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Drug Rash With Eosinophilia and Systemic Symptoms Syndrome Induced by Chloral Hydrate in Early Childhood

Yoo SD, Kim SG, Kim SH, Kim HY

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by...
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A Case of Drug Rash with Eosinophilia and Systemic Symptoms Associated with Valproic Acid and Olanzapine Treatment in Patient with Bipolar Disorder

Lee U, Lim SW

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening, medication-induced hypersensitivity reaction with long latency. It is characterized by fever, rash, leukocytosis with eosinophilia, atypical lymphocytosis,...
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Successful desensitization of a patient with albumin hypersensitivity

Jung SY, Choi YJ, Lee SH, Kang HR, Suh DI

There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug...
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Piperacillin/Tazobactam-Associated Hypersensitivity Syndrome with Overlapping Features of Acute Generalized Exanthematous Pustulosis and Drug-Related Rash with Eosinophilia and Systemic Symptoms Syndrome

Kim TI, Jeong KH, Shin MK, Kim NI

Acute generalized exanthematous pustulosis (AGEP) is a rare disorder characterized by acute onset of erythematous and edematous eruptions with sterile pustules, accompanied by fever, and a self-limiting condition thought to...
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Trichloroethylene Hypersensitivity Syndrome: Should Be Considered When Diagnosing DRESS Syndrome

Kang YJ, Lee J, Ahn J, Park S, Shin MY, Lee HW

Trichloroethylene (TCE) is an organic solvent that is used for degreasing and removing impurities from metal parts. However, this solvent's characteristics and hypersensitivity can produce clinical patterns and laboratory data...
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Rapid-onset of severe tigecycline-induced coagulopathy in drug reaction with eosinophilia and systemic symptom syndrome

Jeong YJ, Ghanh B, Lee JW, Park J, Kim TB, Cho YS, Moon HB, Kwon HS

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome-also known as drug-induced hypersensitivity syndrome-is an uncommon disease entity that manifests as fever, skin rash, blood cell abnormalities, lymphadenopathy, and often...
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Comparison of Diagnostic Criteria and Determination of Prognostic Factors for Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome

Kim DH, Koh YI

PURPOSE: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is characterized by prolonged clinical symptoms even after the withdrawal of the culprit drug. Different criteria to diagnose DRESS syndrome...
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Recent advances of pharmacogenomics in severe cutaneous adverse reactions: immune and nonimmune mechanisms

Dao RL, Su SC, Chung WH

Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) are severe cutaneous adverse reactions (SCAR) which are majorly caused by drugs. Though the...
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Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Induced by Lamotrigine

Han SH, Hur MS, Youn HJ, Roh NK, Lee YW, Choe YB, Ahn KJ

Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a type of severe adverse drug-induced reaction. Dermatologists should make a quick diagnosis and provide appropriate treatment for DRESS syndrome...
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Dapsone-induced drug reaction with eosinophilia and systemic symptoms syndrome, misdiagnosed as lymphoma

Shin B, Park SY, Yoon SY, Shin EH, Yang YJ, Cho HJ, Jang IY, Kang DU, Kim TB, Cho YS, Moon HB, Kwon HS

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a life-threatening adverse drug reaction with systemic manifestations. Dapsone is known to be useful for treatment of leprosy and various...
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Analysis of 13 Cases of Severe Drug Reactions due to Allopurinol

  • KMID: 2234389
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Sep;26(3):225-232.
BACKGROUND: Allopurinol-induced hypersensitivity reactions are rare but increasing recently in clinical practice; however, little has been known about its clinical characteristics and underlying mechanism. OBJECTIVE: The goal of this study was...
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Concomitant Drug Reaction with Eosinophilia and Systemic Symptom Syndrome from Ethambutol and Autoimmune Hepatitis from Isoniazid

Choi JH, Heo NY, Park SH, Park CS, Jo KM, Kim WG, Nam KH

Anti-tuberculosis drugs can produce levels of hepatotoxicity ranging from mild elevation of aminotransferase to severe acute hepatitis. A few cases of drug-induced autoimmune hepatitis or the drug reaction with eosinophilia...
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Allopurinol Induced DRESS Syndrome in Patients with Chronic Kidney Disease

Lee SY, Kim NH, Jeong S, Jang DS, Lee YM, Na KR, Lee KW, Shin YT

  • KMID: 1597870
  • Korean J Nephrol.
  • 2006 Jul;25(4):681-687.
Allopurinol decreases serum uric acid levels in hyperuricemic patients and may slow the progression of renal diseases, Allopurinol-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome, which was called...
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DRESS (drug reaction with eosinophilia and systemic symptom) syndrome caused by both first-line and second-line antitubercular medications: A case report with a brief literature review

Hwang YH, Jang DY, Kang SY, Sohn KH, Kang DY, Lee CH, Kang HR

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but potentially fatal drug-induced systemic hypersensitivity response characterized by erythematous eruption, fever, leukocytosis with eosinophilia, and internal organ...
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Eosinophilic Polymyositis and DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) Syndrome by Antitubercular Agents

Shin KS, Park MS

Eosinophilic polymyositis (EPM) is a heterogeneous disorder characterized by eosinophilic infiltration into skeletal muscles. EPM is occasionally associated with a systemic disease, such as hypereosinophilic syndrome, connective tissue disease, or...
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Toxic epidermal necrolysis induced by deflazacort

Youn D, Kim MH, Koh SW, Kim JW, Yoon SE, Jeon HK, Cho YJ

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions to drugs, which carry significant morbidities and mortalities. Although SJS and TEN can be treated by corticosteroids...
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A case of toxic epidermal necrolysis induced by cytomegalovirus infection followed by DRESS (drug reaction with eosinophilia and systemic symptoms)

Sim DW, Son S, Yu J, Koh YI

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. Although viral reactivation is associated with DRESS syndrome, its role in...
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Severe Cutaneous Adverse Reaction

Yang MS, Jung JW, Kang HR

Severe adverse cutaneous reactions (SCARs) include Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS). Although recent advances in pharmacogenomics have revealed the association...
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A retrospective study on sequential desensitization-rechallenge for antituberculosis drug allergy

Thong BY, Chia FL, Tan SC, Tan TC, Leong KP, Tan JW, Tang CY, Hou JF, Chan GY, Chng HH

BACKGROUND: Antituberculosis (anti-TB) drug allergy often involves multiple concurrently administered drugs which subsequently need to be reinitiated as no better alternatives exist. OBJECTIVE: To describe the results of tailored sequential desensitization-rechallenge...
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Human leukocyte antigen-associated severe cutaneous adverse drug reactions: from bedside to bench and beyond

Nguyen DV, Vidal C, Chu HC, van Nunen

Despite their being uncommon, severe cutaneous adverse drug reactions (SCARs) result in a very great burden of disease. These reactions not only carry with them a high mortality (10%–50%) and...
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