- Which treatment modality should we choose for advanced hepatocellular carcinoma?
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Kim DY
- KMID: 1117690
- Korean J Hepatol.
- 2010 Dec;16(4):353-354.
- doi: 10.3350/kjhep.2010.16.4.353
No abstract available. -
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- A Case of Severe Coronary Spasm Associated with 5-Fluorouracil Chemotherapy
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Kim SM, Kwak CH, Lee B, Kim SB, Sir JJ, Cho WH, Choi SK
- KMID: 1776527
- Korean J Intern Med.
- 2012 Sep;27(3):342-345.
- doi: 10.3904/kjim.2012.27.3.342
Cardiotoxicity associated with 5-fluorouracil (FU) is an uncommon, but potentially lethal, condition. The case of an 83-year-old man with colon cancer who developed chest pain during 5-FU infusion is presented.... -
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- Hand-Foot Syndrome with Scleroderma-like Change Induced by the Oral Capecitabine: A Case Report
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Lee SD, Kim HJ, Hwang SJ, Kim YJ, Nam SH, Kim BS
- KMID: 1091871
- Korean J Intern Med.
- 2007 Jun;22(2):109-112.
- doi: 10.3904/kjim.2007.22.2.109
Hand-foot syndrome (HFS) is a well-known adverse event associated with capecitabine, a prodrug of 5-Fluorouracil (5-FU). HFS manifests as acral erythema, with swelling and dysesthesia of the palms and plantar... -
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- Distribution of 5-Fluorouracil-14C in Body Tissues after Systemic and Regional Administration in Gastric Cancer
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Min JS, Ban JM, Kim MW, Kim CK, Ryu KJ
- KMID: 693031
- Yonsei Med J.
- 1986 Sep;27(3):200-204.
- doi: 10.3349/ymj.1986.27.3.200
This study was to determine which of two routes of administration of 5-fluorouracil (5-FU) is more effective, by measuring the radioactvity in the body tissues of gastric cancer patients after... -
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- Systemic Chemotherapy in Advanced Pancreatic Cancer
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Lee HS, Park SW
- KMID: 2411959
- Gut Liver.
- 2016 May;10(3):340-347.
- doi: 10.5009/gnl15465
Pancreatic cancer remains one of the most lethal cancers. These patients often have multiple symptoms, and integrated supportive care is critical in helping them remain well for as long as... -
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- FOLFIRI as Second-line Chemotherapy after Failure of FOLFOX4 in Advanced Colorectal Cancer: A Korean Single-center Experience
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Kim JH, Park SJ, Park MI, Moon W, Kim SE, Ku KH, Song SE, Kim JH
- KMID: 1711301
- Korean J Gastroenterol.
- 2014 Jan;63(1):18-24.
- doi: 10.4166/kjg.2014.63.1.18
BACKGROUND/AIMS: The incidence of colorectal cancer has been increasing every year in Korea. Irinotecan- or oxaliplatin-based regimens including biologic agents are known to be effective in patients with advanced colorectal... -
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- Combination of oxaliplatin, fluorouracil, and leucovorin in the treatment of fluoropyrimidine-pretreated patients with metastatic colorectal cancer
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Lee JH, Lee JH, Kim TW, Lee KH, Kang YK, Lee JS, Kim SH, Kim HC, Yu CS, Kim JC, Kim WK
- KMID: 1066497
- J Korean Med Sci.
- 2001 Feb;16(1):69-74.
- doi: 10.3346/jkms.2001.16.1.69
There has been no standard therapy for patients with metastatic colorectal cancer who have failed to first-line fluorouracil-based treatment. The present study was designed to assess the efficacy and toxicities... -
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- Phase II Study of Low-dose Paclitaxel and Cisplatin as a Second-line Therapy after 5-Fluorouracil/Platinum Chemotherapy in Gastric Cancer
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Lee KW, Kim JH, Yun T, Song EK, Na II, Shin H, Oh SY, Choi IS, Oh DY, Kim DW, Im SA, Kim TY, Lee JS, Heo DS, Bang YJ, Kim NK
- KMID: 1785799
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S115-S121.
