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A Critical Involvement of Glutamatergic Neurons in the Anterior Insular Cortex for Subdiaphragmatic Vagotomy-induced Analgesia

Kim YJ, Lee GJ, Shim SW, Kim D, Oh SB

Subdiaphragmatic vagotomy (SDV) is known to produce analgesic effect in various pain conditions including not only visceral pain but also somatic pain. We aimed to determine brain mechanisms by which...
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Caenorhabditis elegans Connectomes of both Sexes as Image Classifiers

Park C, Kim JS

  • KMID: 2542310
  • Exp Neurobiol.
  • 2023 Apr;32(2):102-109.
  • doi: 10.5607/en23004
Connectome, the complete wiring diagram of the nervous system of an organism, is the biological substrate of the mind. While biological neural networks are crucial to the understanding of neural...
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Impaired Cholesterol Metabolism, Neurons, and Neuropsychiatric Disorders

Cheon SY

Cholesterol metabolism plays an essential role in cellular functions (including as a component of the plasma membrane, as an energy source, and in hormone production) under normal conditions. Dysregulated cholesterol...
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Intact Recognition Memory and Altered Hippocampal Glucocorticoid Receptor Signaling in Fkbp5-deficient Mice Following Acute Uncontrollable Stress

Jeon YJ, Choi BR, Park MS, Jang YS, Yoon S, Lyoo IK, Han JS

The FK506 binding protein 5 (FKBP5) is a co-chaperone that regulates the activity of the glucocorticoid receptor (GR) and has been reported to mediate stress resilience. This study aimed to...
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mGluR1 Regulates the Interspike Interval Threshold for Dendritic Ca2+ Transients in the Cerebellar Purkinje Cells

Jang DC, Ryu C, Chung G, Kim SK, Kim SJ

Ca2+ transients can be observed in the distal dendrites of Purkinje cells (PCs) despite their lack of action potential backpropagation. These Ca2+ events in distal dendrites require specific patterns of PC...
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Aberrant Resting-state Functional Connectivity in Complex Regional Pain Syndrome: A Network-based Statistics Analysis

Hong H, Suh C, Namgung E, Ha E, Lee S, Kim RY, Song Y, Oh S, Lyoo IK, Jeong H, Yoon S

  • KMID: 2542311
  • Exp Neurobiol.
  • 2023 Apr;32(2):110-118.
  • doi: 10.5607/en23003
Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder. Pain catastrophizing, characterized by magnification, rumination, and helplessness, increases perceived pain intensity and mental distress in CRPS patients. As...
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