- mechanism of Cell Death induced by ZnCl2 and Calmodulin Antagonist in Human Retinoblastoma Cells
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Joung HJ, Eum YH, Park HT, Yun IH
- KMID: 2124592
- J Korean Ophthalmol Soc.
- 2000 Dec;41(12):2686-2698.
No Abstract Available. -
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- Role of Calmodulin in the Generation of Reactive Oxygen Species and Apoptosis Induced by Tamoxifen in HepG2 Human Hepatoma Cells
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Lee YS
- KMID: 2071579
- Korean J Physiol Pharmacol.
- 2002 Aug;6(4):187-192.
Tamoxifen, an antiestrogen, has previously been shown to induce apoptosis in HepG2 human hepatoblastoma cells through activation of the pathways independent of estrogen receptors, i.e., intracellular Ca2+ increase and generation... -
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- Regulation of GTP-binding state in RalA through Ca2+ and calmodulin
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Park JB
- KMID: 755118
- Exp Mol Med.
- 2001 Mar;33(1):54-58.
RalA GTPase, a member of Ras superfamily proteins, shows alternative forms between the active GTP-binding and the inactive GDP-binding states. Ral-specific guanine nucleotide exchange factor such as RalGDS interacts with... -
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- Differential Inhibition of MPP+- or 6-Hydroxydopamine-induced Cell Viability Loss in PC12 Cells by Trifluoperazine and W-7
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Lee CS
- KMID: 1600082
- Korean J Physiol Pharmacol.
- 2005 Aug;9(4):247-253.
The present study assessed the effect of calmodulin antagonists trifluoperazine and W-7 against the cytotoxicity of MPP+ and 6-hydroxydopamine (6-OHDA) in relation to the mitochondrial dysfunction and cell death in... -
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- A Memory Molecule, Ca2+/Calmodulin-Dependent Protein Kinase II and Redox Stress; Key Factors for Arrhythmias in a Diseased Heart
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Song YH
- KMID: 2224956
- Korean Circ J.
- 2013 Mar;43(3):145-151.
- doi: 10.4070/kcj.2013.43.3.145
Arrhythmias can develop in various cardiac diseases, such as ischemic heart disease, cardiomyopathy and congenital heart disease. It can also contribute to the aggravation of heart failure and sudden cardiac... -
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- Depression of Ca2+ influx in complement C5a-stimulated neutrophils by calmodulin inhibitors
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Ham DS, Kim HH, Han ES, Lee CS
- KMID: 2071531
- Korean J Physiol Pharmacol.
- 1998 Feb;2(1):109-117.
Role of Ca2+/calmodulin complex in intracellular Ca2+ mobilization in neutrophils has not been clearly elucidated. In this study, effects of chlorpromazine, trifluoperazine and imipramine on the intracellular Ca2+ mobilization, including Ca2+ influx, in... -
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- Bex1 Participates in Muscle Regeneration by Regulating Myogenic Satellite Cell Differentiation
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Koo JH
- KMID: 2312060
- Lab Anim Res.
- 2010 Jun;26(2):145-151.
Bex1 protein is upregulated in regenerating muscle and interacts with calmodulin, a Ca2+-binding protein involved in cell cycle regulation. Following cardiotoxin-induced injury the regenerating muscle of Bex1 knock-out mice exhibits... -
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- Three Unrecorded Species Belonging to Penicillium Section Sclerotiora from Marine Environments in Korea
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Park MS, Chung D, Baek K, Lim YW
- KMID: 2455696
- Mycobiology.
- 2019 Jun;47(2):165-172.
- doi: 10.1080/12298093.2019.1601330
Species that belong to Penicillium section Sclerotiora are commonly found in various terrestrial environments, but only a few have been reported in marine environments. Because the number of Penicillium species... -
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- Protective effects of kaempferol against cardiac sinus node dysfunction via CaMKII deoxidization
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An M, Kim M
- KMID: 2133262
- Anat Cell Biol.
- 2015 Dec;48(4):235-243.
- doi: 10.5115/acb.2015.48.4.235
Kaempferol exerts cardioprotective actions through incompletely understood mechanisms. This study investigated the molecular mechanisms underlying the cardioprotective effects of kaempferol in sinus node dysfunction (SND) heart. Here, we demonstrate that... -
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- Attenuation of Hemoglobin-Induced Constriction in the Rabbit Basilar Artery by Protein Kinase C Inhibitor and Ca2+/Calmodulin-Dependent Protein Kinase Inhibitor
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Kim BN, Kang SD, Kim JM
- KMID: 2067533
- J Korean Neurosurg Soc.
- 1998 Jun;27(6):700-714.
According to the widely accepted concept that contraction of arterial smooth muscle is dependent on the Ca2+/calmodulin and protein kinase C(PKC) systems, it has been recently proposed that activation of... -
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- New Records of Four Species Belonging to Eurotiales from Soil and Freshwater in Korea
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Pangging M, Nguyen TT, Lee HB
- KMID: 2455695
- Mycobiology.
