- A New Perspective on the Heterogeneity of Cancer Glycolysis
-
Neugent ML, Goodwin J, Sankaranarayanan I, Yetkin CE, Hsieh MH, Kim JW
- KMID: 2400810
- Biomol Ther.
- 2018 Jan;26(1):10-18.
- doi: 10.4062/biomolther.2017.210
Tumors are dynamic metabolic systems which highly augmented metabolic fluxes and nutrient needs to support cellular proliferation and physiological function. For many years, a central hallmark of tumor metabolism has... -
- CITED
-
- Close
- SHARE
-
- Close
- Imaging of Cancer Metabolism using Positron Emission Tomography
-
Yun MJ, Lee JD
- KMID: 1469545
- J Korean Med Assoc.
- 2009 Feb;52(2):113-120.
- doi: 10.5124/jkma.2009.52.2.113
In the 1920's, Warburg reported an observation that cancer cells depend on glycolysis even in the presence of available oxygen likely due to impaired function of mitochondria. Since then, this... -
- CITED
-
- Close
- SHARE
-
- Close
- c-Myc-Induced Long Non-Coding RNA Small Nucleolar RNA Host Gene 7 Regulates Glycolysis in Breast Cancer
-
Zhang L, Fu Y, Guo H
- KMID: 2470891
- J Breast Cancer.
- 2019 Dec;22(4):533-547.
- doi: 10.4048/jbc.2019.22.e54
PURPOSE: Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported... -
- CITED
-
- Close
- SHARE
-
- Close
- Glycolysis and the Hexosamine Biosynthetic Pathway as Novel Targets for Upper and Lower Airway Inflammation
-
Kim YH, Nakayama T, Nayak J
- KMID: 2428844
- Allergy Asthma Immunol Res.
- 2018 Jan;10(1):6-11.
- doi: 10.4168/aair.2018.10.1.6
Glycolysis is a process that rapidly converts glucose to lactate to produce adenosine triphosphate (ATP) under anaerobic conditions and occurs in all eukaryotic and prokaryotic cells. On the other hand,... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes of Various Epidermal Enzymatic Activities of Diabetic patients
-
Lee SH, Lee HS, Choi EH, Im MJ
- KMID: 2230812
- Korean J Dermatol.
- 1994 Apr;32(2):217-222.
BACKGROUND: In our previous report, we observed the increaseed epidermal glucose concentrations and decreased hexokinase actiuities of diabetic patients which were ciimpared to those of normal individuals. And we considered... -
- CITED
-
- Close
- SHARE
-
- Close
- Cancer cell metabolism: implications for therapeutic targets
-
Jang M, Kim SS, Lee J
- KMID: 2154264
- Exp Mol Med.
- 2013 Oct;45(10):e45.
Cancer cell metabolism is characterized by an enhanced uptake and utilization of glucose, a phenomenon known as the Warburg effect. The persistent activation of aerobic glycolysis in cancer cells can... -
- CITED
-
- Close
- SHARE
-
- Close
- Oncogene-Driven Metabolic Alterations in Cancer
-
Min HY, Lee HY
- KMID: 2400814
- Biomol Ther.
- 2018 Jan;26(1):45-56.
- doi: 10.4062/biomolther.2017.211
Cancer is the leading cause of human deaths worldwide. Understanding the biology underlying the evolution of cancer is important for reducing the economic and social burden of cancer. In addition... -
- CITED
-
- Close
- SHARE
-
- Close
- Evolution of Energy Metabolism, Stem Cells and Cancer Stem Cells: How the Warburg and Barker Hypotheses Might Be Linked
-
Trosko JE, Kang KS
- KMID: 1426156
- Int J Stem Cells.
- 2012 May;5(1):39-56.
The evolutionary transition from single cells to the metazoan forced the appearance of adult stem cells and a hypoxic niche, when oxygenation of the environment forced the appearance of oxidative... -
- CITED
-
- Close
- SHARE
-
- Close
- Regulation of glucose metabolism from a liver-centric perspective
-
Han HS, Kang G, Kim JS, Choi BH, Koo SH
- KMID: 2361505
- Exp Mol Med.
- 2016 Mar;48(3):e218.
- doi: 10.1038/emm.2015.122
Glucose homeostasis is tightly regulated to meet the energy requirements of the vital organs and maintain an individual's health. The liver has a major role in the control of glucose... -
- CITED
-
- Close
- SHARE
-
- Close
- Histone Deacetylase-3 Modification of MicroRNA-31 Promotes Cell Proliferation and Aerobic Glycolysis in Breast Cancer and Is Predictive of Poor Prognosis
-
Zhao Y, He J, Yang L, Luo Q, Liu Z
- KMID: 2413929
- J Breast Cancer.
- 2018 Jun;21(2):112-123.
