- Role of GTP - binding Protein in Signal Transduction
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Cha BY
- KMID: 2461507
- J Korean Soc Endocrinol.
- 1994 Sep;9(3):163-179.
No abstract available. -
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- Nucleoside Diphosphate Kinase from Microorganisms
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Choi CH
- KMID: 2168678
- J Bacteriol Virol.
- 2013 Jun;43(2):92-98.
- doi: 10.4167/jbv.2013.43.2.92
Nucleoside diphosphate kinase (Ndk) is ubiquitous and highly conserved multifunctional key enzyme in nucleotide metabolism. It generates nucleoside triphosphates (NTPs) by transfer of gamma-phosphates from nucleoside triphosphates such as ATP... -
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- The Protective Effect of Mannitol and Methylprednisolone in the Acute Focal Cerebral Ischemia in Cats
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Shin KM
- KMID: 2170822
- Ewha Med J.
- 1988 Dec;11(4):283-297.
- doi: 10.12771/emj.1988.11.4.283
It is the purpose of the this experimental study to investigate the protective effect of pretreatment of mannitol and methylprednisolone(MP) on the changes of the high-energy metabolites(nucleotides ; derivatives of... -
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- An Experimental Study of the Biochemical Alterations in the Acute Focal Cerebral Ischemia:Disturbance of Energy Metabolism
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Sheen YC, Shin KM
- KMID: 2187657
- J Korean Neurosurg Soc.
- 1989 Apr;18(4):525-533.
The energy metabolism of the brain has been measured in cat model using high performance liquid chromatography(HPLC). The experimental groups were divided into three according to the duration of ischemia.... -
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- A Case of Hyperinsulinism/hyperammonemia Syndrome
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Sung JY, Hong SY, Shin CH, Yang SW
- KMID: 1838802
- J Korean Soc Pediatr Endocrinol.
- 2005 Dec;10(2):236-240.
The hyperinsulinism/hyperammonemia (HI/HA) syndrome is a form of congenital hyperinsulinism. The children with HI/HA syndrome present recurrent symptomatic hypoglycemia and asymptomatic, persistent hyperammonemia, caused by mutations of the GLUD1 encoding... -
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- The Combined Therapeutic Effect of Drugs in Experimental Acute Focal Cerebral Ischemia
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Yoo DJ, Shin KM, Han JS
- KMID: 1673474
- J Korean Neurosurg Soc.
- 1990 Feb;19(2):217-224.
The study was designed to examine the effects of pretreatment with mannitol, methyl prednisolone and nimodipine on the acute focal cerebral ischemia in the cats of occlusion of the proximal... -
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- An Experiments Study of the Effect of Ischemic Edema on Cerebral Energy Metabolism
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Jang IT, Shin KM
- KMID: 2068310
- J Korean Neurosurg Soc.
- 1987 Mar;16(1):235-246.
The author studied the effect of the recirculation on the energy metabolism in acute focal cerebral ischemia. Acute focal cerebral ischemia was produced by transorbital occlusion of the left middle... -
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- Isolation of GTP binding from bovine brain
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Kim JH
- KMID: 2320404
- Yeungnam Univ J Med.
- 1993 Dec;10(2):360-368.
GTP binding protein (G-protein) associated with membrane and involved in signal transduction was isolated from bovine brain, and molecular weight of G protein was observed. As the results, cell membranes were... -
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- Effects of Uridine 5'-Triphosphate on the Vascular Tone of Rat Thoracic Aorta
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Park KS, Kong ID, Lee JW
- KMID: 2228958
- Korean Circ J.
- 1995 Feb;25(1):68-77.
- doi: 10.4070/kcj.1995.25.1.68
BACKGROUND: Uracil nucleotides are stored in platelets and all other cells, and are released into the extracellular space upon stimulation. They show various biological responses but their actions and mechanism... -
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- Effect of ATP on Calcium Channel Modulation in Rat Adrenal Chromaffin Cells
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Kim KA, Goo YS
- KMID: 1910548
- Prog Med Phys.
- 2014 Sep;25(3):157-166.
- doi: 10.14316/pmp.2014.25.3.157
ATP in quantity co-stored with neurotransmitters in the secretory vesicles of neurons, by being co-released with the neurotransmitters, takes an important role to modulate the stimulus-secretion response of neurotransmitters. Here,... -
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- Experimental Study of the Protection Against the Acute Focal Cerebral Ischemia
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Shim KM
- KMID: 2170834
- Ewha Med J.
- 1989 Mar;12(1):33-44.
