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Irritant Contact Dermatitis Induced by Benzalkonium Chloride (Zephanon®)

Joe HJ, Kim SA, Lee KS

  • KMID: 2162232
  • Korean J Dermatol.
  • 2016 Mar;54(3):224-225.
No abstract available.
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Allergic contact dermatitis to benzalkonium chloride in eyedrops

Huh CH, Han KH, Eun HC

  • KMID: 1563390
  • J Asthma Allergy Clin Immunol.
  • 2000 Feb;20(1):135-139.
No abstract available.
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Allergic Contact Dermatitis due to EDTA and Benzalkonium Chloride in Eyedrops

Eun HC, Chun HS

  • KMID: 2165180
  • Allergy.
  • 1994 Jun;14(2):235-239.
Both EDTA and benzalkonium chloride, commonly used preservatives in ophthalmic preparations, are known to be rare sensitizers. A 61-year-old man presented with edema and erythema of the right eyelid with...
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Acute toxicity of benzalkonium chloride in Balb/c mice following intratracheal instillation and oral administration

Lee H, Park K

Benzalkonium chloride is a cationic surfactant widely used as a disinfectant, preservative, and sanitizer in many public places as well as domestically. The purpose of this study is to compare...
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Experimental Studies on the Sterilization of The Soft Contact Lens

Kim SB

  • KMID: 2107052
  • J Korean Ophthalmol Soc.
  • 1974 Mar;15(1):9-15.
Mycon-soft lenses (made by Tokyo contact lens Co., Japan) were contaminated experimentally with coagulase positive staphylococcus aureus and pseudomonas aeruginosa and sterilizing effects of some disinfectants (3% H2O2, 6% H2O2,...
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A Case of Allergic Contact Dermatitis Due to Benzethonium Chloride

Kang KS, Park CW, Lee CH

  • KMID: 2250231
  • Korean J Dermatol.
  • 2003 Apr;41(4):527-529.
Benzethonium chloride is quaternary ammonium compounds, which may cross-react with benzalkonium chloride. It has been used in the treatment of burns, ulcers, wounds, and infected dermatoses and also present in...
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Effect of Trusopt and Xalatan on the Proliferation of Cultured Subconjunctival Fibro blasts

Kim JW, Kim EC, Lee SS

  • KMID: 2336881
  • J Korean Ophthalmol Soc.
  • 1999 Jun;40(6):1642-1648.
The prior long-term use of topical anti-glaucoma medications has been suggested as an adverse factor for the outcome of trabeculectomy. The mechanism of action is still unclear. This study investigates...
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Effect of Benzalkonium, Mitomycin-C and Dexamethasone on Stress in Trabecular Meshwork Cells

Kim BM, Kim JW

PURPOSE: To investigate the effects of benzalkonium chloride (BAC), mitomycin C (MMC) and dexamethasone (DEX) on cellular stress in cultured human trabecular meshwork cell (HTMC) monolayers. METHODS: HTMCs were cultured in...
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Corrosive Esophagitis with Benzalkonium Chloride in a Two Days Old Neonate

Civan HA, Gulcu D, Erkan T

Benzalkonium chloride (BAC) is a caustic agent which is used in farms, homes and hospitals for cleaning skin and wounds as an antiseptic solution. It may lead to digestive system...
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The Changes in the Corneal Epithelial Barrier by Benzalkonium Chloride and Commonly used Eyedrops

Lee JH, Kim KS

  • KMID: 2205136
  • J Korean Ophthalmol Soc.
  • 1995 Oct;36(10):1655-1661.
To evaluate the corneal epithelial barrier after exposure to Benzalkonium chloride(BAC) or commonly used eyedrops, we measured corneal uptake of 5, 6-carboxyfluorescein(CF) applied to the corneal epithelium of the albino...
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Two Cases of Allergic Contact Dermatitis to Povidone-iodine

Yoo SH, Kim YG, Lee AY

  • KMID: 2230493
  • Korean J Dermatol.
  • 1999 May;37(5):691-693.
Povidone-iodine(PVP-I) is a widely used antiseptic for the skin because of its low toxicity and high germieidal efficacy, Allergic contact dermatitis to PVP-I is known to be rare. Two patients...
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Effect of Nitric Oxide on the Proliferation of Cultured Human Tenon Capsule Fibroblasts Exposed to Benzalkonium Chloride

