- Dopamine-2 and serotonin-2 receptor bindings in antipsychotic medicines from natural products
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Chung IW, Kim SR, Kim EG
- KMID: 2197828
- J Korean Neuropsychiatr Assoc.
- 1992 Sep;31(5):856-868.
No abstract available. -
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- Natural Product-Derived Drugs for the Treatment of Inflammatory Bowel Diseases
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Joo YE
- KMID: 2284894
- Intest Res.
- 2014 Apr;12(2):103-109.
- doi: 10.5217/ir.2014.12.2.103
Natural products have been used as drugs for millennia, and the therapeutic potential of natural products has been studied for more than a century. Since the mid-1880s, approximately 60% of... -
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- Critical Points on the Use of Biologicals in Allergic Diseases and Asthma
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Agache I, Cojanu C, Laculiceanu A, Rogozea L
- KMID: 2462570
- Allergy Asthma Immunol Res.
- 2020 Jan;12(1):24-41.
- doi: 10.4168/aair.2020.12.1.24
Improved understanding of the contribution of immune-inflammatory mechanisms in allergic diseases and asthma has encouraged development of biologicals and small molecules specifically targeting the innate and adaptive immune response. There... -
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- Korean Traditional Medicines as Novel Drugs for Neuropsychiatric Disorders
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Min SK, Hong CH
- KMID: 2286727
- Korean J Psychopharmacol.
- 2007 Jan;18(1):5-17.
This paper reviews history of new drug development in Korea as well as researchs on development of new psychotherapeutic drug from traditional medicines or natural products in Korea. Korea has... -
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- Natural Products for Chemoprevention of Breast Cancer
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Ko EY, Moon A
- KMID: 2380874
- J Cancer Prev.
- 2015 Dec;20(4):223-231.
- doi: 10.15430/JCP.2015.20.4.223
Breast cancer is the primary cause of cancer death in women. Although current therapies have shown some promise against breast cancer, there is still no effective cure for the majority... -
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- Regulation of Neural Stem Cell Fate by Natural Products
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Kim HJ
- KMID: 2432062
- Biomol Ther.
- 2019 Jan;27(1):15-24.
- doi: 10.4062/biomolther.2018.184
Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent... -
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- Biologic Treatment of Severe Asthma
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Kim MH
- KMID: 2435181
- Korean J Med.
- 2018 Apr;93(2):172-180.
- doi: 10.3904/kjm.2018.93.2.172
Beyond the existing scope of asthma treatment, a number of biologics have recently been developed based on the immunopathological mechanism of severe asthma. Severe asthma has a wide variety of... -
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- Sleep-Aids Derived from Natural Products
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Hu Z, Oh S, Ha TW, Hong JT, Oh KW
- KMID: 2420384
- Biomol Ther.
- 2018 Jul;26(4):343-349.
- doi: 10.4062/biomolther.2018.099
Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction. Alternatively, natural... -
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- Medicinal Herbs Effective Against Atherosclerosis: Classification According to Mechanism of Action
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Kim JY, Shim SH
- KMID: 2447852
- Biomol Ther.
- 2019 May;27(3):254-264.
- doi: 10.4062/biomolther.2018.231
Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol,... -
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- Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics
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Bae JH, Yang DH
- KMID: 2409887
- Korean J Gastroenterol.
- 2018 Apr;71(4):192-195.
- doi: 10.4166/kjg.2018.71.4.192
Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, characterized by diffuse mucosal inflammation with bloody diarrhea. The therapeutic goals in UC have evolved from symptomatic relief to... -
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- The use of biologics for severe psoriasis
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Youn SW
- KMID: 2195107
- J Korean Med Assoc.
- 2015 Oct;58(10):917-922.
- doi: 10.5124/jkma.2015.58.10.917
Psoriasis is a life-long chronic relapsing dermatosis that shows waxing and waning of disease despite of a lot of conventional treatment. Severe psoriasis, usually defined by a psoriasis area and... -
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- Development of PCR-ELISA for Detection of HIV-1 in Biomedical Products
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Shim JH, Kim JW, Lee KA, Kwon DH, Myung PK, Kim JO, Lee SH, Park SN, Yoon DY
- KMID: 2239120
- Korean J Lab Med.
- 2004 Feb;24(1):60-66.
