- Down-regulation of Type I Collagen Gene Expression in Human Skin Fibroblasts by G1 Cell Cycle Arrest
-
Park YD, Lee KS
- KMID: 1931117
- Korean J Dermatol.
- 2007 Apr;45(4):362-368.
BACKGROUND: Type I collagen is a major component of extracellular cellular matrix in tissue. It is synthesized by human skin fibroblasts. However, synthesis of type I collagen is markedly-decreased in... -
- CITED
-
- Close
- SHARE
-
- Close
- G1/S Cell Cycle Checkpoint Defect in Lymphocytes from Patients with Alzheimer's Disease
-
Song M, Kwon YA, Lee Y, Kim H, Yun JH, Kim S, Kim DK
- KMID: 2316235
- Psychiatry Investig.
- 2012 Dec;9(4):413-417.
OBJECTIVE: We compared the cell responsiveness of activated lymphocytes to rapamycin, which blocks the G1/S transition, between patients with Alzheimer's disease (AD) and normal controls to assess the early phase... -
- CITED
-
- Close
- SHARE
-
- Close
- The Correlation between the Expression of CD99 and the Cell Cycle
-
Yu CS, Chang MC, Oh SK
- KMID: 2145187
- J Korean Surg Soc.
- 2001 Oct;61(4):347-356.
PURPOSE: The cell cycle control system is necessary for the normal growth and differentiation of cells. The purposes of this study were to compare CD99 expression with a known... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of gamma-radiation on cyclin-dependent kinases and their inhibitors in cultured vascular smooth muscle cells
-
Zo JH
- KMID: 2029537
- Korean Circ J.
- 2001 Jan;31(1):63-73.
- doi: 10.4070/kcj.2001.31.1.63
BACKGROUND: In spite of the clinical introduction of brachytherapy to reduce restenosis, the biologic responses of vascular smooth muscle cells(VSMCs) to radiation have not been well studied. We investigated the... -
- CITED
-
- Close
- SHARE
-
- Close
- Cell Cycle Analysis by Ki-67 Monoclonal Antibody in Acute Myelogenous Leukemia
-
Ahn JS, Kim ES, Kim HT, Park SY, Kim BK
- KMID: 1641956
- Korean J Hematol.
- 2002 Aug;37(3):191-199.
BACKGROUND: Flow cytometric measurement of DNA can reveal G0/G1, S, G2/M phases of cell cycle, and BrdU labeling can determine the percentage of cells in active DNA synthesis. A monoclonal... -
- CITED
-
- Close
- SHARE
-
- Close
- Etoposide-induced Smad6 expression is required for the G1 to S phase transition of the cell cycle in CMT-93 mouse intestinal epithelial cells
-
Lee YS, Lee EK, Han IO, Park SH
- KMID: 1103587
- Exp Mol Med.
- 2008 Feb;40(1):43-51.
- doi: 10.3858/emm.2008.40.1.43
The inhibitory Smad6 and Smad7 are responsible for cross-talk between TGF-beta/bone morphogenic protein (BMP) signaling and other cellular signaling pathways, as well as negative feedback on their own signaling functions.... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of EGFR in Non-small Cell Lung Cancer and its Effects on Survival
-
Kim HR, Jeong ET
- KMID: 2318110
- Tuberc Respir Dis.
- 1997 Dec;44(6):1285-1295.
BACKGROUND: EGFR is one of the initial step in signal transduction pathway about multistep carcinogenesis. It is homologous to oncogene erbB-2 and is the receptor for EGF and TGF alpha.... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of All-trans-retinoic Acid on the Cell Cycle of Head and Neck Squamous Cell Carcinomas
-
Park ST, Lee HS, Yu HK, Kim SY
- KMID: 2274571
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Apr;42(4):471-477.
BACKGROUND AND OBJECTIVE: Retinoids, including vitamin A and its synthetic analogs, are known to suppress carcinogenesis in various epithelial tissues and also to inhibit the cell growth of head and... -
- CITED
-
- Close
- SHARE
-
- Close
- The Changes of Cell Cycle Phase Fractions and Expression of p53 by the Treatment of Staurosporine in MCF-7 Cell Line
-
Nam J, Yea KA, Lee HN, Jo HH, Ryu KS, Lew YO, Rha JG, Han KT
- KMID: 2076195
- Korean J Obstet Gynecol.
- 2001 Mar;44(3):501-505.
OBJECTIVE: We investigated the effects on the cell cycle and p53 expression by the treatment of various concentrations of staurosporine to elucidate the molecular mechanism of staurosporine induced cell cycle... -
- CITED
-
- Close
- SHARE
-
- Close
- Correlation between G1 Cyclins Expression and Clinical Prognostic Parameters in Endometrial Carcinoma
-
Kim YT, Kim SH, Kim JW, Lee JW, Park KH
- KMID: 1615588
- Korean J Gynecol Oncol Colposc.
- 2003 Mar;14(1):30-39.
OBJECTIVE: Cyclins D1 and E play important roles in the progression of cell through G1 phase of the cell cycle. Amplification and/or overexpression of the cyclin D1 gene and aberrant... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Cyclin A and Ki-67 in the Uterine Cervical Carcinoma
-
Kim MK, Bae DH, Kim CJ
- KMID: 2244993
- Korean J Gynecol Oncol Colposc.
- 1998 Dec;9(4):464-470.
