- The Expression of Caspase 3 and p21 in Renal Cell Carcinoma
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Yeo JK, Yoon DK, Yoon CY, Kim CH
- KMID: 2292269
- Korean J Urol.
- 2002 Jan;43(1):1-6.
PURPOSE: The objective of this study was to evaluate the Caspase 3 and p21 expression level and to understand the correlation between Caspase 3 expression and the clinical factors in... -
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- Control of Mitochondrial Dynamics by Fas-induced Caspase-8 Activation in Hippocampal Neurons
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Cho HM, Sun W
- KMID: 2165558
- Exp Neurobiol.
- 2015 Sep;24(3):219-225.
- doi: 10.5607/en.2015.24.3.219
Cells undergo apoptosis mainly via two pathways-the mitochondrial pathway and the cytosolic pathway. It has been well documented that activation of the mitochondrial pathway promotes mitochondrial fragmentation and inhibition of... -
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- Effects of Magnesium sulfate on the expression of caspase-3 and caspase-9 of cytotrophoblasts under hypoxic condition
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Lee GS, Kim SJ, Hur M, Park SH, Lee HJ, Lee WS, Shin JC
- KMID: 2076856
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):647-650.
OBJECTIVE: To determine the effect of magnesium sulfate (MgSO4) on the expression of caspase-3 and caspase-9 of cytotrophoblasts in vitro under normal and hypoxic condition as assessed immunoblot analyses. METHODS: Normal... -
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- Induction of Apoptosis by Vibrio vulnificus Cytolysin Through Activation of Caspase-3 in Endothelial Cells
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Park BH, Kwon KB, Lee YH, Jang JH, Park JW
- KMID: 1571535
- J Bacteriol Virol.
- 2001 Dec;31(4):333-341.
No abstract available. -
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- Preliminary Study of Expression of Caspase mRNA and Apoptosis in Squamous Cell Carcinoma and Basal Cell Carcinoma
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Lee GY, Kim MH, Choi HY, Myung KB
- KMID: 2250258
- Korean J Dermatol.
- 2003 Jan;41(1):7-14.
BACKGROUND: Although many recent reports have suggested an important role of caspase in apoptosis and tumor, little is known about the role of caspase in cutaneous carcinoma. OBJECT: The purpose... -
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- The Study of Expression of Caspase-3 in Bladder Cancer and Renal Cell Carcinima
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Lee SW, Myung SC, Kim YS
- KMID: 2290424
- Korean J Urol.
- 1999 Dec;40(12):1610-1614.
PURPOSE: The caspase (ICE/CED-3) family of proteases have been implicated to play a important role in apoptosis and caspase-3(CPP32, YAMA, Apopain) exhibits the highest similarity to CED-3 which produced by... -
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- A Study of Apoptosis in Pemphigus Vulgaris
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Roh BH, Whang KU, Cho MK, Park YL, Lee JS, Lee CW
- KMID: 2087378
- Korean J Dermatol.
- 2007 Jul;45(7):650-658.
BACKGROUND: Pemphigus vulgaris is an autoimmune bullous dermatoses of skin and mucosa characterized by loss of adhesion between keratinocytes, a process known as acantholysis. Apoptosis, programmed cell death, may participate... -
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- Activation of Caspase-3 in Hydrogen Peroxide-Induced Apoptosis of Human Leukemia HL 60 Cells
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Jeon S, Woo CW, Lee J, Sohn J, Lee KC, Son C, Lee J
- KMID: 2278318
- Korean J Pediatr Hematol Oncol.
- 2004 Oct;11(2):228-235.
PURPOSE: Reactive oxygen species have been recognized as a common signaling mediator in diverse stimuli-induced apoptosis and hydrogen peroxide is a natural one of those reactive oxygen species. This study... -
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- Activation of Caspase-3 During Photoreceptor Degeneration in rd Mouse Retina
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Kim DH, Kim JA, Joo CK
- KMID: 2125132
- J Korean Ophthalmol Soc.
- 2001 Feb;42(2):365-372.
Retinal degeneration caused by a hereditary defect in the genome is reported in a few animals and it leads to blindness. rd mouse is one of the well studied animal... -
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- Caspase-3/CPP32 Immunoreactivity and Its Correlation with Frequency of Apoptotic Bodies in Prostate Adenocarcinoma and Benign Prostatic Hyperplasia
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Kang DG, Choi NG
- KMID: 1884993
- Korean J Urol.
- 2001 Jul;42(7):707-712.
