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A Case of Cholesteatoma Extended Both into the Cochlea and IAC

Choi HG, Song JJ, Park MW, Chang SO

Labyrinthine fistula caused by cholesteatoma can make various complications according to the site of the lesion. The lateral canal, superior canal ampulla, posterior canal and promontory of the cochlea are...
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The observation of the effect of ototoxic diuretics and hypoxia on guinea pig's cochlea with click-evoked otoacoustic emission

Jung HW, Chang SO

  • KMID: 1684699
  • Korean J Otolaryngol-Head Neck Surg.
  • 1993 Oct;36(5):884-889.
No abstract available.
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Cochlear Implantation Via a Scala Vestibuli in Postmeningitic Ossified Cochlea

Kim BY, Jung SW, Kang MK, Kang MJ

  • KMID: 2276875
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Apr;51(4):390-393.
Obstruction of the fluid spaces of the cochlea was previously thought to contraindicate cochlear implantation due to difficulties of electrodes insertion and questions about potential benefits. However, the concept of...
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Microanatomical Study of the Extradural Middle Fossa Approach for Preventing Cochlear Damage

Jung SM, Jang SJ, Ahn TH

  • KMID: 2339807
  • J Korean Neurosurg Soc.
  • 2004 Nov;36(5):353-357.
OBJECTIVE: The objective is to describe the relationship of anatomical landmark required for the middle fossa approach to preservation of hearing. METHODS: Dissection of 16 fixed human cadaveric heads was...
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Development of Vestibular Organ and Cochlea

Hwang CH

Inner ear is an important organ that is responsible for balance and hearing. It is composed of two complicated major subunits, vestibular organ and cochlea. During development, both functional units...
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Effect of nicotine on the structure of cochlea of guinea pigs

Abdel-Hafez AMM, Elgayar SA, Husain OA, Thabet HS

Smoking has been positively associated with hearing loss in human. However, its effect on the cochlea has not been previously evaluated. Aim of work is to investigate the effect of...
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The Role of "Supporting Cells" in the Cochlea

Zhao LD, Li XQ, Schacht J

  • KMID: 1611632
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Dec;45(12):1120-1124.
No abstract available.
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Role of Nicotinic Acetylcholine Receptor on Efferent Inhibition in Cochlear Hair Cell

Im GJ

The alpha9alpha10 nicotinic acetylcholine receptors (nAChRs) mediates efferent inhibition of hair cell function within the auditory sensory organ. Gating of the nAChRs leads to activation of calcium-dependent potassium channels to...
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Noise Induced Changes of Glucocorticoid Receptors in Rat Cocohlea

You JS, Lim HH, Choi JO

  • KMID: 2274304
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Feb;40(2):277-285.
It has been suggested that glucocorticoid receptors are present in inner ear tissues and may act in stress related mechanism of cochlea. The purpose of this study was to determine...
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Expression of deafness protein Tmie in postnatal developmental stages of C57BL/6J mice

Karuppasamy S, Nam Y, Jung H, Suh JG

Loss-of function mutations in the transmembrane inner ear expressed (Tmie/TMIE) gene have been shown to cause deafness in mice and humans (DFNB6). Previous studies report that the circling mouse can...
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Over-expression of myosin7A in cochlear hair cells of circling mice

Kim YY, Nam H, Jung H, Kim B, Suh JG

Circling mouse (C57BL/6J-cir/cir) deleted the transmembrane inner ear (Tmie) gene is an animal model for human non-syndromic recessive deafness, DFNB6. In circling mouse, hair cells in the cochlea have degenerated...
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A Case of Profuse Cerebrospinal Fluid Otorrhea with Common Cavity Cochlea in Adult

Lee YH, Kim KY, Shin SH

  • KMID: 2012386
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Mar;51(3):269-272.
Cerebrospinal fluid (CSF) otorrhea with inner ear anomaly and common cavity anomaly in adults is very rare, especially as a first symptom except hearing loss. Surgical intervention is the primary...
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Effects of Ginkgo biloba extract on the cochlear damage induced by local gentamicin installation in guinea pigs

Jung HW, Chang SO, Kim CS, Rhee CS, Lim DH

Investigations evaluating the protective effect of Ginkgo biloba extract (EGb) on gentamicin (GM) ototoxicity were undertaken. Guinea pigs treated with 5 mg/kg gentamicin sulfate on the round window niche...
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Two Cases of Electrode Kinking in Cochlear Implantation

Lim S, Kim H, Kim JH, Im GJ

Less traumatic electrode insertion along the basal turn of cochlea is essential to cochlear implantation. However, immoderate attempts to insert the electrode beyond the point of resistance can result in...
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Localization of Phosphoinositide Specific Phospholipase Cbeta Isozymes in Rat Cochlea

Park C, Han SH, Suh HK, Jung HH, Hwang SJ, Jung K, Lim HH

  • KMID: 2074345
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Feb;42(2):145-151.
BACKGROUND AND OBJECTIVES: Phosphoinositide specific phospholipase C (PLC) plays a pivotal role in the transmembrane signal transduction pathways by catalyzing the hydrolysis of phosphoinositide 4,5-bisphosphate (PIP2) to yield the intracellular...
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Mechanism of Efferent Inhibition in Cochlear Hair Cell

Im GJ

Efferent neurons release acetylcholine to inhibit sensory hair cells of the inner ear. The alpha9alpha10 nicotinic acetylcholine receptor (nAChR) mediates efferent inhibition of hair cell function within the auditory sensory...
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Cochlear Fistula: Report of 2 Cases

Jung HW, Rhee CS, Lee JH, Kwon TY

  • KMID: 1550861
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Sep;40(9):1344-1347.
Labyrinthine fistula is not infrequent findings in cholesteatoma surgery. Fistula most commonly involve the horizontal semicircular canal, but a fistula into the cochlea is rare. The authors describe two cases...
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The Past and Present of the Research on Cochlear Stem Cell

Lee DH

Hearing loss is the most frequent sensory deficit in the human population and can occur at any age. Hearing loss ranges from mild to profound, can be conductive, sensorineural or...
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Auditory Effects of Microperfused Lidocaine on Guinea Pig Cochlea

Woo HY, Cho KR, Choi JH, Chung SW, Han DH, Cho CK

  • KMID: 2276077
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jan;47(1):9-14.
OBJECTIVES: Lidocaine is one of the therapeutic trials to treat tinnitus. However, the exact mechanism of the effect of lidocaine remains unclear. The aim of this study was to elucidate...
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Two Cases of Intracochlear Schwannoma

Park MW, Jang JH, Park MH

Intracochlear schwannoma is a rare tumor arising from Schwann cells limited to the cochlea. Most of the cases have been found incidentally at autopsies or during surgeries. Today, gadoliniumenhanced magnetic...
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