- Current state-of-the-art in human cell transformation in culture
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Rhim JS
- KMID: 1729586
- Yonsei Med J.
- 1991 Sep;32(3):195-206.
- doi: 10.3349/ymj.1991.32.3.195
The immortalization and transformation of cultured human cells has far-reaching implications for both cell and cancer biology. Human cell transformation studies will increase our understanding of the mechanisms underlying carcinogenesis... -
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- Malignant Transformation of Nodular Hyperplasia in the Thyroid: A Case Report
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In HS, Kim DW, Yoon HK
- KMID: 1945349
- J Korean Radiol Soc.
- 2007 Dec;57(6):507-509.
- doi: 10.3348/jkrs.2007.57.6.507
Thyroid carcinogenesis is traditionally thought to originate 'de novo'. However, it is debatable whether a malignant transformation can possibly arise from a benign thyroid nodule, as suggested for the malignant... -
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- Transformation of CD5-Negative Follicular Lymphoma into CD5-Positive Diffuse Large B-Cell Lymphoma: A Case Report
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Kim HK, Cho IS, Lee HK, Choi YH, Cho SM, Moon HJ, Lee JA
- KMID: 2263487
- Korean J Med.
- 2012 Aug;83(2):263-267.
Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of aggressive lymphomas. Approximately 10% of DLBCL cases express CD5 as a surface antigen. CD5-positive DLBCL can occur as the... -
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- Clinical Factors Predicting for Neoplastic Transformation of Gastric Hyperplastic Polyps
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Kang HM, Oh TH, Seo JY, Joen TJ, Seo DD, Shin WC, Choi WC, Kim JY
- KMID: 1718426
- Korean J Gastroenterol.
- 2011 Oct;58(4):184-189.
- doi: 10.4166/kjg.2011.58.4.184
BACKGROUND/AIMS: Hyperplastic polyps (HPs) are the most common cause of all benign epithelial gastric polyps, constituting 30 to 93%. Although gastric HPs are usually considered as benign lesions compared with... -
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- A Case of Concurrent Non-Intestinal Type Adenocarcinoma and Inverted Papilloma in a Maxillary Sinus
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Kim YW, Shin JW, Lee KH, Park SW
- KMID: 2457194
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2019 Aug;62(8):465-469.
- doi: 10.3342/kjorl-hns.2018.00486
Inverted papilloma is a benign epithelial tumor that arises from the sinonasal epithelium and occurs in 0.5–4% of all sinonasal tumors. Although benign, it is associated with malignant transformation in... -
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- Expression of CD44 in Preinvasive Disease and Invasive Cancer in Cervix
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Park JH, Joo JG, Lee KW, Shin BS, Kim KH, Yoon MS
- KMID: 2143477
- Korean J Gynecol Oncol Colposc.
- 2002 Mar;13(1):20-27.
OBJECTIVE: this study was carried out to evaluate the clinicopathologic signigicance of standard & variant isoform CD44-v5, v6 in cervical intraepithelial neoplasia(CIN) and squamous cell carcinoma. METHODS: by means of... -
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- Hairy cell transformation of human peripheral blood lymphocytes by Coxiella burnetii
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Lee WY
- KMID: 1107401
- Yonsei Med J.
- 1993 Mar;34(1):11-21.
- doi: 10.3349/ymj.1993.34.1.11
Hairy cell (HC) transformation of human peripheral blood lymphocytes (PBL) by Coxiella burnetii was studied to clarify the significance of persistency of C. burnetii in a hairy cell line (designated... -
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- Molecular Targeting of ERKs/RSK2 Signaling Axis in Cancer Prevention
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Yoo SM, Cho SJ, Cho YY
- KMID: 2380866
- J Cancer Prev.
- 2015 Sep;20(3):165-171.
- doi: 10.15430/JCP.2015.20.3.165
RSK2 is a downstream signaling protein of ERK1 and ERK2 and plays a key role in physiological homeostasis. For this reason, RSK2 is a highly conserved protein among the p90RSK... -
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- Malignant Transformation of Intrathoracic Ancient Neurilemmoma in a Patient without Von Recklinghausen's Disease
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Chu YC, Yoon YH, Han HS, Han JY, Kim JM, Park IS
- KMID: 2157640
- J Korean Med Sci.
- 2003 Apr;18(2):295-298.
- doi: 10.3346/jkms.2003.18.2.295
Malignant transformation of a neurilemmoma is an exceedingly rare event. We describe a case of intrathoracic ancient neurilemmoma undergoing a malignant change in a 39-yr-old man. The patient presented with... -
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- Multiple myeloma and chronic myelogenous leukemia: a case report with literature review
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Klenn PJ, Hyun BH, Lee YH, Zheng WY
- KMID: 1092423
- Yonsei Med J.
