- Antimalarial Activity of C-10 Substituted Triazolyl Artemisinin
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Park GM, Park H, Oh S, Lee S
- KMID: 2403718
- Korean J Parasitol.
- 2017 Dec;55(6):661-665.
- doi: 10.3347/kjp.2017.55.6.661
We synthesized C-10 substituted triazolyl artemisinins by the Huisgen cycloaddition reaction between dihydroartemisinins (2) and variously substituted 1, 2, 3-triazoles (8a-8h). The antimalarial activities of 32 novel artemisinin derivatives were... -
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- Praziquantel Treatment in Trematode and Cestode Infections: An Update
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Chai JY
- KMID: 2391838
- Infect Chemother.
- 2013 Mar;45(1):32-43.
Status and emerging issues in the use of praziquantel for treatment of human trematode and cestode infections are briefly reviewed. Since praziquantel was first introduced as a broadspectrum anthelmintic in... -
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- The Efficacy of Core Decompression for Treating Avascular Necrosis of the Femoral Head
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Shim KB, Kwon DS, Oh SJ, Kang JS, Moon KH
- KMID: 1465825
- J Korean Hip Soc.
- 2009 Sep;21(3):219-225.
- doi: 10.5371/jkhs.2009.21.3.219
PURPOSE: We evaluated the efficacy of core decompression (CD) for treating early avascular necrosis of the femoral head (ANFH), as well as the effect of an autogeneous bone graft and... -
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- A Case of Mixed Malaria Infection with Severe Hemolytic Anemia after Travel to Angola
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Shin SY, Yu JH, Kim JY, Kim YJ, Woo HY, Kwon MJ, Yeom JS
- KMID: 2170385
- Infect Chemother.
- 2012 Oct;44(5):386-390.
- doi: 10.3947/ic.2012.44.5.386
In Korea, Plasmodium vivax (P. vivax) is the most common agent of malaria infection. However, as travel to regions where malaria is endemic increases, so do the numbers of Plasmodium... -
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- Plasmodium falciparum Genotype Diversity in Artemisinin Derivatives Treatment Failure Patients along the Thai-Myanmar Border
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Congpuong , Hoonchaiyapoom T, Inorn K
- KMID: 2069813
- Korean J Parasitol.
- 2014 Dec;52(6):631-637.
- doi: 10.3347/kjp.2014.52.6.631
Genetic characteristics of Plasmodium falciparum may play a role in the treatment outcome of malaria infection. We have studied the association between diversity at the merozoite surface protein-1 (msp-1), msp-2,... -
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- Early Clinical Results in the Use of a Tantalum Trabecular Metal System For Osteonecrosis of the Femoral Head
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Kim JO, Noh KJ, Park HS, Do NH, Kim TH, Son HS
- KMID: 1465841
- J Korean Hip Soc.
- 2009 Jun;21(2):141-147.
- doi: 10.5371/jkhs.2009.21.2.141
PURPOSE: To evaluate the effectiveness of core decompression using a tantalum trabecular metal system for treatment of early stage osteonecrosis of the femoral head, with a minimum follow-up of 1... -
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- Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats
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Chung MK, Yu WJ, Lee JS, Lee JH
- KMID: 2317813
- Toxicol Res.
- 2013 Mar;29(1):27-34.
This study was conducted to investigate the potential embryo-fetal toxicity and toxicokinetics of the antimalarial agent artesunate (ARTS) in Sprague-Dawley rats. Pregnant rats were administered ARTS daily from gestational day... -
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- Anti-tumor effect of new compound, 127, through the induction of apoptosis
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Baek KH, Han AL, Shin SR, Jin CM, Yu ST, Yoon YW, Kim JD, Choi DY
- KMID: 2281075
- Korean J Pediatr.
- 2009 Jun;52(6):696-700.
- doi: 10.3345/kjp.2009.52.6.696
PURPOSE: We screened more than 350 compounds with an endoperoxide ring structure in search of an anti-leukemic drug and found that compound 127 (c-127) could induce significant cytotoxicity in HL-60... -
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- An Imported Case of Severe Falciparum Malaria with Prolonged Hemolytic Anemia Clinically Mimicking a Coinfection with Babesiosis
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Na YJ, Chai JY, Jung BK, Lee HJ, Song JY, Je JH, Seo JH, Park SH, Choi JS, Kim MJ
- KMID: 2069818
- Korean J Parasitol.