- doi: 10.4048/jbc.2018.21.2.112
PURPOSE: The incidence and mortality of breast cancer is increasing worldwide. There is a constant quest to understand the underlying molecular biology of breast cancer so as to plan better... -
- CITED
-
- Close
- SHARE
-
- Close
- Prognostic Significance of Volume-Based PET Parameters in Cancer Patients
-
Moon SH, Hyun SH, Choi JY
- KMID: 1430038
- Korean J Radiol.
- 2013 Feb;14(1):1-12.
- doi: 10.3348/kjr.2013.14.1.1
Accurate prediction of cancer prognosis before the start of treatment is important since these predictions often affect the choice of treatment. Prognosis is usually based on anatomical staging and other... -
- CITED
-
- Close
- SHARE
-
- Close
- Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation
-
Aldonza MB, Hong JY, Lee SK
- KMID: 2367532
- Exp Mol Med.
- 2017 Jan;49(1):e286.
- doi: 10.1038/emm.2016.131
Chemotherapy-induced cancer cell secretomes promote resistance due, in part, to a predominant glycolytic energy metabolism, which drives aggressive cancer cell proliferation. However, the characterization of these secretomes and the molecular... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Adult Onset Glycogen Storage Myopathy
-
Shin JH, Kim DG, Shin JY, Park SH, Lee KW
- KMID: 1737970
- Korean J Clin Neurophysiol.
- 2014 Dec;16(2):81-85.
- doi: 10.14253/kjcn.2014.16.2.81
Primary metabolic myopathy as a type of congenital myopathies was first described by McArdle in 1951. Glycogen storage disease is a disease caused by genetic mutations involved in glycogen synthesis,... -
- CITED
-
- Close
- SHARE
-
- Close
- Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas
-
Jha MK, Suk K
- KMID: 2048476
- Brain Tumor Res Treat.
- 2013 Oct;1(2):57-63.
- doi: 10.14791/btrt.2013.1.2.57
Metabolic aberrations in the form of altered flux through key metabolic pathways are the major hallmarks of several life-threatening malignancies including malignant gliomas. These adaptations play an important role in... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Arterial Hypoxemia on Cerebral Blood Flow and Metabolism
-
Kwak IY
- KMID: 2357409
- Korean J Anesthesiol.
- 1981 Mar;14(1):26-30.
In anesthetized normocapnic and normotensive dogs, the effect of arterial hypoxemia on cerebral blood flow and oxidative carbohydrate metabolism was studied. The results are as follows: 1) The hypoxic vasodilatory... -
- CITED
-
- Close
- SHARE
-
- Close
- Epidermal glucoss content and hexokinase activities of diabetic patients with xerosis
-
Kim DK, Lee ES, Im JC
- KMID: 2038893
- Korean J Dermatol.
- 1993 Feb;31(1):65-71.
It is well estabilshed that the xerosis is closely related to diabeic pruritus. Although the causes of xerosis are thought to bie the abnormalities of sweating and autonomic nervous system,... -
- CITED
-
- Close
- SHARE
-
- Close
- Imaging of Gastric Cancer Metabolism Using 18 F-FDG PET/CT
-
Yun M
- KMID: 2372017
- J Gastric Cancer.
- 2014 Mar;14(1):1-6.
Aerobic glycolysis has been the most important hypothesis in cancer metabolism. It seems to be related to increased bioenergetic and biosynthetic needs in rapidly proliferating cancer cells. To this end,... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Glycolysis-Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status
-
Kwon JE, Jung WH, Koo JS
- KMID: 2068665
- Yonsei Med J.
- 2014 May;55(3):576-583.
- doi: 10.3349/ymj.2014.55.3.576
PURPOSE: The aim of this study was to investigate the differences of expression in glycolysis-related proteins such as Glut-1, carbonic anhydrase (CA) IX, and monocarboxylate transporter (MCT) 4 according to... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Exercise Training on Insulin Sensitivity and Intracellular Glucose Metabolism in Skeletal Muscle of High Fat-fed Rats
-
Kim CH, Park JY, Hong SK, Park KS, Lee HK, Lee KU
- KMID: 2178017
- J Korean Diabetes Assoc.
- 1998 Jun;22(2):231-242.
BACKGROUND: Insulin resistance is a major characteristic of non-insulin-dependent diabetes mellitus and obesity. Many studies have indicated that increased intake of fat are associated with obesity and insulin resistance. On... -
- CITED
-
- Close
- SHARE
-
- Close
- Mechanisms of Glucose Uptake in Cancer Tissue
-
Chung JK
- KMID: 1556298
- Korean J Nucl Med.
- 1999 Feb;33(1):1-10.
Cancer cells are known to show increased rates of glycolysis metabolism. Based on this, PET studies using F-18-fluorodeoxyglucose have been used for the detection of primary and metastatic tumors. To... -
- CITED
-
- Close
- SHARE
-
- Close
