- Role of tyrosine kinases in vascular contraction in deoxycorticosterone acetate-salt hypertensive rats
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Yeum CH, Jun JY, Choi HS
- KMID: 1554765
- Korean J Physiol Pharmacol.
- 1997 Oct;1(5):547-553.
It has been known that activation of tyrosine kinases is involved in signal transduction. Role of the tyrosine kinase in vascular smooth muscle contraction was examined in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Male... -
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- Altered Calcium Current of the Vascular Smooth Muscle in Renal Hypertension
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Nam SC, Jeong HJ, Kim W, Lee J
- KMID: 2285229
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):351-356.
The present study was aimed at investigating whether the calcium current in the vascular smooth muscle (VSM) cells is altered in renal hypertension. Two-kidney, one clip (2K1C) and deoxycorticosterone acetate (DOCA)-salt hypertension were... -
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- Effects of Tempol on Blood Pressure and Tissue Oxidative Stress in DOCA-alt and L-AME-nduced Hypertension
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Cho YW, Cho JW, Bae EH, Kim SW, Ma SK, Choi KC, Lee J
- KMID: 1597797
- Korean J Nephrol.
- 2006 Jul;25(4):525-531.
BACKGROUND: Effects of oxidative stress on the development of deoxycorticosterone acetate (DOCA)-salt or N(G)-nitro-L-arginine (L-NAME) hypertension were examined. METHODS: Male Sprague-awley rats were treated with DOCA (200 mg/kg, subcutaneous)-salt or L-NAME... -
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- Effects of Tamoxifen in Deoxycorticosterone Acetate-salt Hypertensive Nephropahty
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Choi JS, Kim IJ, Kim CS, Bae EH, Ma SK, Lee JU, Kim SW
- KMID: 1838116
- J Korean Soc Hypertens.
- 2013 Dec;19(4):123-131.
- doi: 10.5646/jksh.2013.19.4.123
BACKGROUND: The present study was designed to evaluate the possible renoprotective effects of tamoxifen in deoxycorticosterone acetate (DOCA)-salt hypertensive (DSH) rats and its role in inflammation and fibrosis in the... -
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- Histone deacetylase inhibitor, CG200745, attenuates cardiac hypertrophy and fibrosis in DOCA-induced hypertensive rats
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Lee E, Song MJ, Lee HA, Kang SH, Kim M, Yang EK, Lee DY, Ro S, Cho JM, Kim I
- KMID: 2350504
- Korean J Physiol Pharmacol.
- 2016 Sep;20(5):477-485.
- doi: 10.4196/kjpp.2016.20.5.477
CG200745 is a novel inhibitor of histone deacetylases (HDACs), initially developed for treatment of various hematological and solid cancers. Because it is water-soluble, it can be administered orally. We hypothesized... -
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- Congenital Adrenal Hyperplasia with 21-hydroxylase Deficiencies in Twins
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Kim YD, Choi JH, Park JH, Park HJ, Jeon SS
- KMID: 2208493
- J Korean Pediatr Soc.
- 1994 Oct;37(10):1469-1473.
Congenital adrenal hyperplasia is inherited disorder of adrenal steroidogenesis. 21-hydroxylase deficiency is the most commone enzymatic defect and is divided into classic and late-onset or nonclassic forms. Both classic non-classic... -
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- Two cases of salt losing form of congenital adrenal hyperplasia
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Park KC, Chun HJ, Shin MJ, Kang SC
- KMID: 1946160
- J Korean Pediatr Soc.
- 1978 Sep;21(9):614-621.
We experienced 2 case of losing form of congenital adrenal hyperplasia which were regarded to be sucessfully controlled with hormonal replacement, DOCA and hydrocortisone. Case 1 was a 40 days-old... -
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- The Effects of Castration and Sex Hormone Administration on Lactic and Malic Dehydrogenase Activities in the Testis and the Prostate Tissues of Male Rabbits
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Kim HM, Choo KW
- KMID: 1679463
- Korean J Urol.
- 1967 Jun;8(1):1-8.
As a process to study the mechanism of steroid hormones at the molecular level,the activities of lactic dehydrogenase (L.D.) and malic dehydrogenase (M.D.),NAD-linked transhydrogenases, were measured in the testis and... -
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