- doi: 10.3346/jkms.2007.22.S.S115
This study was performed to evaluate the efficacy and toxicity of low-dose paclitaxel/cisplatin chemotherapy in patients with metastatic or recurrent gastric cancer that had failed 5-fluorouracil/platinum-based chemotherapy. Thirty-two patients with... -
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- The Bacterial Protein Azurin Enhances Sensitivity of Oral Squamous Carcinoma Cells to Anticancer Drugs
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Choi JH, Lee MH, Cho YJ, Park BS, Kim S, Kim GC
- KMID: 1108070
- Yonsei Med J.
- 2011 Sep;52(5):773-778.
- doi: 10.3349/ymj.2011.52.5.773
PURPOSE: Surgical therapy is the primary treatment for oral cancer, but it can cause facial distortion. Therefore, if anticancer drugs are effective against oral cancer, they may be used preferentially.... -
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- A Phase II Study of Combination Chemotherapy with Gemcitabine, 5-fluorouracil, and Cisplatin for Advanced Pancreatic Cancer
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Choi SB, Lee HY, Yuh YJ, Kim SR
- KMID: 772776
- Korean J Gastroenterol.
- 2005 May;45(5):348-353.
BACKGROUND/AIMS: Gemcitabine has been the standard regimen for advanced pancreatic cancer, but the effect on the response rate and survival is still disappointing, leading to many trials of combination... -
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- Phase II Study of Paclitaxel, Cisplatin, and 5-Fluorouracil Combination Chemotherapy in Patients with Advanced Gastric Cancer
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Hwang J, Cho SH, Shim HJ, Lee SR, Ahn JS, Yang DH, Kim YK, Lee JJ, Kim HJ, Chung IJ
- KMID: 1785814
- J Korean Med Sci.
- 2008 Aug;23(4):586-591.
- doi: 10.3346/jkms.2008.23.4.586
This phase II study evaluated the efficacy and safety of combination chemotherapy with paclitaxel, cisplatin, and 5-fluorouracil (5-FU) in advanced gastric cancer. Patients with histologically confirmed gastric adenocarcinoma were eligible... -
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- Irinotecan, Continuous 5-Fluorouracil, and Low dose of Leucovorin (modified FOLFIRI) as First Line of Therapy in Recurrent or Metastatic Colorectal Cancer
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Lee MA, Byun JH, Shim BY, Woo IS, Kang JH, Hong YS, Lee KS, Choi MG, Chang SK, Oh ST, Choi SI, Lee DS
- KMID: 1782231
- Korean J Intern Med.
- 2005 Sep;20(3):205-209.
- doi: 10.3904/kjim.2005.20.3.205
BACKGROUND: Irinotecan, in combination with 5-fluorouracil (5-FU) and a high dose of leucovorin (LV), known as FOLFIRI regimen, has shown activity in recurrent or metastatic colorectal cancer. Therefore, we evaluated... -
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- A Case of Advanced Gastric Cancer Presenting as Multiple Colonic Lymphoid Hyperplasia
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Lee IH, Lee J, Byeon SW, Lee H, Huo S, Yoon SB, Kim JS, Lee SH, Roh SY
- KMID: 2373345
- Korean J Gastroenterol.
- 2015 Oct;66(4):221-226.
- doi: 10.4166/kjg.2015.66.4.221
Gastric cancer frequently disseminates to the liver, lung, and bone via hematogeneous, lymphatic, or peritoneal routes. However, gastric adenocarcinoma that metastasize to the colon and that shows typical linea platisca... -
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- A randomized trial comparing cisplatin plus 5-fluorouracil with or without levamisole in operable gastric cancer
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Choi JS, Lee KH, Ahn MJ, Lee JS, Lee JH, Zang DY, Suh CW, Kim SW, Kim WG, Kim JC, Kim S, Park KC, Lee MS, Kim SH
- KMID: 1051578
- Korean J Intern Med.
- 1997 Jun;12(2):155-162.
