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In Vitro Culture of Endothelial Cell and Smooth Muscle Cell for Studying Vascular Diseases

Kim JY

Endothelial cells play a key role in pathological processes such as cancer cell metastasis, atherosclerosis, and diabetic retinopathy. Vascular smooth muscle cells directly involve in the formation of atheroma in...
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Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis

Park JH, Park GM, Kim JK

Here, we investigated the role of zerumbone, a natural cyclic sesquiterpene of Zingiber zerumbet Smith, on angiogenesis using human umbilical vein endothelial cells (HUVECs). Zerumbone inhibited HUVECs proliferation, migration and...
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Apoptotic Effect of Radiocontrast Media on Human Umbilical Vein Endothelial Cells

Lee S, Kim SK, Jung SJ, Lee SY, Sung MJ, Moon SO, Kim W, Park SK

  • KMID: 2204431
  • J Korean Soc Vasc Surg.
  • 2004 May;20(1):30-38.
The damage of vascular endothelial cells leads to the progression of vascular disease. Apoptotic damage of endothelial cells is an important mechanism in vascular disease. Recently, it has been reported...
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The Effect of Erythropoietin on the Production of Endothelin in Human Glomerular and Umbilical Endothelial Cells

Park SK, Kim SW, Yang WS, Kim CS, Ahn HJ, Park JS, Lee JD

  • KMID: 2254963
  • Korean J Nephrol.
  • 1998 May;17(3):383-390.
The administration of erythropoietin for renal failure patients is frequently associated with a mild-to-marked rise in arterial blood pressure. The erythropoietin-induced hypertension has been variably attributed to the rise in...
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Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells

Ahn HY, Kim CH

Inducible nitric oxide synthase (iNOS) is a main enzyme producing nitric oxide during inflammation and thus contributes to the initiation and development of inflammatory cardiovascular diseases such as atherosclerosis. Epigallocatechin-3-gallate...
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The effect of the sera from severe preeclamptic patients on endothelial cell viability and endothelin-1 in cultured human umbilical vein endothelial cells

Kim YY, Na WY, Lee JK, Lee Y, Baik EJ, Rha JG, Kim SJ, Lee HG, Shin JC, Kim SP

  • KMID: 2262033
  • Korean J Obstet Gynecol.
  • 2000 Jul;43(7):1162-1167.
OBJECTIVES: In order to assess the effects of sera from severe preeclamptic patients on endothelial cell viability in vitro and endothelin-1 synthesis in cultured human umbilical vein endothelial cells. METHODS: The cultured...
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Platelets Induce Proliferation of Human Umbilical Vein Endothelial Cells via CD154-CD40 Pathway Independently of VEGF

Cho W, Ko EM, Cheon IS, Jeoung DI, Kim YM, Choe J

BACKGROUND: Platelets take part in repairing the lesions of endothelial damage. To understand the molecular mechanism of this process, we tested the hypothesis that CD154 expressed on activated platelets stimulates...
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Inhibitory Effects of CD99-derived Peptide CD99CRIII3 on the Extravasation of Monocytes and Inflammatory Reactions in Contact Dermatitis Mouse Model

Ju HM, Park KH

Leucocyte extravasation has been known to play an important role in inflammatory reactions including contact dermatitis. Previous studies suggested that CD99 regulates β1 integrin activity and may be a novel...
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Effects of Low Intensity Ultrasound on the Co-Culture of Human Osteoblastic Cells (SaOS-2) with Endothelial Cells (HUVEC)

Choo SK, Kim BJ

  • KMID: 2104902
  • J Korean Orthop Res Soc.
  • 2002 Oct;5(2):140-150.
PURPOSE: We investigated the effects of low intensity ultrasound on the co-culture of human osteoblastic cells with endothelial cells and analysed cell proliferation and growth factors that might be involved...
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The Effect of VEGF (Vascular endothelial growth factor) on Endothelial Cells in Pathogenesis of Preeclampsia

Cho YK, Lee HK

  • KMID: 1925520
  • Korean J Obstet Gynecol.
  • 2002 Aug;45(8):1354-1359.
OBJECTIVE: Preeclampsia is primarily a disorder of the maternal endothelium. The objective of this study was to assess the effect of VEGF on human umbilical vein endothelial cells (HUVEC) in...
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Effect of Plasma from Preeclamptic Women on the Nitric Oxide Production in Cultured Human Umbilical Vein Endothelial Cells

Kim A, Lee PY, Jung BG, Yoo HK, Won HS, Lee IS, Nam CH

  • KMID: 2269600
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):990-996.
OBJECTIVE: To evaluate whether preeclamptic plasma changes nitric oxide[NO] production in cultured human umbilical vein endothelial cells. MATERIALS AND METHODS: Plasma were collected from 10 severe preeclamptic women and 10...
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ICAM-1 and VCAM-1 on Human Umbilical Vein Endothelial Cells Infected by Hantaan Virus

