- The Effect of Genistein on the Glaucoma Filtering Surgery in Rabbit
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Lee YG, KIm CY, Kim HK, Hong YJ
- KMID: 2124593
- J Korean Ophthalmol Soc.
- 2000 Dec;41(12):2699-2708.
No Abstract Available. -
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- Effect of Genistein on the Survival and Production of Nitric Oxide in Trabecular Meshwork Cells
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Hong JH, Kim YY, Kim JW
- KMID: 2214775
- J Korean Ophthalmol Soc.
- 2011 Aug;52(8):970-974.
- doi: 10.3341/jkos.2011.52.8.970
PURPOSE: To investigate the effects of genistein on the survival and production of nitric oxide in cultured human trabecular meshwork cells (HTMC). METHODS: Primarily cultured HTMC were exposed to 0, 1,... -
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- Bioavailability Assessment of Isoflavones between Soybean and Soybean Sprout in Rat
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Kim EM, Kim KJ, Choi JH, Chee KM
- KMID: 2269837
- Korean J Nutr.
- 2005 Jun;38(5):335-343.
Rodent models have been used to study the anticarcinogenic properties of the soy isoflavones, particularly genistein, but there is little information regarding the pharmacokinetics of the absorption and excretion of... -
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- Effects of genistein on anti-tumor activity of cisplatin in human cervical cancer cell lines
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Liu H, Lee G, Lee JI, Ahn TG, Kim SA
- KMID: 2456827
- Obstet Gynecol Sci.
- 2019 Sep;62(5):322-328.
- doi: 10.5468/ogs.2019.62.5.322
OBJECTIVE: To investigate the effect of genistein on the anticancer effects of chemotherapeutic agents, we examined the effect of a genistein and cisplatin combination on CaSki human cervical cancer cells. METHODS:... -
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- Immunohistochemical Study Of The Vascular Endothelial Growth Factor (Vegf) Expression In Genistein Treated Hamster Buccal Pouch Oral Carcinoma Model
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Myoung H, Kim YY, Choi SM, Chung CP, Kim MJ
- KMID: 1961164
- J Korean Assoc Oral Maxillofac Surg.
- 2002 Apr;28(2):147-154.
Genistein that is a component of soy has been reported to have a protective effect on the carcinogenesis of various tumors and to inhibit the growth of a wide variety... -
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- Effect of Genistein, a Tyrosine Kinase Inhibitor, on the Cloned Rat Brain Potassium Channel Kv1.5
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Choi BH
- KMID: 2071632
- Korean J Physiol Pharmacol.
- 2006 Oct;10(5):243-249.
The effect of genistein, widely used as a specific tyrosine kinase inhibitor, on rat brain Kv1.5 channels which were stably expressed in Chinese hamster ovary cells was investigated using the... -
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- Different Expression of p27(kip1) and p57(kip2) by Genistein Treatment in MDA-MB-231 Human Breast Cancer Cells
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Yoon DS, Song KH, Kim ST
- KMID: 1917896
- J Korean Breast Cancer Soc.
- 2004 Jun;7(2):98-103.
- doi: 10.4048/jkbcs.2004.7.2.98
PURPOSE: The isoflavones in soy are likely to contribute to the historically low incidence of breast cancer among Asian women who consume traditional diets. The possible role of isoflavones in... -
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- Chemopreventive and chemotherapeutic effects of genistein, a soy isoflavone, upon cancer development and progression in preclinical animal models
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Kim SH, Kim CW, Jeon SY, Go RE, Hwang KA, Choi KC
- KMID: 1737415
- Lab Anim Res.
- 2014 Dec;30(4):143-150.
- doi: 10.5625/lar.2014.30.4.143
Genistein is one of isoflavones mostly derived in a leguminous plant. It is well known as one of phytoestrogens that have structures similar to the principal mammalian estrogen. It has... -
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- Genistein improve nicotine toxicity on male mice pancreas
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Salahshoor MR, Mirzaei F, Roshankhah S, Jalili P, Jalili C
- KMID: 2451222
- Anat Cell Biol.
- 2019 Jun;52(2):183-190.
- doi: 10.5115/acb.2019.52.2.183
Nicotine is the most toxic factor of tobacco. Genistein is a phytoestrogen and antioxidant that has numerous health benefits. The aim of this study is to evaluate the effects of... -
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- Genistein-Induced Apoptosis of p815 Mastocytoma Cell
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Song KH, Song KH, Kim KH
- KMID: 2158724
- Ann Dermatol.
- 2002 Jun;14(2):88-97.
- doi: 10.5021/ad.2002.14.2.88
BACKGROUND: Numerous studies demonstrated that genistein induced the decrease of proliferation and apoptosis in a variety of cells. However, there is no report about the effect of genistein on proliferation... -
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- Inhibition of PTK Pa t hway by Genistein in Diabetic Rat
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Kim HC
- KMID: 2108788
- J Korean Ophthalmol Soc.
