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Expression Changes of c-Fos Protein of Rat Brain Following Pentylenetetrazol-induced Seizures

Kim EJ, Yoo KS, Hwang GK

  • KMID: 2137161
  • J Korean Child Neurol Soc.
  • 2001 May;9(1):49-58.
PURPOSE: The expression of c-Fos protein has been shown to be a useful marker for elevated levels of neuronal activity generated in the brain following different stimuli, including seizures. This...
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The Morphologic Changes of Parvalbumin- Immunoreactive Interneurons of the Dentate Gyrus in Kainate-Treated Mouse Hippocampal Slice Culture Epilepsy Model

Chung HS, Shin MY, Kim YH, Lee IG, Whang YT, Kim MS

  • KMID: 2207105
  • J Korean Pediatr Soc.
  • 2002 Dec;45(12):1551-1558.
PURPOSE: Loss of hippocampal interneurons in dentate gyrus has been reported in patients with severe temporal lobe epilepsy and in animals treated with kainic acid(KA). Interneurons contain Ca2+- binding protein...
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Temporal Change of Calbindin-D28k Immunoreactivity in the Dentate Gyrus of Voluntary Running Mouse

Moon M, Jeong JW, Huh Y, Kim J, Ahn H, Park C

  • KMID: 1937823
  • Korean J Anat.
  • 2006 Apr;39(2):119-128.
Voluntary running is known to dramatically increase the cell proliferation and neurogenesis in the dentate gyrus of the adult mouse hippocampus. However, it is crucial to realize that adding excitatory...
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Neurogenesis and Psychiatry: Focusing on Mood Disorders

Lee JS, Yang BH

  • KMID: 2340755
  • J Korean Neuropsychiatr Assoc.
  • 2002 Sep;41(5):796-804.
Up to now, the adult brain has been considered largely refractory to regeneration and new neuronal birth(neurogenesis). However, recent studies have clearly revealed that the adult hippocampus, specifically the dentate...
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Postnatal changes in glucose transporter 3 expression in the dentate gyrus of the C57BL/6 mouse model

Jung HY, Yim HS, Yoo DY, Kim JW, Chung JY, Seong JK, Yoon YS, Kim DW, Hwang IK

In this study, we observed the ontogenetic changes in glucose transporter 3 (GLUT3) immunoreactivity, a major neuronal GLUT, in the dentate gyrus of mouse brains at various ages: postnatal day...
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The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layer of Mouse Dentate Gyrus

Yoon MS, Moon M, Jeong JW, Kim J, Ahn H, Huh Y, Park C

  • KMID: 2283230
  • Korean J Phys Anthropol.
  • 2006 Dec;19(4):325-337.
Stress induces degeneration of brain structures and functions. Particularly, hippocampus is sensitive to stressful stimulations. In the present study, the change of synaptic related molecules in the mouse dentate gyrus...
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Protective Effect of Shenqi-wan on Traumatic Brain Injury-induced Delayed Apoptosis in Rat Hippocampal Dentate Gyrus

Kwon OB, Lim HH, Song YK, Lee JW, Kim YS, Kim CJ

Shenqi-wan, Oriental herbal medicine formulation, has been traditionally used for delayed mental and physical development in children, complications of diabetes, and glomerulonephritis. In the present study, the protective effect of...
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Change of peroxisome proliferator-activated receptor gamma expression pattern in the gerbil dentate gyrus after transient global cerebral ischemia

Lee CH, Won MH

Peroxisome proliferator-activated receptor gamma (PPARgamma) has various actions including the regulation of adipocyte differentiation, lipid metabolism and glucose homeostasis. In the present study, we examined the changes of PPARgamma immunoreactivity...
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Hypoxic Brain Injury with Bilateral Dentate Gyrus Involvement

Kang HG, Park SK, Ryu HU

No abstract available.
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Decrease in glucose transporter 1 levels and translocation of glucose transporter 3 in the dentate gyrus of C57BL/6 mice and gerbils with aging

Lee KY, Yoo DY, Jung HY, Baek L, Lee H, Kwon HJ, Chung JY, Kang SH, Kim DW, Hwang IK, Choi JH

