- Erratum to "Melatonin-Induced PGC-1α Improves Angiogenic Potential of Mesenchymal Stem Cells in Hindlimb Ischemia" [Biomol. Ther. 28 (2020) 240-249]
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Lee JH, Han YS, Lee SH
- KMID: 2517204
- Biomol Ther.
- 2021 Jul;29(4):454-454.
- doi: 10.4062/biomolther.2021.454
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- Erratum to "Cripto Enhances Proliferation and Survival of Mesenchymal Stem Cells by Up-Regulating JAK2/STAT3 Pathway in a GRP78-Dependent Manner" [Biomol. Ther. 26 (2018) 464-473]
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Yun S, Yun CW, Lee JH, Kim S, Lee SH
- KMID: 2517171
- Biomol Ther.
- 2021 Jul;29(4):452-453.
- doi: 10.4062/biomolther.2021.452
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- Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
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Natesan V, Kim SJ
- KMID: 2517154
- Biomol Ther.
- 2021 Jul;29(4):365-372.
- doi: 10.4062/biomolther.2020.204
Type 2 diabetes mellitus (T2DM) leads to many health problems like diabetic nephropathy (DN). One of the key factors for chronic kidney disease and end-stage renal disease (ESRD) is T2DM.... -
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- Salicylamide Enhances Melanin Synthesis in B16F1 Melanoma Cells
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Ito Y, Sato K
- KMID: 2517170
- Biomol Ther.
- 2021 Jul;29(4):445-451.
- doi: 10.4062/biomolther.2020.222
Salicylamide, a non-steroidal anti-inflammatory drug (NSAID), is used as an analgesic and antipyretic agent. We have previously shown that several NSAIDs have anti-melanogenic properties in B16F1 melanoma cells. In contrast,... -
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- Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches
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Thein W, Po WW, Choi WS, Sohn UD
- KMID: 2517153
- Biomol Ther.
- 2021 Jul;29(4):353-364.
- doi: 10.4062/biomolther.2021.086
The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the... -
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- 4-CMTB Ameliorates Ovalbumin-Induced Allergic Asthma through FFA2 Activation in Mice
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Lee JH, Im DS
- KMID: 2517161
- Biomol Ther.
- 2021 Jul;29(4):427-433.
- doi: 10.4062/biomolther.2020.176
Free fatty acid receptor 2 (FFA2, also known as GPR43), a G-protein-coupled receptor, has been known to recognize short-chain fatty acids and regulate inflammatory responses. FFA2 gene deficiency exacerbated disease... -
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- Bioactive Sphingolipids as Major Regulators of Coronary Artery Disease
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Song JH, Kim GT, Park KH, Park WJ, Park TS
- KMID: 2517155
- Biomol Ther.
- 2021 Jul;29(4):373-383.
Atherosclerosis is the deposition of plaque in the main arteries. It is an inflammatory condition involving the accumulation of macrophages and various lipids (low-density lipoprotein [LDL] cholesterol, ceramide, S1P). Moreover,... -
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- Effects of the Combination of Evogliptin and Leucine on Insulin Resistance and Hepatic Steatosis in High-Fat Diet-Fed Mice
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Shin CY, Lee HY, Kim GH, Park SY, Choi WS, Sohn UD
- KMID: 2517160
- Biomol Ther.
- 2021 Jul;29(4):419-426.
- doi: 10.4062/biomolther.2021.003
In this study, we aimed to investigate the effects of 8 weeks of treatment with a combination of evogliptin and leucine, a branchedchain amino acid, in mice with high-fat diet... -
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- Differential Sensitivity of Wild-Type and BRAF-Mutated Cells to Combined BRAF and Autophagy Inhibition
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Yeom H, Hwang SH, Han BI, Lee M
- KMID: 2517162
- Biomol Ther.
- 2021 Jul;29(4):434-444.
- doi: 10.4062/biomolther.2020.203
BRAF inhibitors are insufficient monotherapies for BRAF-mutated cancer; therefore, we investigated which inhibitory pathway would yield the most effective therapeutic approach when targeted in combination with BRAF inhibition. The oncogenic... -
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- Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives
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Choi HR, Lim H, Lee JH, Park H, Kim HP
- KMID: 2517159
- Biomol Ther.
- 2021 Jul;29(4):410-418.
- doi: 10.4062/biomolther.2020.192
Helicobacter pylori causes chronic gastritis through cag pathogenicity island (cagPAI), vacuolating cytotoxin A (VacA), lipopolysaccharides (LPS), and flagellin as pathogen-related molecular patterns (PAMPs), which, in combination with the pattern recognition... -
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- Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors
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Paudel S, Kim E, Zhu A, Acharya S, Min X, Cheon SH, Kim KM
- KMID: 2517157
- Biomol Ther.
- 2021 Jul;29(4):392-398.
- doi: 10.4062/biomolther.2020.233
In this study, we determined the effect of 24 different synthetic 4-benzylpiperidine carboxamides on the reuptake of serotonin, norepinephrine, and dopamine (DA), and characterized their structure–activity relationship. The compounds with... -
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- Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22
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Hur KH, Ma SX, Lee BR, Ko YH, Seo JY, Ryu HW, Kim HJ, Yoon S, Lee YS, Lee SY, Jang CG
- KMID: 2517156
- Biomol Ther.
- 2021 Jul;29(4):384-391.
- doi: 10.4062/biomolther.2020.212
Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected... -
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- Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene
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Hoang NMH, Kim S, Nguyen HD, Kim M, Kim J, Kim BC, Park D, Lee S, Yu BP, Chung HY, Kim MS
- KMID: 2517158
- Biomol Ther.
- 2021 Jul;29(4):399-409.
- doi: 10.4062/biomolther.2020.208
1,2-Diacetylbenzene (DAB) is a metabolite of 1,2-diethylbenzene, which is commonly used in the manufacture of plastics and gasoline. We examined the neurotoxic effects of DAB in young and old rats,... -
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