- 1999 Aug;40(8):2181-2189.
The objective of this study is to determine if the elevated retinal levels of phosphotyrosine in the Zucker diabetic fatty rats can be reduced by systemic administration of genistein,a protein... -
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- Inhibitory Effect of Genistein on the Proliferation of Lens Epithelial Cells
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Byun KD, Yun YS, Oh JH
- KMID: 2125028
- J Korean Ophthalmol Soc.
- 2001 Jun;42(6):877-888.
PURPOSE: The objective of the present studies was to evaluate the effect of genistein on inhibiting growth factor-induced proliferation of lens epithelial cells. METHODS: The effect of genistein on cell... -
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- Absorption Study of Genistein Using Solid Lipid Microparticles and Nanoparticles: Control of Oral Bioavailability by Particle Sizes
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Kim JT, Barua S, Kim H, Hong SC, Yoo SY, Jeon H, Cho Y, Gil S, Oh K, Lee J
- KMID: 2386913
- Biomol Ther.
- 2017 Jul;25(4):452-459.
- doi: 10.4062/biomolther.2017.095
In this study, the effect of particle size of genistein-loaded solid lipid particulate systems on drug dissolution behavior and oral bioavailability was investigated. Genistein-loaded solid lipid microparticles and nanoparticles were... -
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- Effect of genistein administration on the recovery of spermatogenesis in the busulfan-treated rat testis
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Chi H, Chun K, Son H, Kim J, Kim G, Roh S
- KMID: 1493211
- Clin Exp Reprod Med.
- 2013 Jun;40(2):60-66.
- doi: 10.5653/cerm.2013.40.2.60
OBJECTIVE: Impairment of spermatogenesis has been identified as an inevitable side effect of cancer treatment. Although estrogen treatment stimulates spermatogenic recovery from the impaired spermatogenesis by suppressing the intra-testicular testosterone... -
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- Neuroprotective Effect of Genistein Against beta Amyloid-Induced Neurotoxicity
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Bang OY, Mook IH, Huh K
- KMID: 2343041
- J Korean Neurol Assoc.
- 2003 Apr;21(2):174-182.
BACKGROUND: Estrogen is beneficial to patients with Alzheimer's disease but has a limited clinical use due to its proliferative and oncogenic effects on non-neuronal estrogen responsive cells. METHODS: In an... -
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- Preferential Cytotoxic Effect of Genistein on G361 Melanoma Cells Via Inhibition of the Expression of Focal Adhesion Kinase
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Park SR, Kwak HH, Park BS, Kim GC
- KMID: 1431133
- Int J Oral Biol.
- 2012 Dec;37(4):189-195.
Resistance to the induction of apoptosis is a possible mechanism by which tumor cells can survive anti-neoplastic treatments. Melanoma is notoriously resistant to anti-neoplastic therapy. Previous studies have demonstrated focal... -
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- Effects of Genistein Supplementation on Fatty Liver and Lipid Metabolism in Rats Fed High Fat Diet
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Lee SH, Kim MH, Park MN, Lee YS
- KMID: 2260668
- Korean J Nutr.
- 2007 Dec;40(8):693-700.
This study was performed to investigate the effects of genistein, a kind of soy isoflavones, on fatty liver and lipid metabolism in rats fed high fat diet. Twenty four male... -
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- Open Channel Block of Kv3.1 Currents by Genistein, a Tyrosine Kinase Inhibitor
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Choi BH, Park JH, Hahn SJ
- KMID: 2071623
- Korean J Physiol Pharmacol.
- 2006 Apr;10(2):71-77.
The goal of this study was to analyze the effects of genistein, a widely used tyrosine kinase inhibitor, on cloned Shaw-type K+ currents, Kv3.1 which were stably expressed in Chinese... -
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- Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans
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Lee EB, Ahn D, Kim BJ, Lee SY, Seo HW, Cha YS, Jeon H, Eun JS, Cha DS, Kim DK
- KMID: 2380366
- Biomol Ther.
- 2015 Jan;23(1):77-83.
- doi: 10.4062/biomolther.2014.075
The seed of Vigna angularis has long been cultivated as a food or a folk medicine in East Asia. Genistein (4',5,7-trihydroxyisoflavone), a dietary phytoestrogen present in this plant, has been... -
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- Indole-3-carbinol and genistein inhibit growth of human uterine leiomyoma cells
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Jeong HW, Kim YO, Shin SJ, Kwon SH, Cha SD, Cho CH
- KMID: 2077761
- Korean J Obstet Gynecol.
- 2007 Jun;50(6):880-886.
OBJECTIVE: To determine whether Indole-3-carbinol (I3C) can enhance the inhibitory effect of genistein on a human uterine leiomyoma cells. METHODS: Five uterine leiomyoma tissues were obtained from hysterectomies conducted on... -
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