- doi: 10.12771/emj.1989.12.1.33
The purpose of this experimental study is to determine the protective effect of pretreatment of mannitol, methylprednisolone, thiopental sodium and nimodipine against the acute focal cerebral ischemia. The energy metabolisms... -
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- A Case of Dopa-responsive Dystonia with a Mutation in the GCH1 Gene Misdiagnosed as Cerebral Palsy for 2 Years
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Yi CH, Yang HJ, Kim HJ, Lee KY
- KMID: 2435273
- J Korean Child Neurol Soc.
- 2018 Mar;26(1):43-47.
- doi: 10.26815/jkcns.2018.26.1.43
Dopa-responsive dystonia (DRD) is characterized by lower limb-onset, diurnally fluctuating dystonia and dramatic and sustained response to levodopa treatment. Segawa disease, an autosomal dominant deficiency of guanosine triphosphate cyclohydrolase 1... -
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- Mycophenolic Acid Induced Apoptotic Signal Transduction in Molt-4 T-cells
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Choi SJ, Chung SY, Kim SK
- KMID: 2004711
- J Korean Surg Soc.
- 2002 Jan;62(1):8-17.
PURPOSE: Mycophenolic acid (MPA), a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH), is the active metabolite of the immunosuppressive drug, mycophenolate mofetil (MMF). MMF is used to prevent an immune-... -
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- Polymorphisms in RAS Guanyl-releasing Protein 3 are Associated with Chronic Liver Disease and Hepatocellular Carcinoma in a Korean Population
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Oh AR, Lee SK, Kim MH, Cheong JY, Cho SW, Yang KS, Kwack K
- KMID: 2166418
- Genomics Inform.
- 2008 Dec;6(4):181-191.
RAS guanyl-releasing protein 3 (RasGRP3), a member of the Ras subfamily of GTPases, functions as a guanosine triphosphate (GTP)/guanosine diphosphate (GDP)-regulated switch that cycles between inactive GDP- and active GTP-bound... -
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- Analysis of nucleotides and their derivatives in renal tissue of rat during ischemia by HPLC
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Kim SY, Kim JH
- KMID: 2377607
- Yeungnam Univ J Med.
- 1992 Jun;9(1):90-101.
- doi: 10.12701/yujm.1992.9.1.90
In rat kidney, the changes in concentrations of nucleotides and their derivatives during ischemia induced by renal artery ligation was measured quantitatively with high performance liquid chromatography (HPLC). After the ligation... -
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- Levels of Urinary Neopterin in Patients with Lepromatous Leprosy and Patients with Erythema Nodosum Leprosum
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Kim BC, Lee KS, Song JY, Kwak CS
- KMID: 2231319
- Korean J Dermatol.
- 1988 Jun;26(3):306-313.
In lepromatous leprosy, it is generally believed that there is not only defective CMl specific for M. leprae, but also generalized impairment of CMI and in erythema nodosum leprosum, an... -
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- Forskolin Changes the Relationship between Cytosolic Ca2+ and Contraction in Guinea Pig Ileum
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Han KH, Cheon GJ, Yeon DS, Kwon SC
- KMID: 2071670
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):189-194.
- doi: 10.4196/kjpp.2009.13.3.189
This study was designed to clarify the mechanism of the inhibitory effect of forskolin on contraction, cytosolic Ca2+ level ([Ca2+]i), and Ca2+ sensitivity in guinea pig ileum. Forskolin (0.1 nM~10... -
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- Mizoribine-mediated Apoptosis Signaling in Jurkat T Cells
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Seo KW, Chung SH, Chung SY, Kim SK, Choi SN
- KMID: 1896293
- J Korean Surg Soc.
- 2004 Apr;66(4):259-270.
PURPOSE: Mizoribine (MZR), an inhibitor of Inosine monophosphate (IMP) dehydrogenase which depletes cellular GTP, is clinically used as an immunosuppressive drug. This study was designed to evaluate the mechanism by... -
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- Differences in Clinical Laboratory Data between the Elderly and the Young Adults
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Lee KA, Lee KM, Jung SP, Bae SW
- KMID: 2320339
- Yeungnam Univ J Med.
- 1997 Dec;14(2):430-442.
Due to the lowering of biological functions resulted from old age, the elderly is known to have many different clinical laboratory data compared with the young adults. But, in korea,... -
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- A Case of progressive elevation of serum gamma-GTP level in ataxia-telangiectasia
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Song MH, Kim EJ, Sung TJ, Shin SH, Lee KH, Kim HD
- KMID: 2329594
- J Korean Child Neurol Soc.
- 2006 Nov;14(2):363-368.
Ataxia-telangiectasia is an autosomal recessive disorders characterized by cerebellar ataxis, oculocutaneous telangiectasia and frequent respiratory infections due to immunoincompetence. Ataxia usually appear by age of 2 years with most patients... -
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