- 2019 Jun;47(2):154-164.
- doi: 10.1080/12298093.2018.1554777
Four strains of Penicillium and Talaromyces species are described and illustrated in an inventory of fungal species belonging to Eurotiales. The strains, CNUFC-DDS17-1, CNUFC-DDS27-1, CNUFC-PTM72-1, and CNUFC-YJW3-31, were isolated from... -
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- The Effects of Cyclosporin A on the Signal Transduction System in the Rat Brain
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Koo YJ, Kang UG, Roh MS, Ahn YM, Park JB, Kim YS
- KMID: 1985333
- Korean J Psychopharmacol.
- 2001 Dec;12(4):294-300.
The most important molecular mechanisms of intraneuronal signal transduction are those mediated by calcium and reversible protein phosphorylation. Although many studies pursued the activation of the protein kinases in the... -
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- Role of Protein Kinase in Spontaneous Phasic Contraction of Cat Gastric Smooth Muscle
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Sim SS, Choi JC, Kim MS, Kim CJ, Jo YH
- KMID: 2240381
- Korean J Gastroenterol.
- 2000 Mar;35(3):283-290.
Gastric muscle contraction is known to be regulated by complicated mechanism. In the present study, the role of protein kinase in the modulation of spontaneous gastric phasic contraction was investigated. METHODS: Circular muscle... -
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- Effects of Trifluoperazine on the PC12 Cell Injury
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Kim W, Choi Y, Lee HY, Kim Y, Lee KY
- KMID: 2275050
- Chonnam Med J.
- 1997 Jun;33(1):89-104.
Trifluoperazine(TFP) is a well known antipsycotic phenothiazine derivative. TFP is also known as a calmodulin antagonist in molecular level. Although there have been many reports on the role of TFP... -
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- First Report of Two Colletotrichum Species Associated with Bitter Rot on Apple Fruit in Korea – C. fructicola and C. siamense
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Park MS, Kim BR, Park IH, Hahm SS
- KMID: 2428814
- Mycobiology.
- 2018 Jun;46(2):154-158.
- doi: 10.1080/12298093.2018.1478220
Bitter rot caused by the fungal genus Colletotrichum is a well-known, common disease of apple and causes significant yield loss. In 2013, six fungal strains were isolated from Fuji apple... -
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- The role of calmodulin in regulating calcium-permeable PKD2L1 channel activity
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Park EY, Baik JY, Kwak M, So I
- KMID: 2443609
- Korean J Physiol Pharmacol.
- 2019 May;23(3):219-227.
- doi: 10.4196/kjpp.2019.23.3.219
Polycystic kidney disease 2-like-1 (PKD2L1), polycystin-L or transient receptor potential polycystin 3 (TRPP3) is a TRP superfamily member. It is a calcium-permeable non-selective cation channel that regulates intracellular calcium concentration... -
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- Diversity of Marine-Derived Aspergillus from Tidal Mudflats and Sea Sand in Korea
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Lee S, Park MS, Lim YW
- KMID: 2366448
- Mycobiology.
- 2016 Dec;44(4):237-247.
- doi: 10.5941/MYCO.2016.44.4.237
Aspergillus (Trichocomaceae, Eurotiales, and Ascomycota) is a genus of well-defined asexual spore-forming fungi that produce valuable compounds such as secondary metabolites and enzymes; however, some species are also responsible for... -
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- Endothelial Dysfunction-Its Molecular Mechanism and Potential Implication in Therapy
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Kim CH
- KMID: 1895023
- Korean Circ J.
- 2006 Sep;36(9):609-611.
- doi: 10.4070/kcj.2006.36.9.609
Endothelial dysfunction is known to be early stage of atherosclerosis and its presence leads to poor prognosis. Recently many basic researchs were done to elucidate the basic mechanism related to... -
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- Calcium/Calmodulin Kinase II Activity of Hippocampus in Kainate-Induced Epilepsy
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Lee MC, Ban SS, Woo YJ, Kim SU
- KMID: 2157576
- J Korean Med Sci.
- 2001 Oct;16(5):643-648.
- doi: 10.3346/jkms.2001.16.5.643
This study investigated calcium/calmodulin kinase II (CaMKII) activity related to long-standing neuronal injury of the hippocampus in kainate (KA)-induced experimental temporal lobe epilepsy. Epileptic seizure was induced by injection of... -
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- The Affinity of Calmodulin-Affigel for Inositol Triphosphate Kinase From Bovine Brain
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Lim SW, Kim JH
- KMID: 2377305
- Yeungnam Univ J Med.
- 1990 Jun;7(1):39-50.
- doi: 10.12701/yujm.1990.7.1.39
The one event on signaling mechanism is the cleavage by adenyl cyclase of ATP into second messenger, cyclic AMP. The other transfer system of inositol metabolism, it is widely recognized... -
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