- Sex- and Age-Related Changes in Connexin 43 Expression in Normal Rat Bladder
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Song SH, Joo HT, Cho HW, Hwang HW, Lee KH, Kim DK
- KMID: 2232788
- Int Neurourol J.
- 2011 Mar;15(1):25-28.
PURPOSE: Gap junctions are intercellular channels to facilitate electrical and metabolic communication between adjacent cells. Connexin 43 is the most predominant type of connexin expressed on rat detrusor muscle cells.... -
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- A study on the expression of connexin 43 in the experimental tooth movement of rat
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Lim JH, Kang KH, Lee JJ, Kim EC, Kim SC
- KMID: 1923797
- Korean J Orthod.
- 2001 Oct;31(5):525-534.
Bone remodeling in response to force requires coordinated actions of osteoblasts, osteoclasts, osteocytes, and periodontal ligament cells. Coordination among these cells may be mediated, in part, by cell-to-cell communication via... -
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- Spinal Gap Junction Channels in Neuropathic Pain
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Jeon YH, Youn DH
- KMID: 2151665
- Korean J Pain.
- 2015 Oct;28(4):231-235.
- doi: 10.3344/kjp.2015.28.4.231
Damage to peripheral nerves or the spinal cord is often accompanied by neuropathic pain, which is a complex, chronic pain state. Increasing evidence indicates that alterations in the expression and... -
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- Partial Outlet Obstruction Induced Alterations of Rat Urinary Bladder Muscle
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Han HS, Kim IK, Kim DY
- KMID: 2092836
- Korean J Anat.
- 2004 Oct;37(5):403-410.
Partial outlet obstruction induced by benign prostatic hypertrophy or urethral stricture are common urologic conditions showing voiding dysfunction. This study was performed to compare the effects of short-term partial outlet... -
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- Development of the Three-Dimensional Perfusion Culture Technology for the Salivary Ductal Cells
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Kim JW, Kim JM, Choi JS
- KMID: 2448987
- Int J Thyroidol.
- 2018 Nov;11(2):160-166.
- doi: 10.11106/ijt.2018.11.2.160
BACKGROUND AND OBJECTIVES: Salivary hypofunction is one of the common side effects after radioiodine therapy, and its pathophysiology is salivary ductal stenosis resulting from ductal cell injury. This study aimed... -
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- Neuroprotective potential of imatinib in global ischemia-reperfusion-induced cerebral injury: possible role of Janus-activated kinase 2/signal transducer and activator of transcription 3 and connexin 43
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Wang J, Bai T, Wang N, Li H, Guo X
- KMID: 2466565
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):11-18.
- doi: 10.4196/kjpp.2020.24.1.11
The present study was aimed to explore the neuroprotective role of imatinib in global ischemia-reperfusion-induced cerebral injury along with possible mechanisms. Global ischemia was induced in mice by bilateral carotid... -
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- Effects of Mirodenafil, a Phosphodiesterase-5 Inhibitor, on Female Rat Bladder in a Partial Bladder Outlet Obstruction Model: Physiological and Immunohistochemical Aspects
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Kang JY, Kim EK, Kim KM
- KMID: 2061517
- Korean J Urol.
- 2013 May;54(5):339-344.
- doi: 10.4111/kju.2013.54.5.339
PURPOSE: We investigated the effects of mirodenafil, a phosphodiesterase-5 inhibitor developed in South Korea, on the female rat bladder in a partial bladder outlet obstruction (BOO) model. MATERIALS AND METHODS: Thirty-six... -
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- The Efficacy of Connexin 43 Expression in the Myocardium as an Early Ischemic Marker in Forensic Autopsy
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Ahn JW, Huh GY
- KMID: 1785232
- Korean J Leg Med.
- 2015 Feb;39(1):6-11.
- doi: 10.7580/kjlm.2015.39.1.6
The postmortem diagnosis of ischemic heart disease is sometimes difficult for forensic pathologists especially when microscopic ischemic change in the myocardium is not detected at the early stages of ischemic... -
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- Expression of Connexin 43 in the Myocardium in Sudden Unexplained Nocturnal Death Syndrome
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Huh GY, Ahn JW, Kim EY
- KMID: 2165004
- Korean J Leg Med.
- 2016 May;40(2):33-38.
- doi: 10.7580/kjlm.2016.40.2.33
Sudden unexplained nocturnal death syndrome (SUNDS) occurs predominantly in Southeast Asian people including Koreans. SUNDS is problematic for forensic pathologists because the diagnosis depends on the "exclusion of diagnosis." Moreover,... -
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- Effects of Connexin Expression on Detrusor Overactivity in Male Patients with Bladder Outlet Obstruction Caused by Benign Prostatic Hyperplasia
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Cha SH, Kim JC, Hwang TK
- KMID: 2293526
- Korean J Urol.
- 2004 Sep;45(9):897-902.
