- A Short History of the Genome-Wide Association Study: Where We Were and Where We Are Going
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Ikegawa S
- KMID: 2053300
- Genomics Inform.
- 2012 Dec;10(4):220-225.
- doi: 10.5808/GI.2012.10.4.220
Recent rapid advances in genetic research are ushering us into the genome sequence era, where an individual's genome information is utilized for clinical practice. The most spectacular results of the... -
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- Genome-Wide Association Study of Hepatitis in Korean Populations
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Hong Y, Oh S
- KMID: 2391497
- Genomics Inform.
- 2014 Dec;12(4):203-207.
- doi: 10.5808/GI.2014.12.4.203
Hepatitis is a common and serious disease for the Korean population. It is caused by a virus, the A and B types of which are plentiful in Koreans. In this... -
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- Genome-Wide Association Study in Psychiatric Disorders
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Kim SJ, Hong KS
- KMID: 2341852
- J Korean Neuropsychiatr Assoc.
- 2011 Jan;50(1):20-38.
Most psychiatric disorders are some kinds of complex genetic traits. Identifying the causal genes of psychiatric disorders has been challenging. Through recent revolutionary advances, such as the HapMap Project and... -
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- Response: Genome-Wide Association Study Identifies Two Novel Loci with Sex-Specific Effects for Type 2 Diabetes Mellitus and Glycemic Traits in a Korean Population (Diabetes Metab J 2014;38:375-87)
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Go MJ, Kim BJ
- KMID: 2174088
- Diabetes Metab J.
- 2014 Dec;38(6):487-488.
- doi: 10.4093/dmj.2014.38.6.487
No abstract available. -
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- Letter: Genome-Wide Association Study Identifies Two Novel Loci with Sex-Specific Effects for Type 2 Diabetes Mellitus and Glycemic Traits in a Korean Population (Diabetes Metab J 2014;38:375-87)
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Kwak SH
- KMID: 2174087
- Diabetes Metab J.
- 2014 Dec;38(6):484-486.
- doi: 10.4093/dmj.2014.38.6.484
No abstract available. -
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- Post-GWAS Strategies
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Kim S, Bhak J
- KMID: 1450879
- Genomics Inform.
- 2011 Mar;9(1):1-4.
Genome-wide association (GWA) studies are the method of choice for discovering loci associated with common diseases. More than a thousand GWA studies have reported successful identification of statistically significant association... -
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- Genetic susceptibility factors of rheumatoid arthritis
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Lee HS
- KMID: 2256060
- Korean J Med.
- 2008 Nov;75(5):515-524.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that mainly involves the joints. Although the full etiology remains unclear, both genetic and environmental factors contribute to disease. Recently, genetic studies... -
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- Comparison of Erythrocyte Traits Among European, Japanese and Korean
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Kwon JS, Kim S
- KMID: 2284671
- Genomics Inform.
- 2010 Sep;8(3):159-163.
Erythrocyte traits are heritable and indirect indicators of blood diseases caused by erythrocyte, but their genetic factors are largely unknown. So we performed genome-wide association study in 8,842 Korean individuals... -
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- The Genetic Basis of Panic Disorder
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Na HR, Kang EH, Lee JH, Yu BH
- KMID: 1785953
- J Korean Med Sci.
- 2011 Jun;26(6):701-710.
- doi: 10.3346/jkms.2011.26.6.701
Panic disorder is one of the chronic and disabling anxiety disorders. There has been evidence for either genetic heterogeneity or complex inheritance, with environmental factor interactions and multiple single genes,... -
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- Genome-Wide Association Study of Medication Adherence in Chronic Diseases in the Korean Population
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Seo I, Suh SI, Suh MH, Baek WK
- KMID: 2009099
- Genomics Inform.
- 2014 Sep;12(3):121-126.
- doi: 10.5808/GI.2014.12.3.121
Medication adherence is generally defined as the extent of voluntary cooperation of a patient in taking medicine as prescribed. Adherence to long-term treatment with chronic disease is essential for reducing... -
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- IVAG: An Integrative Visualization Application for Various Types of Genomic Data Based on R-Shiny and the Docker Platform
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Lee TR, Ahn JM, Kim G, Kim S
- KMID: 2404056
- Genomics Inform.