The cell cycle is the set of events that is responsible for the duplication of the cells. Recent studies indicate that cell cycle regulatory proteins, mainly the cyclins and cyclin-related... -
- CITED
-
- Close
- SHARE
-
- Close
- The Expression of p53 and p21 in Intradermal Nevus, Junctional Nevus and Malignant Melanoma
-
Song MH, Kim YT, Jang WS, Lee SY, Yang SH, Lee JS, Whang KU, Kim EH
- KMID: 2303110
- Korean J Dermatol.
- 2002 Aug;40(8):869-873.
BACKGROUND: The function of the p53 protein is known to regulate cell proliferation by inhibiting cells entering S phase, so DNA damaged cell proliferation is inhibited by apoptosis. p21 is... -
- CITED
-
- Close
- SHARE
-
- Close
- p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest
-
Chae HD, Kim SY, Park SE, Kim J, Shin DY
- KMID: 1245266
- Exp Mol Med.
- 2012 Mar;44(3):236-240.
- doi: 10.3858/emm.2012.44.3.018
We previously reported that the p53 tumor suppressor protein plays an essential role in the induction of tetraploid G1 arrest in response to perturbation of the actin cytoskeleton, termed actin... -
- CITED
-
- Close
- SHARE
-
- Close
- Ethanol extract of Innotus obliquus (Chaga mushroom) induces G1 cell cycle arrest in HT-29 human colon cancer cells
-
Lee HS, Kim EJ, Kim SH
- KMID: 2313817
- Nutr Res Pract.
- 2015 Apr;9(2):111-116.
- doi: 10.4162/nrp.2015.9.2.111
BACKGROUND/OBJECTIVES: Inonotus obliquus (I. obliquus, Chaga mushroom) has long been used as a folk medicine to treat cancer. In the present study, we examined whether or not ethanol extract of... -
- CITED
-
- Close
- SHARE
-
- Close
- The Change of Molecular Event of p53 by Cisplatin and 5-Fluorouracil in Hypopharyngeal Cell Line(PNUH-12)
-
Chon KM, Lee BJ, Lee IW, Moon YI, Roh HJ, Wang SG, Goh EK, Kim SR, Lee EY
- KMID: 2074461
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Oct;45(10):984-989.
OBJECTIVES AND BACKGROUND: In head and neck cancer including hypopharyngeal carcinoma, cisplatin and 5-fluorouracil usually have been used as neoadjuvant chemotherapeutic agents. We investigated the difference in the influences of... -
- CITED
-
- Close
- SHARE
-
- Close
- The Cell Cycle Dependence and Radiation-induced Apoptosis in SCK Mammary Adenocarcinoma Cell Line
-
Lee HS, Park HK, Hur WJ, Seo SY, Lee SH, Jung MH, Park HJ, Song CW
- KMID: 1840632
- J Korean Soc Ther Radiol Oncol.
- 1998 Jun;16(2):91-98.
PURPOSE: The relationship between environmental pH on the radiation induced-apoptosis in SCK mammary adenocarcinoma cells and cell cycle dependence was investigated. MATERIAL AND METHODS: Mammary adenocarcinoma cells of A/J mice... -
- CITED
-
- Close
- SHARE
-
- Close
- NELL2 gene as regulator of cell cycle in neuron differentiation
-
Joung MR, Oh YM, Park WS, Park SK
- KMID: 2279788
- Korean J Pediatr.
- 2006 Oct;49(10):1100-1105.
- doi: 10.3345/kjp.2006.49.10.1100
PURPOSE: Because NELL2 expression is strictly restricted only in neurons in developing and post- differentiated neural tissues, it is thought to be involved in the neuronal differentiation during development and... -
- CITED
-
- Close
- SHARE
-
- Close
- Induction of apoptosis in human cervical cancer cells by isoliquritizenin
-
Jung SW, Kim YO, Kim SH, Kwon SH, Cho CH, Cha SD
- KMID: 2143526
- Korean J Gynecol Oncol.
- 2006 Mar;17(1):47-53.
OBJECTIVE: Isoliquritizenin (ISL) is a chalcone flavonoid, present in licorice, shallot and bean sprouts, has cancer preventing properties and often used in chinese medicine. In this study, ISL to determine... -
- CITED
-
- Close
- SHARE
-
- Close
- THE ROLE OF REGULATED PROTEINS RELATED TO CELL CYCIE IN CARCINOGENESIS
-
Kwak DH, Lee SH, Kim CH
- KMID: 2190615
- J Korean Assoc Oral Maxillofac Surg.
- 1997 Jul;23(3):374-387.
The cell cycle is composed of G1, S, G2 and M phase. The transitions between different phases are regulated at checkpoint such as Start(restriction), S phase and mitotic checkpoint. These... -
- CITED
-
- Close
- SHARE
-
- Close
- Overexpression of USF Increases TGF-beta1 Protein Levels, But G1 Phase Arrest was not Induced in FRTL-5 Cells
-
Kim KS, Jung HS, Chung YJ, Jung TS, Jang HW, Lee MS, Kim KW, Chung JH
- KMID: 1783075
- J Korean Med Sci.
- 2008 Oct;23(5):870-876.
- doi: 10.3346/jkms.2008.23.5.870
Transforming growth factor-beta1 (TGF-beta1) is a potent inhibitor of cellular growth and proliferation by G1 phase arrest or apoptosis. We investigated the association of TGF-beta1 with the anti-proliferative effect of... -
- CITED
-
- Close
- SHARE
-
- Close
