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Totpgraphic distribution. ultrastructure and synaptic organization of dopaminergic neurons in the retinae of rodents: I. topographic distribution

Chun MH, Lee MY, Oh SJ, Chung JW

  • KMID: 1686720
  • Korean J Anat.
  • 1992 Mar;25(1):31-39.
No abstract available.
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Morphological Changes in Dopaminergic Neurons in Selective Parkinson's Rat Model

Kim KM, Kim YS

  • KMID: 2067354
  • J Korean Neurosurg Soc.
  • 1996 Jan;25(1):16-22.
The great majority of studies on tissue implantation in Parkinson's rat models have been performed. Recently the new rat model which is similar to clinical Parkinson's disease was developed. The...
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Topographic distribution, ultrastructure and synaptic organization of dopaminergic neurons in the retina of redents II. ultrastructure and synaptic organization

Chun MH, Lee MY, Han SH, Oh SJ, Chung JW

  • KMID: 1686710
  • Korean J Anat.
  • 1992 Jun;25(2):168-178.
No abstract available.
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FGF8 is Essential for Functionality of Induced Neural Precursor Cell-derived Dopaminergic Neurons

Lim MS, Lee SY, Park CH

Induced neural precursor cells (iNPCs) are one source of transplantable dopaminergic neurons used in cell therapy for Parkinson's disease. In the present study, we demonstrate that iNPCs can be generated...
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Direct Differentiation of Adult Ocular Progenitors into Striatal Dopaminergic Neurons

Ahmad I, Zhao X, Parameswaran S, Destache C, Rodriguez-Sierra J, Thoreson W, Ahmad H, Sorrentino J, Balasubramanian S

Parkinson's disease, characterized by motor dysfunction due to the loss of nigrostriatal dopaminergic neurons, is one of the most prevalent age-related neurodegenerative disorders. Given there is no current cure, the...
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Neurogenesis and neuronal migration of dopaminergic neurons during mesencephalon development in mice

Kim MK, Lee SJ, Vasudevan , Won C

Dopaminergic neurons are one of the major neuronal components in the brain. Mesencephalon dopamine (DA) neurogenesis takes place in the ventricular zone of the floor plate, when DA progenitors divide...
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Changes of Dopaminergic Neurons in Parkinson's Rat Model after Fetal Striatal Transplantation

Kim YS, Chung SS

  • KMID: 2018873
  • J Korean Neurosurg Soc.
  • 1996 Feb;25(2):260-268.
The strategies of the transplantation of fetal brain tissue for the neurodegenerative disease have been studied. Clinical trials on the transfer of the neurons of other cells compensating for the...
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Prospect of cell therapy for Parkinson's disease

Pawitan JA

The hallmark of Parkinson's disease is on-going degeneration of dopaminergic neurons in the substantia nigra, which may be due to various etiologies. Various approaches to alleviate symptoms are available, such...
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Imaging of Dopaminergic System in Movement Disorders

Kim YK, Kim SE

  • KMID: 2313033
  • Nucl Med Mol Imaging.
  • 2007 Apr;41(2):132-140.
Parkinson's disease is a common neurodegenerative disorder that is mainly caused by dopaminergic neuron loss in the substantia nigra. Several radiopharmaceutics have been developed to evaluate the integrity of dopaminergic...
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Cytotoxic Effect of 6-OHDA on the Dopaminergic Neurons and Astrocytes in the Dorsal Raphe Nucleus of the Rat

Hong ES, Nam SA, Jo SM, Kang TC, Won MH, Choi CD

  • KMID: 2040100
  • Korean J Anat.
  • 1999 Aug;32(4):553-561.
This study was designed to clarify the cytotoxic effects of 6-hydroxydopamine (6-OHDA) on the dopaminergic neurons and astrocytes in the dorsal raphe nucleus (DRN), and to investigate neurodegenerative changes by...
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Efficacy of Embryonic Stem Cell-derived Dopaminergic Neurons and E12 Mesencephalic Neuronal-precursor Derived Dopaminergic Neurons as a Source for Transplantation in Parkinsonian Rats