OBJECTIVES: To determine the effectiveness and toxicity when levamisole was added to the adjuvant combination chemotherapy in patients with operable gastric cancer. METHODS: After en bloc resection of gastric cancer... -
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- A Case of Severe Bevacizumab-induced Ischemic Pancolitis, Treated with Conservative Management
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Lee HN, Lee MA, Kim SW, Lim Y, Lee H, Lee HM, Won HS, Chun SH
- KMID: 1792814
- Korean J Gastroenterol.
- 2011 Jul;58(1):42-46.
- doi: 10.4166/kjg.2011.58.1.42
Bevacizumab (Avastin(R)) is a monoclonal antibody against the vascular endothelial growth factor (VEGF) receptor that increases the overall survival rate when added to standard chemotherapy regimens in patients with metastatic... -
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- Combination treatment with intrahepatic arterial infusion and intratumoral injection chemotherapy in patients with far-advanced hepatocellular carcinoma and arterioportal or arteriovenous shunts: preliminary results
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Kim JS, Park YM, Kim NY, Yun HK, Lee KJ, Kim BH, Park SJ, Yeon JW, Jung G
- KMID: 1015571
- Korean J Hepatol.
- 2011 Jun;17(2):120-129.
- doi: 10.3350/kjhep.2011.17.2.120
BACKGROUND/AIMS: Combination treatment consisting of hepatic arterial infusion chemotherapy with epirubicin and cisplatin (HAIC-EC) and systemic infusion of low-dose 5-fluorouracil (5-FU) are sometimes effective against advanced hepatocellular carcinoma (HCC). However,... -
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- Efficacy of Hepatic Arterial Infusion Therapy for Advanced Hepatocellular Carcinoma Using 5-Fluorouracil, Epirubicin and Mitomycin-C
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Hwang JY, Jang BK, Kwon KM, Chung WJ, Park KS, Cho KB, Hwang JS, Ahn SH, Kim GC, Kim YH, Choi JS, Kwon JH
- KMID: 2439746
- Korean J Gastroenterol.
- 2005 Feb;45(2):118-124.
BACKGROUND/AIMS: Prognosis of advanced hepatocellular carcinoma (HCC) treated by conventional therapies has been considered to be poor. The aim of this study was to evaluate the efficacy of hepatic... -
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- Efficacy and Safety of Hepatic Arterial Infusion of Fluorouracil with Leucovorin as Salvage Treatment for Refractory Liver Metastases from Colorectal Cancer
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Lee HJ, Lee YS, Lee KW, Kim SY, Yoon CJ, Shin DY, Lee YG, Choi SY, Kang SG, Kang SB, Kim JH
- KMID: 1036155
- Korean J Intern Med.
- 2011 Mar;26(1):82-88.
- doi: 10.3904/kjim.2011.26.1.82
BACKGROUND/AIMS: Limited options remain for patients with metastatic colorectal cancer (CRC) after failure of standard systemic chemotherapy. Readministration of chemotherapeutic agents by hepatic arterial infusion (HAI) has the rationale of... -
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- Efficacy of Capecitabine Plus Oxaliplatin Combination Chemotherapy for Advanced Pancreatic Cancer after Failure of First-Line Gemcitabine-Based Therapy
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Chung KH, Ryu JK, Son JH, Lee JW, Jang DK, Lee SH, Kim YT
- KMID: 2412198
- Gut Liver.
- 2017 Mar;11(2):298-305.
- doi: 10.5009/gnl16307
BACKGROUND/AIMS: Second-line chemotherapy in patients with advanced pancreatic ductal adenocarcinoma (PDAC) that progresses following gemcitabine-based treatment has not been established. This study aimed to investigate the efficacy and safety of... -
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- Photodynamic Therapy Plus Chemotherapy Compared with Photodynamic Therapy Alone in Hilar Nonresectable Cholangiocarcinoma
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Wentrup R, Winkelmann N, Mitroshkin A, Prager M, Voderholzer W, Schachschal G, Jürgensen C, Büning C
- KMID: 2411976
- Gut Liver.
- 2016 May;10(3):470-475.
- doi: 10.5009/gnl15175
BACKGROUND/AIMS: Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS: We... -
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