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A Case of Life-Threatening Supraventricular Tachycardia Related to Flecainide Toxicity

Cheon SS, Song JH, Bae MH, Lee JH, Yang DH, Park HS, Chae SC

  • KMID: 2269266
  • Korean J Med.
  • 2014 Jul;87(1):72-76.
Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal...
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Flecainide-Induced Torsade de Pointes Successfully Treated with Intensive Pharmacological Therapy

Jung HW, Kwak JJ, Namgung J

Flecainide acetate is a potent class IC anti-arrhythmic drug with a major sodium channel blocking effect. Flecainide toxicity can cause myocardial impairment and precipitate circulatory collapse. It may also result...
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Perimortem cesarean section in a pregnant woman with flecainide-induced ventricular tachycardia: A case report

Lee JY, Song E, Suh JH, Choi WJ, Cho SK, Han SM

  • KMID: 2169154
  • Anesth Pain Med.
  • 2012 Jan;7(1):76-79.
Flecainide is a drug used to manage supraventricular and ventricular arrhythmias. It is also effective in the treatment of fetal tachyarrhythmia through administration to the mother. However, flecainide toxicity may...
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Effects of Intrathecal Flecainide for Pain Behavior in Formalin Test and Hemodynamics in Rat

Park HC, Kim CM, Choi JI, Jeong SW, Bae HB, Park GD, Yoon MH

BACKGROUND: The antinociceptive activity of drugs with a sodium channel blocker is an anti-arrhythmic agent belonging to the Ic class. Although the antinociceptive effects of flecainide have been demonstrated in...
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A Case of Acute Ventricular Capture Threshold Rise Associated with Flecainide Acetate

Kang TS, Yoon YW, Park S, Hong BK, Kim D, Kwon HM, Kim HS

Antiarrhythmic agents may increase capture threshold, but this is rarely of clinical significance. Flecainide acetate, a class IC agent, is reported to have a significant effect on the myocardial capture...
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Intractable Atrial Flutter Successfully Treated with Flecainide and Propranolol in a Premature Infant

Lee MJ, Ahn SH, Kim JH, Kim SY, Ban JE

Although Atrial flutter (AFL) in newborn infant with normal cardiac anatomy has benign clinical course, an intractable AFL is associated with an increased risk of development of heart failure and...
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Wide QRS tachycardia during treatment with class ic antiarrhythmic agents in a patient with atrial fibrillation: report of 2 cases

Shim JK, Lee DI, Chang BI, Shin HJ, Byun KH, Kim YW, Kim JH

  • KMID: 2252730
  • Korean J Med.
  • 2003 Nov;65(Suppl 3):S727-S732.
Wide QRS tachycardia may represent a rare proarrhythmic effect of some antiarrhythmic agents. Class Ic antiarrhythmic agents produce rate- dependent ventricular conduction slowing due to use-dependent sodium channel blockade, causing...
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Comparision of thr Efficacy of Propafenone and Flecainide in Patients with Atrial Fibrillation

Kim DS, Koh CW, Cho HK, Kim TY, Ahn SK, Lee MH, Kim SS

BACKGROUND: Atrial fibrillation is one of the most common cardiac arrhythmias which has been recieved relatively little attention until recently.Despite the variety of treatment modalities including drugs,surgery,catheter ablation and devices,the...
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Two cases of atrial flutter with fetal hydrops: successful fetal drug therapy

Won HS, Lee IS, Yoo HK, Yoo SJ, Ko JK, Lee PR, Kim A, Mok JE

We describe two cases of fetal atrial flutter associated with severe fetal hydrops which were unresponsive to digoxin but were successfully treated with flecainide acetate. Two cases of fetal...
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Flecainide Improve Sepsis Induced Acute Lung Injury by Controlling Inflammatory Response

Song J, Suh YJ, Lee HJ, Jang EA, Bae HB, Kwak SH

BACKGROUND: Flecainide is an antiarrhythmic agent that is used primarily in the treatment of cardiac arrhythmias. Some evidences also suggest that flecainide can participate in alveolar fluid clearance and inflammatory...
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Brugada syndrome manifested in postoperative period: A case report

