- Functional Regulation of Dopamine D₃ Receptor through Interaction with PICK1
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Zheng M, Zhang X, Min C, Choi BG, Oh IJ, Kim KM
- KMID: 2351670
- Biomol Ther.
- 2016 Sep;24(5):475-481.
- doi: 10.4062/biomolther.2016.015
PICK1, a PDZ domain-containing protein, is known to increase the reuptake activities of dopamine transporters by increasing their expressions on the cell surface. Here, we report a direct and functional... -
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- Hyperglycemia Associated with Mirtazapine: A Case Report
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Hong YJ, Park JD, Kim JG
- KMID: 2340533
- J Korean Neuropsychiatr Assoc.
- 2001 Jan;40(1):151-156.
Mirtazapine-a newly developed drug with reduce adverse effects and toxicity of original antidepre-ssants-has been known to have antidepressant effect by enhancing the transmission of norepinephrine and serotonin via blockade of... -
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- A Neurodegenerative Hypothesis of Cytokine-Serotonin Interaction in Major Depression
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Kim YK
- KMID: 2341023
- J Korean Neuropsychiatr Assoc.
- 2004 Jul;43(4):386-392.
A growing body of evidence suggests that major depression is associated with increased productions of pro-inflammatory cytokines such as IL-1, IL-6, IL-12 or TNF-alpha and increased concentrations of prostaglandin E2... -
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- Antiepressant-Associated Mania
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Yoon DJ
- KMID: 2340050
- J Korean Neuropsychiatr Assoc.
- 1997 May;36(3):395-415.
To examine the causative agents, clinical characteristics, management, risk factors, and neurochemical mechanism of the antidepressant-associated mania, MEDLINE searches were conducted. Mania can occur by chance during antideressant treatment or... -
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- Recent Development on Future Antidepressants
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Kim YK
- KMID: 2334640
- J Korean Soc Biol Psychiatry.
- 2004 Jun;11(1):14-25.
The current understanding of the mechanisms of pharmacotherapy for depression is characterized by an emphasis on increasing synaptic availability of serotonin, noradrenaline, and possibly dopamine, while minimizing side effects. The... -
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- A Review of Meta-analysis Studies with Amisulpride
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Bahk WM, Kim W
- KMID: 2286854
- Korean J Psychopharmacol.
- 2004 Sep;15(3):270-275.
Amisulpride, a substituted benzamide derivative, is a newer atypical antipsychotics. It mainly blocks presynaptic dopamine D2/D3 autoreceptors which is preferentially located in prefrontal area and blocks postsynaptic dopamine D2/D3 receptors... -
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- Presynaptic Mechanism Underlying Regulation of Transmitter Release by G Protein Coupled Receptors
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Takahashi , Kajikawa Y, Kimura M, Saitoh N, Tsujimoto
- KMID: 1611227
- Korean J Physiol Pharmacol.
- 2004 Apr;8(2):69-76.
A variety of G protein coupled receptors (GPCRs) are expressed in the presynaptic terminals of central and peripheral synapses and play regulatory roles in transmitter release. The patch-clamp whole-cell recording... -
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- The Function of 5-HT(1A) Receptor and Pharmacotherapy
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Kim W, Bahk WM
- KMID: 2287360
- Korean J Psychopharmacol.
- 2006 May;17(3):253-262.
5-HT(1A) receptor is implicated in the pathogenesis and the therapeutic mechanism of various psychiatric disorders. Especially, the mechanism of action of selective serotonin reuptake inhibitors (SSRIs) was hypothesized that 5-HT(1A)... -
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- Neurobiological Pathophysiology of Attention Deficit Hyperactivity Disorder
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Park HB, Joo Y
- KMID: 2138676
- Yeungnam Univ J Med.
- 2000 Dec;17(2):108-122.
- doi: 10.12701/yujm.2000.17.2.108
BACKGROUND: Models of attention deficit hyperactivity disorder(ADHD) that have proposed a hypodopaminergic state resulting in hypofunction of the prefrontal circuitry have assumed a unitary dopamine system, which largely ignores the... -
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- The effect of typical and atypical antipsychotic drugs on the mRNA expression of rat mesencephalic D2 receptor
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Shon YH, Kim JS
- KMID: 1536883
- J Korean Neurol Assoc.
- 1997 Oct;15(5):1022-1041.
Recently various types of dopamine receptors have been proved to exist in human central nervous system. And the understanding of the of specific function is expected to improve therapeutic effect... -
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- Function of the neuronal M2 muscarinic receptor in asthmatic patients
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Kwon YH, Lee SY, Bak SM, Lee SH, Shin C, Cho JY, Shim JJ, Kang KH, Yoo SH, In KH
- KMID: 2160322
- Tuberc Respir Dis.
- 2000 Oct;49(4):486-494.
- doi: 10.4046/trd.2000.49.4.486
BACKGROUND: The dominant innervation of airway smooth muscle is parasympathetic fibers which are carried in the vagus nerve. Activation of these cholinergic nerves releases acetylcholine which binds to M3 muscarinic... -
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