Seol MJ, Kang ET, Lee TW, Kim CH, Choi JY, Yoo SJ, Oh DJ, Yu SH

  • KMID: 1889319
  • Korean J Nephrol.
  • 2002 Sep;21(5):706-712.
PURPOSE: Hemorrhagic fever with renal syndrome (HFRS) is an acute febrile disease caused by Hantaan virus. It is believed that various kinds of inflammatory mediators and cytokines might be involved...
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Increased expression of adhesion molecules on human umbilical vein endothelial cells by Orientia tsutsugamushi infection

Lee EB, Han SH, Kim SW, Ihn KS, Seong SY, Kim IS, Choi MS

  • KMID: 2146889
  • J Korean Soc Microbiol.
  • 2000 Apr;35(2):159-169.
Scrub typhus is caused by Orientia tsutsugamushi characterized by fever, headache, lymphadenopathy and eschar formation. Infiltration of inflammatory cells around blood vessels and within the affected organs is known to be pathologic hallmark...
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Hantaan Virus Reduces the von Willebrand Factor in Human Umbilical Vein Endothelial Cells

Cho MR, Hwang JY, Park HS

To understand the molecular mechanism of hemorrhagic tendency represented in hemorrhagic fever with renal syndrome (HFRS), the effect of Hantaan virus (HTNV) on the von Willebrand factor (vWF) was observed...
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Effects of magnesium sulfate on VEGF and Caspase-3 of HUVECs (Human umbilical vein endothelial cells)

Lee GS, Kim SJ, Kim SY, Lee Y, Park SH, Shin JC, Lew YO, Kim SP

  • KMID: 2072174
  • Korean J Perinatol.
  • 2004 Sep;15(3):262-267.
OBJECTIVES: To determine the effects of magnesium sulfate on Caspase-3 and Vascular endothelial growth factor (VEGF) of human umbilical vein endothelial cells (HUVECs) under presence or absence of Tumor necrosis...
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The Anti-apoptotic Effect of Adrenomedullin on Vascular Endothelial Cells in Radiocontrast Media-induced Apoptosis

Kang KP, Lee AS, Jung YJ, Kim DH, Ko KS, Choi KH, Jeong YW, Lee S, Park SK, Sung MJ, Kim W

  • KMID: 2253610
  • Korean J Nephrol.
  • 2008 Jan;27(1):4-12.
PURPOSE: Because vascular endothelial cells play a pivotal role in the vascular diseases, damage of vascular endothelial cells lead to progression of vascular disease. Apoptotic damage of cells is an...
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Propofol attenuates hydrogenperoxide-induced apoptosis in human umbilical vein endothelial cells via multiple signaling pathways

Xie CL, Pan YB, Hu LQ, Qian YN

BACKGROUND: Propofol has been reported to protect vascular endothelial cells against oxidative stress. In this study we investigated its effect on hydrogen peroxide (H2O2)-induced apoptosis of human umbilical vein endothelial...
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Epigallocatechin-3-gallate Regulates NADPH Oxidase Expression in Human Umbilical Vein Endothelial Cells

Ahn HY, Kim CH, Ha TS

Vascular NADPH oxidase plays a pivotal role in producing superoxide in endothelial cells and thus acts in the initiation and development of inflammatory cardiovascular diseases such as atherosclerosis. Epigallocatechin-3-gallate (EGCG),...
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Ex vivo Expansion of Hematopoietic Progenitor Cells in Co-culture of Cord Blood CD34+Cells with Human Umbilical Vein Endothelial Cells

Hwang JH, Kim SW, Chun JM, Park NS, Park SE, Park SJ, Yun HJ, Jo DY, Kim S

  • KMID: 1637338
  • Korean J Hematol.
  • 2004 Sep;39(3):149-157.
BACKGROUND: We examined an ex vivo expansion system for cord blood (CB) hematopoietic progenitor cells, which is based upon a co-culture of CD34+cells with human umbilical endothelial cells (HUVECs) in...
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The Effects of Intravenous Immunoglobulin(IVIG) and Methylprednisolone on the mRNAs Expressions of VEGF, VCAM-1 and IL-1beta of Human Umbilical Vein Endothelial Cells(HUVEC) Stimulated by IL-1beta

Kim SY, Lim SJ, Han JW, Lee KY, Lee JS

  • KMID: 2279493
  • Korean J Pediatr.
  • 2004 Dec;47(12):1325-1333.
PURPOSE: Kawasaki disease(KD) manifests a systemic vasculitis of unknown etiology in young children. Vascular endothelial growth factor(VEGF), vascular cell adhesion molecule-1(VCAM-1) and interleukin-1 beta(IL-1beta) may play important roles in the...
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