BACKGROUND: Biomedical products such as viral vaccines can be contaminated with hazardous viruses during manufacturing processes and storage, thus causing harmful side effects. To assure the safety of biomedical products,... -
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- Antioxidative Activity and Anti-melanogenic Effect of the Extract from the Leaves of Robinia Pseudo-acacia L
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Chung JS, Jin GH, Park YK
- KMID: 2359718
- Ann Dermatol.
- 1999 Jul;11(3):142-146.
- doi: 10.5021/ad.1999.11.3.142
BACKGROUND: Plant extracts have been widely used as important therapeutic drugs for many centuries all over the world. There have been many reports that natural products have various kinds of... -
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- Desensitization for Allergic Reactions to Chemotherapy
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Hong DI
- KMID: 2431627
- Yonsei Med J.
- 2019 Feb;60(2):119-125.
- doi: 10.3349/ymj.2019.60.2.119
Drug desensitization is procedure by which patients can be tolerized to medications that have previously induced hypersensitivity reactions. Initially used in treating hypersensitivity reactions to antibiotics, desensitization is now frequently... -
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- Treatment of Psoriasis
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Youn JI
- KMID: 2184663
- J Korean Med Assoc.
- 2006 Feb;49(2):150-162.
- doi: 10.5124/jkma.2006.49.2.150
Psoriasis is a common, chronic skin disease. The goal of therapy is always to use the appropriate medication to achieve the desired effect while minimizing side effect. The three types... -
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- Biologics for the treatment of pyoderma gangrenosum in ulcerative colitis
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Arivarasan K, Bhardwaj V, Sud S, Sachdeva S, Puri AS
- KMID: 2354955
- Intest Res.
- 2016 Oct;14(4):365-368.
- doi: 10.5217/ir.2016.14.4.365
Pyoderma gangrenosum (PG) is an uncommon extra-intestinal manifestation of inflammatory bowel disease (IBD). Despite limited published literature, biologics have caused a paradigm shift in the management of this difficult-to-treat skin... -
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- A Case of Paradoxical Flare of Pustular Psoriasis after Ustekinumab Therapy
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Kang IH, Shin MK, Lee MH, Jeong KH
- KMID: 2436996
- Korean J Dermatol.
- 2018 Nov;56(9):548-551.
Biologics are the most advanced treatment for psoriasis. Ustekinumab, one of the biologics for psoriasis, is a human monoclonal antibody that binds to the p40 subunit of interleukin-12 and interleukin-23.... -
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- Reversal of Immunogenicity in Pediatric Inflammatory Bowel Disease Patients Receiving Anti-Tumor Necrosis Factor Medications
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Kang E, Khalili A, Splawski J, Sferra TJ, Moses J
- KMID: 2421996
- Pediatr Gastroenterol Hepatol Nutr.
- 2018 Oct;21(4):329-335.
- doi: 10.5223/pghn.2018.21.4.329
Loss of response to anti-tumor necrosis factor (anti-TNF) agents in the treatment of inflammatory bowel disease (IBD) is a major consideration to maintain sustained response. Reversal of immunogenicity can re-establish... -
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- The inhibitory effect of natural bioactives on the growth of pathogenic bacteria
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Kim JS, Kim Y
- KMID: 2313326
- Nutr Res Pract.
- 2007 Dec;1(4):273-278.
The objective of this study was to evaluate the inhibitory activity of natural products, against growth of Escherichia coli (ATCC 25922) and Salmonella typhimurium (KCCM 11862). Chitosan, epigallocatechin gallate (EGCG),... -
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- Development of One-step Real-time Reverse Transcription-polymerase Chain Reaction in Combination with Automated RNA Extraction for Detection and Quantitation of Hepatitis A Virus
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Kim BG, Jeong HS, Baek SY, Shin JH, Kim JO, Min KI, Ryu SR, Min BS, Kim DK, Park MK, Ahn MJ, Lee SH, Park SN
- KMID: 1615502
- J Bacteriol Virol.
- 2003 Sep;33(3):209-218.
One-step real-time reverse transcription-polymerase chain reaction (RT-PCR) assay using the MagNA Pure LC and LightCycler(TM) system was developed and validated for the detection and quantitation of hepatitis A virus (HAV)... -
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