- 2014 Dec;52(6):667-672.
- doi: 10.3347/kjp.2014.52.6.667
While imported falciparum malaria has been increasingly reported in recent years in Korea, clinicians have difficulties in making a clinical diagnosis as well as in having accessibility to effective anti-malarial... -
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- Antimalarial activity of thiophenyl- and benzenesulfonyl-dihydroartemisinin
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Lee SJ, Oh ST, Park GM, Kim TS, Ryu JS, Choi HK
- KMID: 1720504
- Korean J Parasitol.
- 2005 Sep;43(3):123-126.
- doi: 10.3347/kjp.2005.43.3.123
Each diastereomer of 10-thiophenyl- and 10-benzenesulfonyl-dihydroartemisinin was synthesized from artemisinin in three steps, and screened against chloroquine-resistance and chloroquine-sensitive Plasmodium falciparum. Three of the four tested compounds were found to... -
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- Molecular cloning and characterization of peroxiredoxin from Toxoplasma gondii
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Son ES, Song KJ, Shin JC, Nam HW
- KMID: 1039035
- Korean J Parasitol.
- 2001 Jun;39(2):133-141.
- doi: 10.3347/kjp.2001.39.2.133
A cDNA of 1.1 kb comprising the gene encoding the peroxiredoxin of Toxoplasma gondii (TgPrx) has been cloned. The open reading frame of 591 bp was translated into a protein... -
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- Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand
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Krudsood S, Tangpukdee N, Muangnoicharoen S, Thanachartwet V, Luplertlop N, Srivilairit S, Wilairatana P, Kano S, Ringwald P, Looareesuwan S
- KMID: 1720534
- Korean J Parasitol.
- 2007 Jun;45(2):111-114.
- doi: 10.3347/kjp.2007.45.2.111
Chloroquine remains the drug of choice for the treatment of vivax malaria in Thailand. Mixed infections of falciparum and vivax malaria are also common in South-East Asia. Laboratory confirmation of... -
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- Minor liver profile dysfunctions in Plasmodium vivax, P. malaria and P. ovale patients and normalization after treatment
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Tangpukdee N, Thanachartwet V, Krudsood S, Luplertlop N, Pornpininworakij K, Chalermrut K, Phokham S, Kano S, Looareesuwan S, Wilairatana P
- KMID: 1088761
- Korean J Parasitol.
- 2006 Dec;44(4):295-302.
- doi: 10.3347/kjp.2006.44.4.295
Liver function tests were performed in 61 vivax, 54 malariae and 15 ovale malaria patients who were admitted to Bangkok Hospital for Tropical Diseases between 2001 and 2004. The objective... -
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- Drug Resistance and in Vitro Susceptibility of Plasmodium falciparum in Thailand during 1988-2003
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Suwandittakul N, Chaijaroenkul W, Harnyuttanakorn P, Mungthin M, Na Bangchang K
- KMID: 1720623
- Korean J Parasitol.
- 2009 Jun;47(2):139-144.
- doi: 10.3347/kjp.2009.47.2.139
The aim of the present study was to investigate antimalarial drug pressure resulting from the clinical use of different antimalarials in Thailand. The phenotypic diversity of the susceptibility profiles of... -
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- Gametocyte Clearance in Uncomplicated and Severe Plasmodium falciparum Malaria after Artesunate-Mefloquine Treatment in Thailand
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Tangpukdee N, Krudsood S, Srivilairit S, Phophak N, Chonsawat , Yanpanich , Kano S, Wilairatana P
- KMID: 1089464
- Korean J Parasitol.
- 2008 Jun;46(2):65-70.
- doi: 10.3347/kjp.2008.46.2.65
Artemisinin-based combination therapy (ACT) is currently promoted as a strategy for treating both uncomplicated and severe falciparum malaria, targeting asexual blood-stage Plasmodium falciparum parasites. However, the effect of ACT on... -
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