases of invasive mole; 10 cases of choriocarcinoma) and five cases of normal pregnancy as control group were...
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The Diagnostic Value of PCR in Gestational Trophoblastic Disease

Lee YG, Lee DJ, Lee SH

  • KMID: 1924480
  • Korean J Obstet Gynecol.
  • 1997 Feb;40(2):395-407.
This study was conducted to assess the value of DNA diagnosis of gestational trophoblastic disease using polymerase chain reaction method. The 3 genetic loci including a variable number of tandem...
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Giant invasive mole presenting as a cause of abdominopelvic mass in a perimenopausal woman: An unusual presentation of a rare pathology

Akyol A, Simşek M, Üçer O

Invasive mole is a benign gestational trophoblastic disease that arises from the myometrial invasion of any gestational event via direct extension through tissue or vascular structures. Invasive mole (and other...
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Metastatic Invasive Mole in the Lung Arising from a Cornual Pregnancy

Chung DY, Yeo HM, Lee ES, Lee NW, Kim T, Kim HJ, Kim SH, Lee KW

  • KMID: 2272721
  • Korean J Obstet Gynecol.
  • 2005 Oct;48(10):2474-2478.
Gestational trophoblastic disease is derived from the intermediate trophoblast cells which are arisied from the fetal chorion. The incidence of invasive mole in Korea was about 1.8 per 1000 delivereies....
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Clinical Significance of the Placental Proteins (p-hCG, SP1, PP10) in Trophoblastic Disease

Jung JK, Kim JW, Bae SN, Song SK, Han KT, Lee HY

  • KMID: 2083710
  • Korean J Gynecol Oncol Colposc.
  • 1992 Mar;3(1):61-71.
In order to find out whether the serum levels of three placental proteins, human chorionic gonsrtotrpin B-suhunit(B-hCG), Schwangershafts Protein l(SP1) and placental protein l0(PP10), can be uaed for prediction of...
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Ultrasonographic analysis of trophoblastic disease

Lee JK, Jo IS, Jung WY, Lee JY, Choi HY, Kim BK

The authors analyzed ultrasonographic findings of 112 cases of trophoblastic disases which were confirmed byD&E or hysterectomy at Wallace Memorial Baptist Hospital from September 1980 to December 1984. The results...
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The Overxpression of p53 in gestational Trophoblastic Disease and Normal Human Placenta

Whang SO, Kim JH, Huh J, Kim YM, Kim YT, Nam JH, Mok JE

  • KMID: 1928749
  • Korean J Gynecol Oncol Colposc.
  • 1997 Sep;8(3):300-314.
Mutations in the tumor suppressor p53 gene are the most frequently observed genetic lesions in human cancers. It seems that wild type p53 does significant role on growth and differentiation...
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The Expression of bcl-2 protein in Gestational Trophoblastic Disease and Chorionic Villi

Kim YT, Huh JR, Kim JH, Na JH, Teon KS, Kong HS, Kim YM, Nam CH, Mok JE

  • KMID: 2261165
  • Korean J Obstet Gynecol.
  • 1998 Sep;41(9):2386-2393.
Bcl-2 is a proto-oncogene that inhibits apoptosis induced by hormones and cytokines and thus extends cell survival, exposing the cell to oncogenic stimuli. It is expressed in various normal tissues...
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Expression of cyclin E in gestational trophoblastic disease

Yi JW, Kim YT, Kim JW, Kim SH, Kim DK

  • KMID: 2143479
  • Korean J Gynecol Oncol Colposc.
  • 2002 Mar;13(1):38-48.
Gestational trophoblastic disease represents a spectrum of lesions characterized by an abnormal proliferation of trophoblast, including partial mole, complete mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor, which have...
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Choriocarcinoma in the Pulmonary Artery Diagnosed and Treated by Emergency Pulmonary Embolectomy

Jo BG, Kim JI, Lee HY, Park SD, Kim SM, Kim YO

  • KMID: 1916101
  • Korean J Thorac Cardiovasc Surg.
  • 2003 Jul;36(7):531-534.
A 43-year-old woman who had had an invasive mole 5 years previously required emergent pulmonary embolectomy under cardiopulmonary bypass. Curative resection was impossible because the tumor invaded the right main...
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MR Imaging of Gestational Trophoblastic Tumor: Role of Gadolinium Enhancement

Choi SY, Byun JY, Kim BS, Yun YH, Mun KM, Park KS, Kim BK, Bae SN, Shinn KS

  • KMID: 2103035
  • J Korean Radiol Soc.
  • 1997 Dec;37(6):1097-1104.
PURPOSE: To investigate the role of gadolinium enhanced MR imaging in the evaluation of gestational trophoblastic tumors (invasive mole and choriocarcinoma). MATERIALS AND METHODS: Pre-enhanced T1-and T2-weighted images and gadolinium...
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Malignant gestational trophobalstic tumor with markedly elevated serum hCG levels and negative urine hCG level

Kim HS, Choi JH, Park YK, Beon JH, Kim YO, Kim DJ, Choi B, Cho S

  • KMID: 2273184
  • Korean J Obstet Gynecol.
  • 2007 Sep;50(9):1277-1283.
Gestational trophoblastic disease comprises a spectrum of interrelated conditions originating from the placenta. Malignant gestational trophoblastic disease refers to lesions that have the potential for local invasion and metastasis. This...
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Bullae-Forming Pulmonary Metastasis from Choriocarcinoma Presenting as Pneumothorax

Hyun K, Jeon HW, Kim KS, Choi KB, Park JK, Park HJ, Wang YP

Gestational trophoblastic disease (GTD) is a condition of uncertain etiology, choriocarcioma, or placental-site hydatidiform moles, invasive moles, choriocarcinoma, and placental-site trophoblastic tumors. It arises from the abnormal proliferation of trophoblastic...
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MR Imaging of Gestational Trophoblastic Tumors

Kim HH, Lee JH, Song HH, Lee EJ, Kim TG, Park JB, Ha HK, Ro SC, Jee MK, Chung JG

  • KMID: 2102391
  • J Korean Radiol Soc.
  • 1994 Sep;31(3):529-534.
PURPOSE: To evaluate the MR findings of gestational trophoblastic tumor(GTT) in correlation with pathological results. MATERIALS AND METHODS: Nine patients who confirmed the diagnosis (four choriocarcinomas and five invasive moles) constituted the...
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