Kim JW, Kim KH, Cho BJ

  • KMID: 2206656
  • J Korean Ophthalmol Soc.
  • 2003 Aug;44(8):1908-1913.
PURPOSE: To investigate whether the effect of benzalkonium chloride (BAK) on the proliferation of human Tenon capsule fibroblasts (HTCF) is mediated by nitric oxide (NO) in tissue culture . METHODS:...
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Effect of Bimatoprost on the Permeability of Trabecular Meshwork Cell Monolayer

Chang B, Kim JW

PURPOSE: To investigate the effects of bimatoprost on the permeability of cultured human trabecular meshwork cells (HTMC) monolayer. METHODS: HTMCs were cultured until confluency in the inner Transwell chamber and then...
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Toxicity of Benzalkonium Chloride on Corneal Endothelium of Rabbits

Park SK, Hahn YH, Hur B

  • KMID: 2123325
  • J Korean Ophthalmol Soc.
  • 1995 Jul;36(7):1155-1161.
An experimental study was performed on 16 rabbits to evaluate the toxicity of benzalkonium chloride(BAK) on the corneal endothelium. Each rabbit received two drops of 0.01% BAK in the right...
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The Effect of Antiglaucoma Medication on Cultured Human Conjunctival Epithelial Cells

Lee JK, Ryu YH

  • KMID: 2337460
  • J Korean Ophthalmol Soc.
  • 2006 Nov;47(11):1811-1818.
PURPOSE: To investigate the toxicity of a short-term application of timolol maleate, dorzolamide, and benzalkonium chloride (BAC) on human conjunctival epithelial cells in vitro. METHODS: Chang's conjunctival epithelial cell line...
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Periorbital Allergic Contact Dermatitis to Ketotifen Fumarate Eyedrops

Choi WJ, Jue MS, Ro YS

  • KMID: 2301810
  • Korean J Dermatol.
  • 2010 Nov;48(11):989-992.
Ketotifen fumarate (KF) is a widely used drug for prophylaxis and the treatment of allergic conditions. Adverse cutaneous reactions to KF are rare except for dryness of the skin and...
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Effect of Gelrite on the Proliferation of Cultured Human Tenon's Capsule Fibroblasts

Kim JW, Kim KH, Jin YH

  • KMID: 2337092
  • J Korean Ophthalmol Soc.
  • 2003 Feb;44(2):496-501.
PURPOSE: To investigate the effect of Gelrite (Gelrite gellan gum), a natural gelling agent, on the viability and proliferation of human Tenon's capsule fibroblasts in tissue culture. METHODS: We studied...
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Cytotoxicity of Benzalkonium Chloride on the Corneal Epithelial Cell of Rabbit

Lee JS, Jung DY, Oum BS, Kim CD

  • KMID: 2147694
  • J Korean Ophthalmol Soc.
  • 1998 Jul;39(7):1326-1333.
Authors investigated the functional and morphological cytotoxicity of benzalkonium chloride(BAC) used clinically on the cultured corneal epithelial cell of rabbit in vitro. Corneal epithelial cells containing radioactive 51Cr were exposured...
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The Effects of Artificial Tear Formulations and Anti-inflammatory Agents on the Cultured Keratocytes of Rabbit

Lee JS, Oum BS

  • KMID: 2336633
  • J Korean Ophthalmol Soc.
  • 1998 Jan;39(1):42-51.
We investigated the biological effects and cytotoxicity of the artificial tear formulations and anti-inflammatory agents on the cultured keratocytes of rabbit in vitro by using lactate dehydrogenase (LDH) leakage assay...
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The Effect of Benzalkonium Chloride on the Paradoxical Bronchoconstriction with Antiasthmatic Respirator Solution

Lee YJ, Jung JW, Yoon UK, Oh JS, Cha HR

  • KMID: 2051339
  • Pediatr Allergy Respir Dis.
  • 1997 Mar;7(1):47-56.
Recently, some cases of paradoxical bronchoconsthction with the use of nebulized antiasthmatic respirator solutions have been reported. This study was performed to determine whether benzalkonium chloride, contained in several antiasthmatic...
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