- Elevated Serum Levels of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine and Their Relationships with Eosinophilic Inflammatory Markers in Children with Allergic Diseases
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- KMID: 2299451
- Korean J Asthma Allergy Clin Immunol.
- 2012 Dec;32(4):216-223.
BACKGROUND: Thymus and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) are known as important mediators in allergic inflammation. Recently many researchers have focused on these mediators, but the role of... -
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- Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes
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Yano C, Saeki H, Komine M, Kagami S, Tsunemi Y, Ohtsuki M, Nakagawa H
- KMID: 2264803
- Ann Dermatol.
- 2015 Apr;27(2):152-156.
- doi: 10.5021/ad.2015.27.2.152
BACKGROUND: CC chemokine ligand 17 (CCL17) and CCL22 are the functional ligands for CCR4. We previously reported that inhibitors of nuclear factor-kappa B and p38 mitogen-activated protein kinase (p38 MAPK),... -
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- Anti-Inflammatory Effect of Quercetagetin, an Active Component of Immature Citrus unshiu, in HaCaT Human Keratinocytes
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Kang GJ, Han SC, Ock JW, Kang HK, Yoo ES
- KMID: 1502516
- Biomol Ther.
- 2013 Mar;21(2):138-145.
Citrus fruit contain various flavonoids that have multiple biological activities. However, the content of these flavonoids are changed during maturation and immature Citrus is known to contain larger amounts than... -
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- The Relationship between Atopic Dermatitis, Thymus and Activation-Regulated Chemokine/CCL17, Quality of Life, and Attention Deficit-Hyperactivity Disorder in Preschool Children
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Park DH, Chung SH, Shim JW, Kim DS, Jung HL, Park MS, Shim JY
- KMID: 2315131
- Pediatr Allergy Respir Dis.
- 2011 Sep;21(3):215-225.
PURPOSE: Atopic dermatitis may impair quality of life and lead to attention deficit-hyperactivity disorder (ADHD). Thymus and activation-regulated chemokine (TARC)/CCL17 may serve as a new biomarker for atopic dermatitis. We... -
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- Anti-inflammatory Activity of Fucoidan with Blocking NF-kappaB and STAT1 in Human Keratinocytes Cells
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Ryu MJ, Chung HS
- KMID: 2312897
- Nat Prod Sci.
- 2015 Sep;21(3):205-209.
- doi: 10.0000/nps.2015.21.3.205
Fucoidan, a sulfated polysaccharide is found in several types of edible brown algae. It has shown numerous biological activities; however, the molecular mechanisms on the activity against atopic dermatitis have... -
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- Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients
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Lew W, Nakamura K, Tada Y, Kwahck H, Chang SK, Tamaki K
- KMID: 1974521
- Immune Netw.
- 2002 Dec;2(4):223-226.
- doi: 10.4110/in.2002.2.4.223
BACKGROUND: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the... -
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- Increased Serum Thymus and Activation-regulated Chemokine (TARC) Levels in Children with Atopic Dermatitis
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Song TW, Kwon BC, Choi SY, Shin YH, Lee KE, Yang HS, Kim KW, Kim ES, Sohn MH, Kim KE
- KMID: 2314384
- Pediatr Allergy Respir Dis.
- 2005 Sep;15(3):250-256.
PURPOSE: Thymus and activation-regulated chemokine (TARC) is responsible for the trafficking of Th2 lymphocytes into sites of allergic inflammation. We tested whether TARC is a useful marker for childhood atopic... -
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- Correlation between Different Chemokines Induced by Specific Allergens in Atopic Dermatitis
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Chang YS, Jeoung EY, Kim CR, Yum MK, Lee HB, Oh JW
- KMID: 2314574
- Pediatr Allergy Respir Dis.
- 2007 Dec;17(4):404-411.
PURPOSE:Many patients with atopic dermatitis have shown different responses to treatment or different prognosis dependenting on the kinds of offending allergens. We attempted to evaluate the difference of mechanism in... -
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- Expression of TARC in Nasal Epithelial Cells by IL-4/IL-13 and TNF-alpha in Allergic Rhinitis
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Lee KH, Kim SW, Shin SY, Cho JS
- KMID: 2131937
- J Rhinol.
- 2008 Nov;15(2):129-133.
BACKGROUND: Thymus and Activation-Regulated Chemokine (TARC) is a highly specific ligand for CCR4 expressed in Th2 lymphocytes. Local production of TARC may play an important role in the induction and... -
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- Increased Expression and Role of Thymic Stromal Lymphopoietin in Nasal Polyposis
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Kimura S, Pawankar R, Mori S, Nonaka M, Masuno S, Yagi T, Okubo K
- KMID: 1803324
- Allergy Asthma Immunol Res.
- 2011 Jul;3(3):186-193.
- doi: 10.4168/aair.2011.3.3.186
PURPOSE: Nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, Th2 type lymphocytes, fibroblasts, goblet cells... -
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- Transforming growth factor-beta promoted vascular endothelial growth factor release by human lung fibroblasts
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Park SU, Shin JH, Shim JW, Kim DS, Jung HL, Park MS, Shim JY
- KMID: 2127996
- Korean J Pediatr.
- 2008 Aug;51(8):879-885.
- doi: 10.3345/kjp.2008.51.8.879
PURPOSE: The human lung fibroblast may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, which are important in airway remodeling. Vascular endothelial growth factor (VEGF) induces mucosal... -
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- Investigation of Immune-Regulatory Effects of Mageumsan Hot Spring via Protein Microarray In Vitro
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Hahn HJ, Kim JS, Kim YH, Lee YB, Yu DS, Kim JW
- KMID: 2419174
- Ann Dermatol.
- 2018 Jun;30(3):322-330.
- doi: 10.5021/ad.2018.30.3.322
BACKGROUND: Empirical evidences for efficacy of hot spring (HS) water in inflammatory skin disorders have not been substantiated with sufficient, immunological “hard evidenceâ€. Mageumsan HS water, characterized by its weakly-alkaline... -
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- Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid
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Joo YA, Chung H, Yoon S, Park JI, Lee JE, Myung CH, Hwang JS
- KMID: 2351678
- Biomol Ther.
- 2016 Sep;24(5):529-535.
- doi: 10.4062/biomolther.2016.011
Atopic dermatitis (AD) results from gene and environment interactions that lead to a range of immunological abnormalities and breakdown of the skin barrier. Protease-activated receptor 2 (PAR2) belongs to a... -
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- Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy
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Nakata J, Hirota T, Umemura H, Nakagawa T, Kando N, Futamura M, Nakamura Y, Ito K
- KMID: 2444118
- Asia Pac Allergy.
- 2019 Apr;9(2):e18.
- doi: 10.5415/apallergy.2019.9.e18
BACKGROUND: Atopic dermatitis (AD) in infants is often related to food allergies (FA). The beneficial effects of lactic acid bacteria towards allergic diseases have been reported, but there are few... -
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- Selective Inhibition of β-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis
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Matsuda-Hirose H, Yamate T, Goto M, Katoh A, Kouji H, Yamamoto Y, Sakai T, Uemura N, Kobayashi , Hatano Y
- KMID: 2461985
- Ann Dermatol.
- 2019 Dec;31(6):631-639.
- doi: 10.5021/ad.2019.31.6.631
BACKGROUND: The canonical Wnt/β-catenin signaling pathway is a fundamental regulatory system involved in various biological events. ICG-001 selectively blocks the interaction of β-catenin with its transcriptional co-activator cyclic AMP response... -
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