Lee JH, Ro YJ, Yang HS

  • KMID: 1795962
  • Anesth Pain Med.
  • 2013 Jul;8(3):203-207.
We describe here a woman with Brugada syndrome revealed in postoperative period. A 48-year-old woman who underwent open biopsy of a tumor on her left distal femur under general anesthesia...
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The Effects of Flecainide Acetate on Inflammatory-Immune Response in Lipopolysaccharide-Stimulated Neutrophils and on Mortality in Septic Rats

Chung SY, Kim J, Bae HB, Tin TD, Ju W, Kwak SH

BACKGROUND: Flecainide acetate is a drug used primarily for cardiac arrhythmia. Some studies also imply that flecainide acetate has the potential to regulate inflammatory-immune responses; however, its mechanism of action...
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An Unusual Case of Exercise-Induced Idiopathic Brugada Electrocardiographic Pattern

Cho JH, Cho DK, Choi JY, Eun LY, Cho YH, Koh JH, Byun KH

An exercise-induced idiopathic Brugada electrocardiographic pattern during the effort phase is very rare. A 42-year-old male visited our cardiology clinic for chest discomfort. He has been treated for myocardial infarction...
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Supraventricular Tachycardia by Concealed Bypass Tract

Lee KH

Concealed bypass tract (CBT) results from incomplete development of the atrioventricular (AV) annulus. CBT conducts only in a retrograde direction, and therefore does not cause pre-excitation on standard electrocardiograms. The...
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Unmasking of the Idiopathic Brugada Electrocardiogram Pattern in a Febrile Patient with Pneumonia

Lee JB, Lee MY, Lee SJ, Hwang HJ, Park HK, Choi YS, Park CS

  • KMID: 2258882
  • Korean J Med.
  • 2011 Jun;80(Suppl 2):S166-S171.
We present the case of a 44-year-old man who presented with continuous chest pain and fever with pneumonia. Additionally, idiopathic Brugada ECG patterns were observed. The patient's initial electrocardiogram showed...
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Differing Electrophysiological Effects of Various Antiarrhythmic Drugs on the Cardiac Chamber in Atrial Fibrillation

Jang SY, Cho JG, Jung HK, Ki WJ, Lee KJ, Ko JS, Lee MG, Park KH, Sim DS, Yoon NS, Yoon HJ, Hong YJ, Park HW, Kim JH, Ahn Y, Jeong MH, Park JC, Kang JC

  • KMID: 2259290
  • Korean J Med.
  • 2011 Jun;80(6):672-679.
BACKGROUND/AIMS: Long-term antiarrhythmic drug therapy remains the principal approach for suppressing atrial fibrillation (AF) and maintaining sinus rhythm. In this study, we examined the differing electrophysiological effects of various antiarrhythmic...
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Photosensitivity caused by dronedarone: A case report

Lee JH, Kim SM, Jung CG, Park HS, Shin YS

Dronedarone is a new antiarrhythmic drug for the treatment of nonpermanent atrial fibrillation. Compared with amiodarone, it is regarded as a safe medication due to its structural differences. In this...
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Cost-Effectiveness of Rate- and Rhythm-Control Drugs for Treating Atrial Fibrillation in Korea

Kim M, Kim W, Kim C, Joung B

PURPOSE: Although the economic and mortality burden of atrial fibrillation (AF) is substantial, it remains unclear which treatment strategies for rate and rhythm control are most cost-effective. Consequently, economic factors...
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Two cases of sudden cardiac death syndrome associated with right bundle branch block and ST segment elevation

Park SS, Nam GB, Choi KJ, Song JK, Kim JJ, Park SJ, Park JH, Kim YH

In 1992, Brugada described clinical features of patients with aborted sudden cardiac death who showed no demonstrable heart disease and a peculiar ECG pattern consisting of right bundle branch block...
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Tachyarrhythmia:Prenatal Diagnosis, Management and Perinatal Outcome

Jung E, Won HS, Kim SK, Shim JY, Lee PR, Kim A, Park IS

  • KMID: 1838173
  • Korean J Perinatol.
  • 2005 Sep;16(3):230-236.
OBJECTIVE: To review the diagnosis, treatment, and perinatal outcome of fetal tachyarrhythmias. METHODS: We reviewed the medical records of pregnant women diagnosed with fetal tachyarrhythmia at Asan Medical Center from June...
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