- 2017 Dec;15(4):178-182.
- doi: 10.5808/GI.2017.15.4.178
Next-generation sequencing (NGS) technology has become a trend in the genomics research area. There are many software programs and automated pipelines to analyze NGS data, which can ease the pain... -
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- The Search for Genetic Variants and Epigenetics Related to Asthma
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Lee SH, Park JS, Park CS
- KMID: 2167074
- Allergy Asthma Immunol Res.
- 2011 Oct;3(4):236-244.
- doi: 10.4168/aair.2011.3.4.236
For the past two decades, a huge number of genetic studies have been conducted to identify the genetic variants responsible for asthma risk. Several types of genetic and genomic approaches,... -
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- Genome-wide Association Studies for Osteoporosis: A 2013 Update
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Liu YJ, Zhang L, Papasian C, Deng HW
- KMID: 2241531
- J Bone Metab.
- 2014 May;21(2):99-116.
- doi: 10.11005/jbm.2014.21.2.99
In the past few years, the bone field has witnessed great advances in genome-wide association studies (GWASs) of osteoporosis, with a number of promising genes identified. In particular, meta-analysis of... -
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- Genetic Studies on Diabetic Microvascular Complications: Focusing on Genome-Wide Association Studies
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Kwak SH, Park KS
- KMID: 2282004
- Endocrinol Metab.
- 2015 Jun;30(2):147-158.
- doi: 10.3803/EnM.2015.30.2.147
Diabetes is a common metabolic disorder with a worldwide prevalence of 8.3% and is the leading cause of visual loss, end-stage renal disease and amputation. Recently, genome-wide association studies (GWASs)... -
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- Sulwon Lecture 2009: The Search for Genetic Risk Factors of Type 2 Diabetes Mellitus
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Park KS
- KMID: 2281487
- Diabetes Metab J.
- 2011 Feb;35(1):12-22.
- doi: 10.4093/dmj.2011.35.1.12
Type 2 diabetes mellitus (T2DM) is caused by complex interplay between multiple genetic and environmental factors. The three major approaches used to identify the genetic susceptibility include candidate gene approach,... -
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- Meta-analysis for genome-wide association studies using case-control design: application and practice
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Shim S, Kim J, Jung W, Shin IS, Bae JM
- KMID: 2380748
- Epidemiol Health.
- 2016;38:e2016058.
- doi: 10.4178/epih.e2016058
This review aimed to arrange the process of a systematic review of genome-wide association studies in order to practice and apply a genome-wide meta-analysis (GWMA). The process has a series... -
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- Lessons Learned From GWAS of Asthma
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Kim KW, Ober C
- KMID: 2431850
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):170-187.
- doi: 10.4168/aair.2019.11.2.170
Asthma is a common complex disease of the airways. Genome-wide association studies (GWASs) of asthma have identified many risk alleles and loci that have been replicated in worldwide populations. Although... -
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- Gene Set Analyses of Genome-Wide Association Studies on 49 Quantitative Traits Measured in a Single Genetic Epidemiology Dataset
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Kim J, Kwon JS, Kim S
- KMID: 2009106
- Genomics Inform.
- 2013 Sep;11(3):135-141.
- doi: 10.5808/GI.2013.11.3.135
Gene set analysis is a powerful tool for interpreting a genome-wide association study result and is gaining popularity these days. Comparison of the gene sets obtained for a variety of... -
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- Efficient Strategy to Identify Gene-Gene Interactions and Its Application to Type 2 Diabetes
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Li D, Won S
- KMID: 2366431
- Genomics Inform.
- 2016 Dec;14(4):160-165.
- doi: 10.5808/GI.2016.14.4.160
Over the past decade, the detection of gene-gene interactions has become more and more popular in the field of genome-wide association studies (GWASs). The goal of the GWAS is to... -
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- Genome-Wide Association Study of Metabolic Syndrome in Koreans
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Jeong SW, Chung M, Park SJ, Cho SB, Hong KW
- KMID: 2391495
- Genomics Inform.
- 2014 Dec;12(4):187-194.
- doi: 10.5808/GI.2014.12.4.187
Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we... -
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