PURPOSE: Detrusor overactivity is frequently associated with bladder outlet obstruction, which may be related with increased electrical coupling. The effects of connexin 43(Cx43) and connexin 26(Cx26) mRNA expressions on the... -
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- Expression Pattern of Gap Junction Protein, Connexin 26 and 43 in Human Middle Ear Cholesteatomas
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Choung YH, Park K, Kang SO, Shin YR, Cho MJ, Yoon YR
- KMID: 2276545
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Jan;49(1):29-34.
BACKGROUND AND OBJECTIVES: A human cholesteatoma in the middle ear is characterized by the presence of a keratinizing epithelium from hyperproliferative properties. It needs intercellular signal exchange through gap junctions... -
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- Sex Differences in Hippocampal Neuronal Sensitization by Nicotine in M. gerbils
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Hur YN, Lee J, Sohn SC, Won CG, Lee HH, Kim DH, Choi SH, Shin KH, Chun BG
- KMID: 1500234
- Korean J Physiol Pharmacol.
- 2013 Oct;17(5):405-409.
- doi: 10.4196/kjpp.2013.17.5.405
We studied the sex different nicotine effect on evoked population spike amplitudes (ePSA) and connexin (Cx) expression in the hippocampus CA1 area of gerbils. Acute doses of nicotine bitartrate (0.5... -
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- The Gradient Model of the Rabbit Sinoatrial Node
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Dobrzynski H, Lei M, Jones SA, Lancaster , Boyett MR
- KMID: 2071577
- Korean J Physiol Pharmacol.
- 2002 Aug;6(4):173-182.
The sinoatrial (SA) node is a complex and inhomogeneous tissue in terms of cell morphology and electrical activity. There are two models of the cellular organisation of the sinoatrial node:... -
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- Type 2 Diabetes Induces Prolonged P-wave Duration without Left Atrial Enlargement
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Li B, Pan Y, Li X
- KMID: 2363690
- J Korean Med Sci.
- 2016 Apr;31(4):525-534.
- doi: 10.3346/jkms.2016.31.4.525
Prolonged P-wave duration has been observed in diabetes. However, the underlying mechanisms remain unclear. The aim of this study was to elucidate the possible mechanisms. A rat model of type... -
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- Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment
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Lee H, Kim KC, Hong YM
- KMID: 2447196
- Korean J Pediatr.
- 2019 Mar;62(3):95-101.
- doi: 10.3345/kjp.2018.06856
PURPOSE: Increased apoptosis was recently found in the hypertrophied left ventricle of spontaneously hypertensive rats (SHRs). Although the available evidence suggests that apoptosis can be induced in cardiac cells by... -
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- A Study of the Bystander Effect and Its Enhancement in HSV-TK Gene Therapy Using a Murine Neuroblastoma Model
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Cho HS, Kim MK, Park CY
- KMID: 2335600
- J Korean Pediatr Soc.
- 2002 Mar;45(3):354-361.
PURPOSE: Selective introduction of genes conferring chemosensitivity into proliferating tumor cells may be used to treat cancer. We first investigated the bystander effect of retrovirus-mediated gene transfer of herpes simplex... -
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- Upregulation of Connexin43 Expression in Mitral Valves in a Rabbit Model of Hypercholesterolemia
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Kwon JB, Park CB, Sa YJ, Kim YD, Moon SW, Kim CK
- KMID: 2289071
- Korean J Thorac Cardiovasc Surg.
- 2010 Aug;43(4):356-363.
BACKGROUND: Connexin 43-mediated gap junctional communication plays an important role in atherosclerosis. Numerous studies have demonstrated a correlation between mitral valve annular calcification and atherosclerotic disease. However, the relevance of... -
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- Effect of retinoic acid on the bystander effect in gene therapy using the Herpes Simplex Virus thymidine kinase
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Park JY, Kim CH, Jung TH, Albelda SM
- KMID: 2318020
- Tuberc Respir Dis.
- 1997 Feb;44(1):162-174.
BACKGROUND: Metabolic cooperation via gap junctional intercellular communication (GJIC) is an important mechanism of the bystander effect in gene therapy using the Herpes Simplex Virus thymidine kinase/ganciclovir (HSVtk) 'prodrug' system.... -
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- Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43
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Shen F, Huang WL, Xing BP, Fang X, Feng M, Jiang CM
- KMID: 2425502
- Psychiatry Investig.
- 2018 Oct;15(10):919-925.
- doi: 10.30773/pi.2018.06.29
OBJECTIVE: Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR-221/222. This study is to explore whether genistein could improve depression by altering... -
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- Minimal Requirement of Limbal Epithelium for Successful Limbal Cell Transplantation in Rabbit Corneas
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Yang YR, Choi NY, Kim JH, Kim MS
- KMID: 2337329
- J Korean Ophthalmol Soc.
- 2006 Apr;47(4):613-620.
PURPOSE: To investigate the minimal requirements of the limbal epithelium for successful limbal stem cell transplantation and the healing process. METHODS: Nine rabbits were divided into 4, 6, and 8 clock-hour... -
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