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NF-kappaB Activation in T Helper 17 Cell Differentiation

Park SH, Cho G, Park SG

CD28/T cell receptor ligation activates the NF-kappaB signaling cascade during CD4 T cell activation. NF-kappaB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently,...
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Studies on the B Cell Proliferation and Differentiation Factors in Human B Cell System

Lee KJ, Chung YH, Lee JH

  • KMID: 2208482
  • J Korean Pediatr Soc.
  • 1994 Oct;37(10):1386-1396.
We have studied the function of lymphokines on human tonsillar B cell prolifertion and differentiation. B cells were stimulated with Staphylococcus aureus Cowanl (SAC) or anti- bead. The followings showed the...
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Effects of Ascorbic Acid on Osteoblast Differentiation in MC3T3-E1 Cells

Yang HM, Seo HS

  • KMID: 2317709
  • Soonchunhyang Med Sci.
  • 2013 Dec;19(2):93-98.
OBJECTIVE: Vitamin C is an essential agent for cell differentiation for cell. However, for osteogenic differentiation a combined medium of vitamin C, phosphoglyceride and dexamethasone is used. Individual effect of...
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Studies on the Determining Factors at Each Stage of Germinal Center B Cell Differentiation

Choe JS, Choi YS

  • KMID: 1550787
  • Korean J Immunol.
  • 1999 Jun;21(2):159-164.
To delineate the individual role of follicular dendritic cells (FDC) and T cells at each stage of GC B cell differentiation at the clonal level and to analyze the signals...
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Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation

Cho HR, Hong SB, Kim YI, Lee JW, Kim NI

The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we...
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Identification of genes concordantly expressed with Atoh1 during inner ear development

Yoon H, Lee DJ, Kim MH, Bok J

The inner ear is composed of a cochlear duct and five vestibular organs in which mechanosensory hair cells play critical roles in receiving and relaying sound and balance signals to...
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Transcriptional repression of type I procollagen genes during adipocyte differentiation

Yi TG, Choi HM, Park RW, Sohn KY, Kim IS

  • KMID: 1457541
  • Exp Mol Med.
  • 2001 Dec;33(4):269-275.
Adipocyte differentiation is a very complex process in which whole-cell changes are accompanied. Among them, type I procollagen gene has been shown to specifically decrease during adipocyte differentiation; however, little...
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Granular Cell Tumor of the Thyroid

Kang HJ, Hong EK, Park MH, Lee JD

  • KMID: 1725346
  • Korean J Pathol.
  • 1998 Jan;32(1):63-67.
Granular cell tumor is not uncommon and is a well recognized entity which may arise at virtually any site of the body. However, occurrence in the thyroid is extremely rare...
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The biological effects of fibronectin typeIII 7-10 to MC3T3-E1 osteoblast

Hong JU, Choi SM, Han SB, Chung CP, Rhyu IC, Lee YM, Ku Y

No abstract available.
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Comparative Analysis of Squamous Cell Differentiation by Histologic Subtypes in Basal Cell Carcinoma

Oh ST, Chong SJ, Park CJ, Park YM, Cho SH, Lee JY, Kim JW, Kim SY, Cho BK

  • KMID: 2087043
  • Korean J Dermatol.
  • 2005 Nov;43(11):1475-1481.
BACKGROUND: There has been no general agreement on classifying basal cell carcinoma (BCC), and little is known about the squamous cell differentiations of each subtype of BCC. BCC is a...
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Nuclear receptor regulation of stemness and stem cell differentiation

Jeong Y, Mangelsdorf DJ

Stem cells include a diverse number of toti-, pluri-, and multi-potent cells that play important roles in cellular genesis and differentiation, tissue development, and organogenesis. Genetic regulation involving various transcription...
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Calcium overload is essential for the acceleration of staurosporine-induced cell death following neuronal differentiation in PC12 cells

Seo SR, Seo JT

Differentiation of neuronal cells has been shown to accelerate stress-induced cell death, but the underlying mechanisms are not completely understood. Here, we find that early and sustained increase in cytosolic...
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Effect of suramin on differentiation of human stomach cancer cell lines

Choe G, Kim WH, Park JG, Kim YI

This study was designed to demonstrate that differentiation of stomach cancer cells can be modified by microenvironmental change and to look for a method inducing or promoting tumor cell...
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The Relationship between Expression of E-Cadherin, Clinical Staging and Differentiation in Squamous Cell Carcinomas of the Head and Neck

Koo YA, Na KS, Park MG, Han KS, Park YM, Sim JW

  • KMID: 2074401
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Sep;43(9):967-971.
BACKGROUND AND OBJECTIVES: In recent years, much attention has been directed towards cell adhesion molecules. This study was designed to confirm the significance of E-cadhcrin as a marker for differentiation...
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T Cell Differentiation and Th17

Mo JH

  • KMID: 2276908
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Aug;51(8):688-693.
No abstract available.
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Genetic controls of Th17 cell differentiation and plasticity

Dong C

CD4+ T lymphocytes play a major role in regulation of adaptive immunity. Upon activation, naive T cells differentiate into different functional subsets. In addition to the classical Th1 and Th2...
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The Current Status of Directed Differentiation Technology

Lee SE, Choi D

The direct reprogramming of a terminally differentiated cell into another lineage using defined combinations of factors has fundamentally changed traditional concepts of the inalterability of differentiated cells. Many studies have...
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Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells

Zhao Y, Sun Q, Wang S, Huo B

BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies...
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Effect of Resveratrol on Cell Differentiation and Mineralization in Cultured Odontoblasts

Shin SH, Kim JS, Kim SG, Go DS, Yu SK, Kim CS, Park JC, Kim DK

Resveratrol (3,4′,5,-trihydroxystilbene), a phytoalexin present in grapes, exerts a variety of actions to reduce superoxides, prevents diabetes mellitus, and inhibits inflammation. Resveratrol acts as a chemo-preventive agent and induces apoptotic...
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MicroRNA-27 Promotes Odontoblast Differentiation via Wnt1 Signaling

Cho JH, Kim SG, Park BS, Go DS, Park JC, Kim DK

MicroRNA (miRNA, miR) is essential in regulating cell differentiation either by inhibiting mRNA translation or by inducing its degradation. However, the role of miRNA in odontoblastic cell differentiation is still...
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