- 1993 Sep;34(3):293-300.
- doi: 10.3349/ymj.1993.34.3.293
This is the case of a 71 year old male who developed multiple myeloma (MM) and chronic myelogenous leukemia (CML) within a two year period. The patient initially presented with... -
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- Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence
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Jalali E, Ferneini E, Rengasamy , Tadinada A
- KMID: 2389895
- Imaging Sci Dent.
- 2017 Jun;47(2):135-140.
- doi: 10.5624/isd.2017.47.2.135
Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents... -
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- Clinicopathologic characteristics of ovarian clear cell carcinoma in the background of endometrioma: a surveillance strategy for an early detection of malignant transformation in patients with asymptomatic endometrioma
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Son JH, Yoon S, Kim S, Kong TW, Paek J, Chang SJ, Ryu HS
- KMID: 2430927
- Obstet Gynecol Sci.
- 2019 Jan;62(1):27-34.
- doi: 10.5468/ogs.2019.62.1.27
OBJECTIVE: This study aimed to analyze the clinical features of clear cell carcinoma in relation to endometriosis and to determine an appropriate surveillance strategy for the early detection of malignant... -
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- Autophagy and cancer
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Choi KS
- KMID: 1120129
- Exp Mol Med.
- 2012 Feb;44(2):109-120.
- doi: 10.3858/emm.2012.44.2.033
Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic integrity by degrading aged or malfunctioning organelles and damaged or misfolded proteins. However, autophagy also plays a complicated... -
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- Alternative Splicing and Its Impact as a Cancer Diagnostic Marker
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Kim YJ, Kim HS
- KMID: 2166488
- Genomics Inform.
- 2012 Jun;10(2):74-80.
- doi: 10.5808/GI.2012.10.2.74
Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. It allows a limited number of genes to encode various proteins... -
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- CT Images of a Malignant-Transformed Ovarian Mature Cystic Teratoma with Rupture: a Case Report
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Wang PC, Yang TL, Pan HB
- KMID: 1385405
- Korean J Radiol.
- 2008 Oct;9(5):458-461.
- doi: 10.3348/kjr.2008.9.5.458
A malignant transformation or a tumor rupture is a rare complication of ovarian mature cystic teratoma (MCT). A tumor rupture in a malignant-transformed MCT has never been reported in the... -
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- Carcinogenesis of Murine Astrocytes in Culture
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Choi GW, Kim MC, Chung H, Lee SP, Yeo HT, Cho SH
- KMID: 2188359
- J Korean Neurosurg Soc.
- 1999 Mar;28(3):300-309.
Astrocytes play important roles in normal brain development and the physiological processes. In particular, 30% of the brain volume consists of astrocytes, and they are the primary target cell in... -
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- Ectopic Over-expression of Oncogene Pim-2 Induce Malignant Transformation of Nontumorous Human Liver Cell Line L02
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Ren K, Duan W, Shi Y, Li B, Liu Z, Gong J
- KMID: 1792950
- J Korean Med Sci.
- 2010 Jul;25(7):1017-1023.
- doi: 10.3346/jkms.2010.25.7.1017
In order to prove that ectopic over-expression of Pim-2 could induce malignant transformation of human liver cell line L02, three groups of cells were set up including human liver cell... -
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- Reactive Oxygen Species and Cancer
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Choi I
- KMID: 2168243
- Hanyang Med Rev.
- 2013 May;33(2):118-122.
- doi: 10.7599/hmr.2013.33.2.118
Reactive Oxygen Species (ROS) are a class of signaling molecules that regulate intracellular signaling cascades in response to external stimuli. Once accumulated in cells, they can damage DNA modifying gene... -
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- Oncogene expressions detected by in situ hybridization of squamous metaplasia, dysplasia and primary lung cancer in human
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Lee JD, Lee DH, Park SS, Shin DH, Chung HC, Lee JH
- KMID: 1421458
- J Korean Med Sci.
- 1989 Sep;4(3):121-127.
- doi: 10.3346/jkms.1989.4.3.121
In order to elucidate the dynamic changes of oncogene expression in the sequential cascade of squamous metaplasia, dysplasia, and squamous cell carcinoma of the bronchial epithelium, hybridization in situ was... -
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- CT and MRI Findings of Sclerosing Angiomatoid Nodular Transformation of the Spleen: Spoke Wheel Pattern
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Karaosmanoglu DA, Karcaaltincaba M, Akata D
- KMID: 1100105
- Korean J Radiol.
- 2008 Jul;9(Suppl):S52-S55.
- doi: 10.3348/kjr.2008.9.s.s52
Sclerosing angiomatoid nodular transformation of the spleen is a recently described benign pathologic entity that is characterized by round shaped vascular spaces that are lined by endothelial cells, and the... -
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