PURPOSE: Apoptosis is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase-3, a group of cysteine proteases, ier in cases with intermediate (Gleason score 5-7) and high-grade (Gleason... -
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- Caspase 3 and Ki-67 Immunoreactivity and Its Correlation with Frequency of Apoptosis in Gastric Adenomas and Carcinomas
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Sohn JH, Chae SW, Choi KC, Shin HS
- KMID: 1725815
- Korean J Pathol.
- 2001 Aug;35(4):286-290.
BACKGROUND: Apoptosis, also known as programmed cell death, is under genetic control and is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase 3, a group of cystein... -
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- A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells
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Jang J, Yoon Y, Oh DJ
- KMID: 2416091
- Kidney Res Clin Pract.
- 2017 Sep;36(3):224-231.
- doi: 10.23876/j.krcp.2017.36.3.224
BACKGROUND: Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There... -
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- Correlation between bcl-2 and Caspase-3 Expression and Proliferating Activity in Squamous Neoplasia of the Uterine Cervix
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Park KS, Kang MS, Yoon HK
- KMID: 1725733
- Korean J Pathol.
- 2000 Nov;34(11):919-926.
Detailed mechanism of uterine cervical cancer progression still remains unclear. Altered programmed cell death (apoptosis) and cellular proliferation are associated with the development of neoplasia. The authors investigated the expressions... -
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- Caspase-3 Activation Leads to Apoptosis of Human Gastric Epithelial Cells Infected with Helicobacter pylori
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Kim JM, Kim JS, Jung HC, Song IS, Kim CY
- KMID: 2084935
- Korean J Gastroenterol.
- 1999 Jun;33(6):765-775.
BACKGROUND/AIMS: Infection with Helicobacter pylori activates a proinflammatory gene program in human gastric epithelial cells and is associated with significant epithelial cell damage. We evaluated whether H. pylori infection could... -
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- Effect of Hypoxia on the Signal Transduction of Apoptosis in Osteoblasts
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Park YJ, Oh ST, Kang KH, Kim SC
- KMID: 1976475
- Korean J Orthod.
- 2003 Dec;33(6):453-463.
Mammalian cell is critically dependent on a continuous supply of oxygen. Even brief periods of oxygen deprivation can result in profound cellular damage. The aim of this study was to... -
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- Tacrolimus (FK506) Induced Apoptotic Signal Transduction Pathway
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Jung MR, Choi SJ, Chung SY
- KMID: 2117082
- J Korean Surg Soc.
- 2007 Nov;73(5):359-365.
PURPOSE: This study examined the effects of Tacrolimus (FK506) on the expression of the apoptotic signal transduction proteins of Jurkat human T-lymphocytes. METHODS: The cell viability was examined by a... -
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- Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells
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Kang JI, Hong JY, Choi JS, Lee SK
- KMID: 2164225
- Biomol Ther.
- 2016 May;24(3):320-327.
- doi: 10.4062/biomolther.2015.145
Columbianadin (CBN), a natural coumarin from Angelica decursiva (Umbelliferae), is known to have various biological activities including anti-inflammatory and anti-cancer effects. In this study, the anti-proliferative mechanism of actions mediated... -
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- Cell Death Induction Mechanism of Non-small Cell Lung Cancer Cell Line, NCI-H1703 by Docetaxel
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Ha HC, Kim YD, Song SH, Park CS, Kim JW
- KMID: 1878599
- Korean J Thorac Cardiovasc Surg.
- 2006 Sep;39(9):668-673.
BACKGROUND: Docetaxel has been effectively used as an anti-cancer chemotherapuetic agent for various tumor treatments including lung cancer. However, the cell death induction mechanism(s) involved with docetaxel treatment in lung... -
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- Adriamycin Induced Apoptosis of H9c2 Cardiomyocytes via a Caspase-Independent Pathway
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Jeon MH, Youn HJ, Lee JH, Lee JH
- KMID: 1938857
- Korean Circ J.
- 2004 Jan;34(1):76-83.
- doi: 10.4070/kcj.2004.34.1.76
BACKGROUND: The cardiotoxicity of adriamycin limits its clinical usefulness as a powerful drug for solid tumors and malignant hematological disease. Although the exact mechanism by which it causes cardiac damage... -
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- MiR-484 Protects Rat Myocardial Cells from Ischemia-Reperfusion Injury by Inhibiting Caspase-3 and Caspase-9 during Apoptosis
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Liu H, Li S, Jiang W, Li Y
- KMID: 2470910
- Korean Circ J.
- 2020 Mar;50(3):250-263.
- doi: 10.4070/kcj.2019.0107
BACKGROUND AND OBJECTIVES: To reveal the detail mechanism of miR-484 on myocardial ischemia-reperfusion (MI/R) injury. METHODS: Rats model of MI/R injury was established based on control (Con; sham operate) group, ischemia-reperfusion... -
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