- Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes
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Hewage SR, Piao MJ, Kang KA, Ryu YS, Fernando P, Oh MC, Park JE, Shilnikova K, Moon YJ, Shin DO, Hyun JW
- KMID: 2386910
- Biomol Ther.
- 2017 Jul;25(4):427-433.
- doi: 10.4062/biomolther.2016.112
Previously, we demonstrated that galangin (3,5,7-trihydroxyflavone) protects human keratinocytes against ultraviolet B (UVB)-induced oxidative damage. In this study, we investigated the effect of galangin on induction of antioxidant enzymes involved... -
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- Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine on Glutathione Homeostasis in Ethanol-induced Acute Hepatotoxicity
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Lee SY, Ko KS
- KMID: 2367574
- J Cancer Prev.
- 2016 Sep;21(3):164-172.
- doi: 10.15430/JCP.2016.21.3.164
BACKGROUND: Exposure to ethanol abuse and severe oxidative stress are risk factors for hepatocarcinoma. The aim of this study was to evaluate the effects of S-adenosylmethionine (SAMe) and its combinations... -
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- Schisandra Chinensis Baillon regulates the gene expression of phase II antioxidant/detoxifying enzymes in hepatic damage induced rats
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Jang HI, Do GM, Lee HM, Ok HM, Shin JH, Kwon O
- KMID: 2313739
- Nutr Res Pract.
- 2014 Jun;8(3):272-277.
BACKGROUND/OBJECTIVES: This study investigated the antioxidant activities and hepatoprotective effects of Schisandra chinensis Baillon extract (SCE) against tert-butyl hydroperoxide (t-BHP)-induced oxidative hepatic damage in rats. MATERIALS/METHODS: Sprague-Dawley (SD) rats were pretreated... -
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- Modulated Gene Expression of Toxoplasma gondii Infected Retinal Pigment Epithelial Cell Line (ARPE-19) via PI3K/Akt or mTOR Signal Pathway
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Zhou W, Quan JH, Gao FF, Ismail HA, Lee YH, Cha GH
- KMID: 2412732
- Korean J Parasitol.
- 2018 Apr;56(2):135-145.
- doi: 10.3347/kjp.2018.56.2.135
Due to the critical location and physiological activities of the retinal pigment epithelial (RPE) cell, it is constantly subjected to contact with various infectious agents and inflammatory mediators. However, little... -
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- Evaluation of in vitro anti-oxidant and anti-inflammatory activities of Korean and Chinese Lonicera caerulea
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Lee YS, Cho IJ, Kim JW, Lee SK, Ku SK, Lee HJ
- KMID: 2448693
- Nutr Res Pract.
- 2018 Dec;12(6):486-493.
- doi: 10.4162/nrp.2018.12.6.486
BACKGROUND/OBJECTIVES: The honeysuckle berry (HB) contains ascorbic acid and phenolic components, especially anthocyanins, flavonoids, and low-molecular-weight phenolic acids. In order to examine the potential of HB as a hepatoprotective medicinal... -
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