Koh HC, Park CH, Jeon BS, Lee SH

  • KMID: 2195076
  • J Korean Neurol Assoc.
  • 2003 Jun;21(3):289-296.
BACKGROUND: This study was performed to compare efficiency of embryonic stem (ES) cell-derived dopaminergic (DA) neurons from E12 mesencephalic neuronal-precursor derived DA neuron, and to assess the value of these...
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Effects of Fetal Nondopaminergic Cortical Tissue Transplantation in the Rat Parkinsonian Model

Chang JW, Chung SS

  • KMID: 1954681
  • J Korean Neurosurg Soc.
  • 1994 May;23(5):487-498.
Fetal dopaminergic or nondopaminergic cortical tissues were implanted directly into the denervated striatum of partial lesioned rat parkinsonian models. After transplantation, at rats were behaviourally tested with apomorphine and sacrificed...
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The Effects of Unilateral Dopaminergic Deafferentation on the Expression of mRNAs of Neurotrophic Factors

Park MK, Kim H, Lee DH

  • KMID: 1957217
  • J Korean Neurol Assoc.
  • 1995 Sep;13(3):425-437.
Recently protective and supportive functions of neurotrophic factors on dopaminergic neurons have been reported. In this study, in situ hybridization histochemistry with "S-labeled oligonucleotide probes for brain-derived factor (BDNF) and...
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Relationship between Microglial Activation and Dopaminergic Neuronal Loss in 6-OHDA-induced Parkinsonian Animal Model

Lee JS, Lee JY, Cho WG, Yang YC, Cho BP

This study assessed the dynamics of morphological and immunophenotypic properties of activated microglia in a 6-hydroxydopamine (6-OHDA) induced Parkinsonian animal model. Neurodegeneration in the substantia nigra pars compacta (SNc) was...
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Migratory defect of mesencephalic dopaminergic neurons in developing reeler mice

Kang WY, Kim SS, Cho SK, Kim S, Suh-Kim H, Lee YD

Reelin, an extracellular glycoprotein has an important role in the proper migration and positioning of neurons during brain development. Lack of reelin causes not only disorganized lamination of the cerebral...
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Ultrastructural Localization of Dopaminergic Receptors in the Amygdala of Rat

Lee HL

The present study was performed to identify the dopaminergic receptor sites in rat amygdala. Identification of the receptor sites at ultrastructrual level has been done by autoradiography after cerebral ventricular...
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Alteration of Striatal Tetrahydrobiopterin in Iron-Induced Unilateral Model of Parkinson's Disease

Aryal B, Lee JK, Kim HR, Kim HG

It has been suggested that transition metal ions such as iron can produce an oxidative injuries to nigrostriatal dopaminergic neurons, like Parkinson's disease (PD) and subsequent compensative increase of tetrahydrobiopterin...
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Dopaminergic Neurons in the Diencephalon of Striped Field Mouse[Apodemus agrarius coreae]

Jung YG, Lee NS, Min SH, Kim MG

  • KMID: 2224602
  • Korean J Anat.
  • 1997 Dec;30(6):609-622.
The distributions and morphological characteristics of neurons displaying immunoreactivity to the catecholamine synthetic enzymes, tyrosine hydroxylase[TH], dopamine-beta-hydroxylase[DBH], and phenyletha-nolamine-N-methyltransferase[PNMT] were examined in the adjacent sections of the diencephalon of the...
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An Autoradiographic Study on the Rat Neostriatal Dopamine Receptor Changes after 6-hydroxydopamine Injection into the Medial Prefrontal Cortex

Kwon JS, Lee DY, Woo JI

  • KMID: 2340296
  • J Korean Neuropsychiatr Assoc.
  • 1999 Mar;38(2):408-418.
The frontal cortex of rat is innervated by dopaminergic pathway(mesocortical pathway) arising from ventral tegmental area. Several studies have suggested that mesocortical dopaminergic neurons may modulate the function of dopaminergic...
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Study on Catecholaminergic Neurons in Central Pathways Supplying the Vagus Nerve

Hwang KM, Lee BH, Kim EA, Kim MO, Baik SH, Lee BY

  • KMID: 2092635
  • Korean J Anat.
  • 1998 Feb;31(1):1-8.
This study aimed to carry out the reconstruction of whole tract of the vagus nerve using new powerful neurotracer which can migrate easily to the neighboring neurons through synapse and...
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