In the present study, we compared the cell-specific expression and changes protein levels in the glucose transporters (GLUTs) 1 and 3, the major GLUTs in the mouse and gerbil brains...
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Calcium Influx is Responsible for Afterdepolarizations in Rat Hippocampal Dentate Granule Cells

Park WS, Lee SH

  • KMID: 2285243
  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):143-148.
Granule cells in dentate gyrus of hippocampus relay information from entorhinal cortex via perforant fiber to pyramidal cells in CA3 region. Their electrical activities are known to be closely associated...
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Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model

Yarishkin , Lee J, Jo S, Hwang EM, Lee CJ

Like neurons, astrocytes produce and release GABA to influence neuronal signaling. At the perforant path to dentate gyrus granule neuron synapse, GABA from astrocyte was found to be a strong...
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Vanillin and 4-hydroxybenzyl alcohol attenuate cognitive impairment and the reduction of cell proliferation and neuroblast differentiation in the dentate gyrus in a mouse model of scopolamine-induced amnesia

Kim YH, Park JH

4-Hydroxy-3-methoxybenzaldehyde (vanillin) and 4-hydroxybenzyl alcohol (4-HBA) are natural phenolic compounds, which present in many plants and have diverse biological properties. In this study, we examined effects of vanillin and 4-HBA...
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Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus

Kwon HJ, Jung HY, Hahn KR, Kim W, Kim JW, Yoo DY, Yoon YS, Hwang IK, Kim DW

Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized...
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Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe

Kim TS, Ko IG, Sung YH, Kim SE, Kim BK, Park SK, Shin MS, Kim CJ, Yoon SJ, Kim KH

This study was conducted to evaluate the effects of vardenafil (Levitra), a phosphodiesterase-5 (PDE-5) inhibitor, on cell proliferation in the hippocampal dentate gyrus and on 5-hyroxytryptamine (5-HT, serotonin) synthesis and...
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Hippocampal Neurogenesis and Phenotypic Differentiation after Pilocarpine-Induced Seizures in Young Mice

Park J, Ryu NY, Kim DW

  • KMID: 2059498
  • J Korean Child Neurol Soc.
  • 2012 Sep;20(3):170-178.
PURPOSE: Proliferation, differentiation, and survival of hippocampal dentate granule cells have been reported to be influenced by epileptic seizures in rodent epilepsy models. However, most studies have been done in...
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Effects of Long-term Adrenalectomy on Rat Hippocampal Neurons

Han SH

  • KMID: 2342674
  • J Korean Neurol Assoc.
  • 1998 Jun;16(3):372-380.
BACKGROUND: The central nervous system (CNS) is a well-known target site of steroid hormone action. Both the pyramidal neurons of Ammon's horn and the granule cells (GC) of the dentate...
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The Effect of Low Dose Radiation on the Neuronal Cell Proliferation in Diabetic Rats

Kim DS, Kang JO, Hong SE, Kim SK, Lee TH, Kim CJ

  • KMID: 1590159
  • J Korean Soc Ther Radiol Oncol.
  • 2005 Sep;23(3):157-160.
PURPOSE: To investigate the effect of low dose radiation on neuronal cell proliferation in diabetic rats. MATERIALS AND METHODS: A group of rats (first group) were divided into three subgroups (nondiabetic...
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Developmental changes in GABAA tonic inhibition are compromised by multiple mechanisms in preadolescent dentate gyrus granule cells

Pandit S, Lee GS, Park JB

The sustained tonic currents (I(tonic)) generated by γ-aminobutyric acid A receptors (GABA(A)Rs) are implicated in diverse age-dependent brain functions. While various mechanisms regulating I(tonic) in the hippocampus are known, their...
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Sustained Expression of Neuritin mRNA After Repeated Electroconvulsive Stimulations in the Rat Hippocampal Formation

Park KW, Kim IH, Sun W, Kim H

In the present study, we compared the expression patterns of neuritin mRNA in the dentate gyrus of hippocampal formation following single (1xECS) or repeated elctroconvulsive seizures (8xECS) treatments to the...
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